Comparison of Single and Multiple Low-Level Laser Applications After Rapid Palatal Expansion on Bone Regeneration in Rats

Low level laser therapy (LLLT) has been used to relieve pain, inflammation, and wound healing processes. Thus, the skin is overexposed to laser and this effect is not completely understood. This study analyzed the effects of the number of laser applications (three, six, and 10) on the intact skin of the masseteric region in mice of strain HRS/J. The animals(n=30)were equally divided into control (0 J/cm2) and irradiated (20 J/cm2), and each of these groups was further equally divided according to the number of laser applications (three, six, and 10) and underwent LLLT on alternate days. Samples were analyzed by light microscopy and transmission electron microscope (TEM). The animals receiving applications exhibited open channels more dilated between the keratinocytes and photobiomodulation effect on endothelial cells and fibroblasts by TEM. Under the light microscope after 10 laser applications, the type I collagen decreased(P<0.05)compared to the three and six applications. Under these experimental conditions, all numbers of applications provided photobiomodulatory effect on the epidermis and dermis, without damage. More studies are needed to standardize the energy density and number of applications recommended for laser therapy to have a better cost-benefit ratio associated with treatment.

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Effectiveness of blood irradiation by modified intravenous laser (ILIB) on the clinical parameters of fibromyalgia

GSC Advanced Research and Reviews ◽

10.30574/gscarr.2021.7.1.0023 ◽

2021 ◽

Vol 7 (1) ◽

pp. 052-058

Author(s):

Vanessa Helena Pires Diniz ◽

Arthur Diniz Vial ◽

Raquel Tolentino Dornelas Alves

Keyword(s):

Trigger Point ◽

Low Level Laser Therapy ◽

Clinical Parameters ◽

Laser Applications ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Urgent Task ◽

Inflammatory Processes ◽

Irradiate Blood

Pain control remains an urgent task. If the goal is to achieve permanent pain relief and not temporarily mask the pain (masking the pathology), then that goal can only be achieved by treating the pain with physiotherapeutic methods, the most universal and effective of them is low-level laser therapy intensity (LLLT). Treatment methods vary fundamentally in the case of neuropathic pain (nonspecific, primary), which includes pain with trigger point (PT) and nociceptive (specific, secondary) pain, which includes all types of pain resulting from trauma, inflammation, etc. When treating patients with fibromyalgia (FM), which is a chronic condition with high worldwide prevalence, auxiliary therapies have been indicated for the treatment of fibromyalgia including low-level laser. Currently, the low intensity laser has been attached to a bracelet over the radial artery, in order to irradiate blood cells, using a technique called modified ILIB (Intravascular Laser Irradiation of Blood), with improved control of fibromyalgia, of chronic inflammatory processes. This study evaluated the effectiveness of the modified ILIB in improving the clinical parameters of fibromyalgia used to treat a patient who had chronic pain for 20 years, who received conventional treatment associated with two laser applications using the modified ILIB technique.

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Histologic Evaluation of Early Bone Regeneration Treated with Simvastatin Associated with Low-Level Laser Therapy

The International Journal of Oral & Maxillofacial Implants ◽

10.11607/jomi.6990 ◽

2019 ◽

Vol 34 (3) ◽

pp. 658-664

Author(s):

Jamilly de Miranda ◽

Isabela Choi ◽

Maria Moreira ◽

Manoela Martins ◽

Arthur Cortes ◽

...

Keyword(s):

Bone Regeneration ◽

Laser Therapy ◽

Low Level Laser Therapy ◽

Low Level ◽

Low Level Laser ◽

Level Laser ◽

Histologic Evaluation

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Bone regeneration associated with low-level laser therapy in implantology

Journal of Dental Implants ◽

10.4103/jdi.jdi_6_20 ◽

2021 ◽

Vol 11 (1) ◽

pp. 13

Author(s):

KarinaI R Teixeira ◽

JoseA Mendonca ◽

MarcioB Rosa ◽

Rudolf Huebner ◽

MariaE Cortés ◽

...

Keyword(s):

Bone Regeneration ◽

Laser Therapy ◽

Low Level Laser Therapy ◽

Low Level ◽

Low Level Laser ◽

Level Laser

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Effects of Low Level Laser Therapy on Bone Regeneration of Intrabony Defects

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.638.151 ◽

2015 ◽

Vol 638 ◽

pp. 151-154

Author(s):

Gabriela Bereșescu ◽

Monica Monea ◽

Bianca Porca ◽

Alina Cocan ◽

Adriana Maria Monea

Keyword(s):

Bone Formation ◽

Bone Regeneration ◽

Laser Therapy ◽

Histological Study ◽

Test Group ◽

Low Level Laser Therapy ◽

Intrabony Defects ◽

Low Level ◽

Low Level Laser ◽

Level Laser

The aim of this study is to assess the histological efficiency of low level laser therapy (LLLT) with respect to the acceleration of bone regeneration after surgical treatment of intrabony defects. Twenty patients with intrabony defects, aged between 20-45, non-smokers, good health condition present at the time of the surgery, were randomly divided in two groups, control, ten parients, and test group, ten patients. Informed consent was obtained. Each patient presented at least one periodontal defect treated by bone allograft. The test group received postsurgical treatment with low lever laser therapy (LLLT). The equipment used was OsseoPulse AM300, at an intensity of 20mW/cm2, for 20 minutes per day, for 21 consecutive days. The control group received no treatment with LLLT. The bone formation was evaluated in both groups at baseline and 6 months postoperative by the means of tissue biopsy followed by a histological analysis. The histological study of the test samples at 6 months after regeneration showed bone formation without inflammatory cells and occasional nonviable bone consistent with regenerating bone. No evidence of the grafted material was present. The histological study suggests that in 6 months there was new bone formation in the defects treated with LLLT. Clinical data indicate the possibility of more rapid wound closure and subsequent healing in zones treated with LLLT as compared with control.

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