Faculty Opinions recommendation of Hippocampal-Medial Prefrontal Event Segmentation and Integration Contribute to Episodic Memory Formation.

Author(s):  
Cheryl Grady ◽  
Jenny Rieck
2020 ◽  
Author(s):  
Wei Liu ◽  
Yingjie Shi ◽  
James N Cousins ◽  
Nils Kohn ◽  
Guillen Fernandez

How do we encode our continuous life experiences for later retrieval? Theories of event segmentation and integration suggest that the hippocampus binds separately represented events into an ordered narrative. Using an open-access functional Magnetic Resonance Imaging (fMRI) movie watching-recall dataset, we quantified two types of neural similarities (i.e., activation pattern similarity and within-region voxel-based connectivity pattern similarity) between separate events during movie watching and related them to subsequent retrieval of events as well as retrieval of sequential order. We demonstrate that distinct activation patterns of the hippocampus and medial prefrontal cortex form event memories. By contrast, similar within-region connectivity patterns between events facilitate memory formation and are relevant for the retention of events in the correct sequential order. We applied the same approaches to an independent movie watching fMRI dataset and replicational analyses highlighted again the role of hippocampal activation pattern and connectivity pattern in memory formation. We propose that distinct activation patterns represent neural segmentation of events while similar connectivity patterns encode context information, and therefore integrate events into a narrative. Our results provide novel evidence for the role of hippocampal-medial prefrontal event segmentation and integration in episodic memory formation of real-life experience.


2017 ◽  
Author(s):  
Andrea Greve ◽  
Elisa Cooper ◽  
Roni Tibon ◽  
Richard Henson

Events that conform to our expectations, i.e, are congruent with our world knowledge or schemas, are better remembered than unrelated events. Yet events that conflict with schemas can also be remembered better. We examined this apparent paradox in four experiments, in which schemas were established by training ordinal relationships between randomly-paired objects, while episodic memory was tested for the number of objects on each trial. Better memory was found for both congruent and incongruent trials, relative to unrelated trials, producing memory performance that was a “U-shaped” function of congruency. Furthermore, the incongruency advantage, but not congruency advantage, emerged even if the information probed by the memory test was irrelevant to the schema, while the congruency advantage, but not incongruency advantage, also emerged after initial encoding. Schemas therefore augment episodic memory in multiple ways, depending on the match between novel and existing information.


2021 ◽  
Vol 153 ◽  
pp. 107755
Author(s):  
Benjamin J. Griffiths ◽  
María Carmen Martín-Buro ◽  
Bernhard P. Staresina ◽  
Simon Hanslmayr ◽  
Tobias Staudigl

Author(s):  
Barbara L. Pitts ◽  
Maverick E. Smith ◽  
Kimberly M. Newberry ◽  
Heather R. Bailey

2016 ◽  
Author(s):  
Verena Braun ◽  
Rodika Sokoliuk ◽  
Simon Hanslmayr

AbstractBackgroundTranscranial alternating current stimulation (tACS) is widely used to entrain or modulate brain oscillations in order to investigate causal relationships between oscillations and cognition.ObjectiveIn a series of experiments we here addressed the question of whether event-related, transient tACS in the beta frequency range can be used to entrain beta oscillations in two different domains: episodic memory formation and motor cortex excitability.MethodsIn experiments 1 and 2, 72 healthy human participants engaged in an incidental encoding task of verbal and non-verbal material while receiving tACS to the left and right inferior frontal gyrus (IFG) at 6.8Hz, 10.7Hz, 18.5Hz, 30Hz, 48Hz and sham stimulation for 2s during stimulus presentation.In experiment 3, tACS was administered to M1 at the individual motor beta frequency of eight subjects. We investigated the relationship between the size of TMS induced MEPs and tACS phase.ResultsBeta tACS did not affect memory performance compared to sham stimulation in experiments 1 and 2. Likewise, in experiment 3, MEP size was not modulated by the tACS phase.ConclusionsOur findings suggest that event-related, transient tACS in the beta frequency range cannot be used to modulate the formation of episodic memories or motor cortex excitability. These null-results question the effectiveness of event-related tACS to entrain beta oscillations and modulate cognition.


2013 ◽  
Vol 33 (1) ◽  
pp. 292-304 ◽  
Author(s):  
J. F. Burke ◽  
K. A. Zaghloul ◽  
J. Jacobs ◽  
R. B. Williams ◽  
M. R. Sperling ◽  
...  

2018 ◽  
Vol 41 ◽  
Author(s):  
Dora Kampis ◽  
András Keszei ◽  
Ildikó Király

AbstractWe propose an extension to Mahr & Csibra's (M&C's) theory. For successful episodic memory formation, potentially relevant aspects of a situation need to be identified and encoded online and retained for prospective interactions. To be maximally convincing, the communicator not only has to encode not just any contextual detail, but also has to track information in relation to social partners.


2011 ◽  
Vol 34 (2) ◽  
pp. 407-424 ◽  
Author(s):  
Björn H. Schott ◽  
Torsten Wüstenberg ◽  
Maria Wimber ◽  
Daniela B. Fenker ◽  
Kathrin C. Zierhut ◽  
...  

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