scholarly journals Multimodal nonlinear optical imaging of Caenorhabditis elegans with multiplex coherent anti-Stokes Raman scattering, third-harmonic generation, second-harmonic generation, and two-photon excitation fluorescence

2020 ◽  
Vol 13 (7) ◽  
pp. 072002
Author(s):  
Shinichi Miyazaki ◽  
Philippe Leproux ◽  
Vincent Couderc ◽  
Yu Hayashi ◽  
Hideaki Kano
Keyword(s):  
Raman Scattering ◽  
Harmonic Generation ◽  
Nonlinear Optical ◽  
Second Harmonic ◽  
Third Harmonic Generation ◽  
Third Harmonic ◽  
Two Photon ◽  
Photon Excitation ◽  
Nonlinear Optical Imaging ◽  
Anti Stokes

scholarly journals Nonlinear optical microscopies (NOMs) and plasmon-enhanced NOMs for biology and 2D materials

Nanophotonics ◽  
2020 ◽  
Vol 9 (6) ◽  
pp. 1341-1358
Author(s):  
Jialin Ma ◽  
Mengtao Sun
Keyword(s):  
Raman Scattering ◽  
Nonlinear Optical ◽  
Stimulated Raman Scattering ◽  
Second Harmonic ◽  
2D Materials ◽  
Research Progress ◽  
Two Photon ◽  
Two Dimensional Materials ◽  
Anti Stokes ◽  
Physical Principles

AbstractIn this review, we focus on the summary of nonlinear optical microscopies (NOMs), which are stimulated Raman scattering (SRS), coherent anti-Stokes Raman scattering (CARS), second harmonic generation (SHG), and two-photon excited fluorescence (TPEF). The introduction is divided into two parts: the principle of SRS, CARS, TPEF, and SHG and their application to biology and two-dimensional materials. We also introduce the connections and differences between them. We also discuss the principle of plasmon-enhanced NOM and its application in the above two aspects. This paper not only summarizes the research progress in the frontier but also deepens the readers’ understanding of the physical principles of these NOMs.

scholarly journals Multiphoton Microscopy for Ophthalmic Imaging

2011 ◽  
Vol 2011 ◽  
pp. 1-11 ◽  
Author(s):  
Emily A. Gibson ◽  
Omid Masihzadeh ◽  
Tim C. Lei ◽  
David A. Ammar ◽  
Malik Y. Kahook
Keyword(s):  
Harmonic Generation ◽  
Second Harmonic ◽  
Imaging Techniques ◽  
Multiphoton Microscopy ◽  
Tissue Imaging ◽  
Third Harmonic ◽  
Two Photon ◽  
Disease Mechanisms ◽  
Ophthalmic Imaging ◽  
Anti Stokes

We review multiphoton microscopy (MPM) including two-photon autofluorescence (2PAF), second harmonic generation (SHG), third harmonic generation (THG), fluorescence lifetime (FLIM), and coherent anti-Stokes Raman Scattering (CARS) with relevance to clinical applications in ophthalmology. The different imaging modalities are discussed highlighting the particular strength that each has for functional tissue imaging. MPM is compared with current clinical ophthalmological imaging techniques such as reflectance confocal microscopy, optical coherence tomography, and fluorescence imaging. In addition, we discuss the future prospects for MPM in disease detection and clinical monitoring of disease progression, understanding fundamental disease mechanisms, and real-time monitoring of drug delivery.

scholarly journals Push–pull pyropheophorbides for nonlinear optical imaging

2017 ◽  
Vol 15 (4) ◽  
pp. 947-956 ◽  
Author(s):  
Anjul Khadria ◽  
Yovan de Coene ◽  
Przemyslaw Gawel ◽  
Cécile Roche ◽  
Koen Clays ◽  
...  
Keyword(s):  
Harmonic Generation ◽  
Lipid Membranes ◽  
Nonlinear Optical ◽  
Second Harmonic ◽  
Two Photon ◽  
Donor And Acceptor ◽  
Nonlinear Optical Imaging ◽  
Pyropheophorbide A ◽  
Electron Donor And Acceptor ◽  
Derivatives Of

We have synthesized derivatives of pyropheophorbide-a with electron donor and acceptor groups which localize in lipid membranes and can be used for multi-photon imaging via second harmonic generation and two-photon excited fluorescence.

scholarly journals Optical characterizations of two-dimensional materials using nonlinear optical microscopies of CARS, TPEF, and SHG

Nanophotonics ◽  
2018 ◽  
Vol 7 (5) ◽  
pp. 873-881 ◽  
Author(s):  
Rui Li ◽  
Yajun Zhang ◽  
Xuefeng Xu ◽  
Yi Zhou ◽  
Maodu Chen ◽  
...  
Keyword(s):  
Nonlinear Optical ◽  
Second Harmonic ◽  
2D Materials ◽  
Two Dimensional ◽  
Raman Scattering Spectroscopy ◽  
Two Photon ◽  
Photon Excitation ◽  
Two Dimensional Materials ◽  
Anti Stokes

AbstractIn this paper, we employ the nonlinear optical microscopies of coherent anti-Stokes Raman scattering spectroscopy, two-photon excitation fluorescence, and second harmonic generation to characterize the properties of two-dimensional (2D) materials. With these nonlinear optical microscopy methods, we can not only clearly observe the surface topography of 2D materials but also reveal the quality of 2D materials. These nonlinear optical microscopies offer great potential for characterization of the properties of 2D materials.

scholarly journals Nonlinear optical imaging of single plasmonic nanoparticles with 30 nm resolution

2015 ◽  
Vol 17 (33) ◽  
pp. 21288-21293 ◽  
Author(s):  
Anke Horneber ◽  
Kai Braun ◽  
Jan Rogalski ◽  
Paul Leiderer ◽  
Alfred J. Meixner ◽  
...  
Keyword(s):  
Second Harmonic Generation ◽  
Optical Imaging ◽  
Optical Microscopy ◽  
Harmonic Generation ◽  
Nonlinear Optical ◽  
Second Harmonic ◽  
Near Field ◽  
Plasmonic Nanoparticles ◽  
Two Photon ◽  
Nonlinear Optical Imaging

Femtosecond-scanning near-field optical microscopy resolves the location-correlated second harmonic generation and two-photon photoluminescence from single nanoparticles with 30 nm resolution.

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