scholarly journals Treatment resistant postherpetic neuralgia - new treatments, better outcome

2020 ◽  
Vol 24 (4) ◽  
Author(s):  
Liliane Godinho ◽  
Margarida Anastcio ◽  
Ana Sofia Pereira ◽  
Maria Conceço Martins ◽  
Ana Valentim
Keyword(s):  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Persistent Pain ◽  
Treatment Resistant ◽  
Herpes Zoster Infection ◽  
Painful Condition ◽  
Infection Management ◽  
New Treatments

Postherpetic neuralgia (PHN) is a chronic and painful condition characterized by persistent pain following resolution of a Herpes zoster infection. Management of PHN can be challenging as this disorder is difficult to treat and many strategies have been described to reduce such pain.

scholarly journals Recurrent herpes zoster with segmental paresis and postherpetic neuralgia

2014 ◽  
Vol 71 (2) ◽  
pp. 214-217 ◽  
Author(s):  
Vesna Martic
Keyword(s):  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Complete Recovery ◽  
The Body ◽  
Chronic Lymphatic Leukemia ◽  
Virus Reactivation ◽  
Herpes Zoster Infection ◽  
Lymphatic Leukemia ◽  
Recurrent Herpes ◽  
Different Parts

Introduction. Postherpetic neuralgia and segmental paresis represent rare complications of herpes zoster infection. Recurrent herpes zoster is also rare and occurs within the first 3 years of the begining of the illness in only 1.4% of cases but it is generally higher in cases of chronic lymphatic leukemia (3.5%). Case report. We presented a patient with lymphatic leukemia who during the remission had 3 episodes of herpes zoster over a year. All of them took different parts of the body. One of these episodes was complicated by postherpetic neuralgia and segmental paresis. A complete recovery was seen in all the three episodes. Conclusion. As immunosuppression is one of mechanisms of virus reactivation, it is likely associated with the described rare complications of herpes zoster.

Effect of Cimetidine on Herpes Zoster Infection

1987 ◽  
Vol 21 (10) ◽  
pp. 803-805 ◽  
Author(s):  
László Bense ◽  
Jan A. Marcusson ◽  
Thomas Ramsten
Keyword(s):  
Herpes Zoster ◽  
Acute Pain ◽  
Postherpetic Neuralgia ◽  
Herpes Zoster Infection

Cimetidine was administered to two patients for herpes zoster infection. An acute pain-relieving effect was observed. The patients were followed for 11 and 14 months without developing postherpetic neuralgia. Possible mechanisms for prevention of postherpetic neuralgia by cimetidine are discussed.

scholarly journals Topical (S)-ketamine for pain management of postherpetic neuralgia

2012 ◽  
Vol 87 (3) ◽  
pp. 504-505 ◽  
Author(s):  
Guilherme Antonio Moreira de Barros ◽  
Hélio Amante Miot ◽  
Ademir Massarico Braz ◽  
Flávia Ramos ◽  
Marcos Aristoteles Borges
Keyword(s):  
Central Nervous System ◽  
Nervous System ◽  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Statistical Difference ◽  
Topical Administration ◽  
Herpes Zoster Infection ◽  
Pain Scores ◽  
Cutaneous Reactions ◽  
Prolonged Pain

Herpes zoster infection may cause postherpetic neuralgia, which is defined by prolonged pain predominantly mediated by central nervous system hypersensitivity. This phenomenon may be reversed by (S)-ketamine (SKET), but its use results in intolerable side effects, while its topical administration seems to be safe. It is a cross-over design study with 12 patients randomly divided into two groups. There was a significant effect of time on pain intensity, but no statistical difference in pain scores for SKET or placebo use in this sample in this treatment regimen. Only few mild cutaneous reactions were observed with topical SKET use.

scholarly journals Corticosteroids for Preventing Postherpetic Neuralgia After Herpes Zoster Infection

2019 ◽  
Vol 26 (6) ◽  
pp. 686-687
Author(s):  
Daniel S. Kowalsky ◽  
Allan B. Wolfson
Keyword(s):  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Herpes Zoster Infection

Effect of Ganoderma lucidum on Postherpetic Neuralgia

1998 ◽  
Vol 26 (03n04) ◽  
pp. 375-381 ◽  
Author(s):  
Yasuyo Hijikata ◽  
Seika Yamada
Keyword(s):  
Herpes Zoster ◽  
Postherpetic Neuralgia ◽  
Standard Therapy ◽  
Ganoderma Lucidum ◽  
Severe Pain ◽  
Dry Weight ◽  
Water Soluble ◽  
Hot Water ◽  
Herpes Zoster Infection

Administration of hot water soluble extracts of Ganoderma lucidum (GI) (36 to 72 g dry weight/day) decreased pain dramatically in two patients with postherpetic neuralgia recalcitrant to standard therapy and two other patients with severe pain due to herpes zoster infection.

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