Faculty Opinions recommendation of Pneumatic dilation for persistent dysphagia after antireflux surgery, a multicentre single-blind randomised sham-controlled clinical trial.

Dysphagia following laparoscopic fundoplication for medically refractory gastroesophageal reflux disease (GERD) is common. In patients without an anatomic defect, it has been hypothesized that the ant reflux wrap may be too tight. Therefore, pneumatic dilation may help relieve the obstruction. While retrospective data support this hypothesis, prospective data are lacking. We summarize the @GIJournal discussion held on February 17, 2021, during which the article by Schuitenmaker et al. “Pneumatic dilation for persistent dysphagia after ant reflux surgery, a multicentre single-blind randomized sham-controlled clinical trial” was critically reviewed by our expert Dr. John Pandolfino (JP), and moderated by Dr. Marianna Papademetriou (MP).

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Clinical evaluation of effects of local application of hydrogen peroxide gel (1,7%) as an adjunct to scaling and root planing in patients with chronic periodontitis: a split-mouth single-blind randomized controlled clinical trial

10.26226/morressier.5ac383172afeeb00097a3f1c ◽

2018 ◽

Author(s):

Evelina Vedlugaitė

Keyword(s):

Clinical Trial ◽

Hydrogen Peroxide ◽

Clinical Evaluation ◽

Chronic Periodontitis ◽

Local Application ◽

Controlled Clinical Trial ◽

Scaling And Root Planing ◽

Randomized Controlled Clinical Trial ◽

Randomized Controlled ◽

Single Blind

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Intraoral versus extraoral photobiomodulation therapy in the prevention of oral mucositis in HSCT patients: a randomized, single-blind, controlled clinical trial

Supportive Care in Cancer ◽

10.1007/s00520-021-06228-3 ◽

2021 ◽

Author(s):

Mariana Bitu Ramos-Pinto ◽

Teresa Paula de Lima Gusmão ◽

Jayr Schmidt-Filho ◽

Graziella Chagas Jaguar ◽

Manoela Domingues Martins ◽

...

Keyword(s):

Clinical Trial ◽

Oral Mucositis ◽

Photobiomodulation Therapy ◽

Controlled Clinical Trial ◽

Single Blind

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Intravenous paracetamol versus ketorolac for pain attenuation in patients with renal colic; a randomized, single blind and controlled clinical trial

Journal of Renal Injury Prevention ◽

10.34172/jrip.2020.10 ◽

2020 ◽

Vol 9 (2) ◽

pp. e10-e10

Author(s):

Arash Ardestani Zadeh ◽

Davood Arab ◽

Mohammadreza Moonesan ◽

Majid Mirmohammadkhani ◽

Pouya Morid

Keyword(s):

Clinical Trial ◽

Adverse Effects ◽

Renal Colic ◽

Vital Signs ◽

Analgesic Efficacy ◽

Controlled Clinical Trial ◽

Randomized Controlled ◽

Intravenous Paracetamol ◽

Significant Difference ◽

Single Blind

Introduction: Pain control is an essential care for patients with renal colic in emergency wards. Objectives: This study aimed to compare the analgesic efficacy of intravenous (IV) paracetamol (PC) versus ketorolac (KET) for patients with renal colic. Patients and Methods: In a randomized controlled clinical trial, 110 patients with renal colic referred to the emergency department of Kosar hospital, Semnan between October 2015 and June 2016 were selected. Eighty-eight patients were divided into two groups (44 patients in each group) of PC (1 g/IV) and KET (30 mg/IV). One patient in each group was excluded during the study. Vital signs and pain severity (measured by visual analogue scale [VAS]) of all patients were recorded at admission time 0, 20, 40 and 60 minutes after treatment. Then, the results were compared in two groups. Results: The results showed that at the time of 0, 20, 40 and 60 minutes after the administration of the PC and KET drugs, no significant difference was seen in severity of pain based on VAS score between the two groups (P<0.05). Moreover, there were no significant differences in the vital signs of two groups (P<0.05). No adverse effects were reported in each group. Conclusion: In conclusion, the use of IV-PC and KET in patients with renal colic had similar pain relieving effects without any adverse effects.

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