ISOLATED BENZODIAZEPINE TOXICITY AND THE USE OF FLUMAZENIL: AN EYE-OPENING ANTIDOTE CASE REPORT IN A TERTIARY CARE HOSPITAL

2021 ◽  
pp. 231-233
Author(s):  
Siddharth Panikkar ◽  
Gigy Varkey Kuruttukulam ◽  
Manju Manmadhan ◽  
Jithin Antony Bose ◽  
Jacob Chacko ◽  
...  
Keyword(s):  
Case Report ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Delay In Diagnosis ◽  
Patient Medication ◽  
Common Causes ◽  
Eye Opening ◽  
Ct Brain ◽  
The 1960S

Since its debut in the 1960s, the broad use and availability of benzodiazepines has mirrored the increased incidence of overdose cases. Due to its non-specic presentation, there is often a delay in diagnosis. We report a case of Benzodiazepine toxicity in a 70-year-old man who presented to us in a comatose state. He was evaluated at another hospital initially and was intubated in view of his low Glasgow Coma scale. A CT brain plain study was done suspecting a basilar artery thrombus and he was referred to us for Neuro-Interventional procedures. As radiological, laboratory and electrophysiological investigations were unremarkable a provisional diagnosis of drug intoxication was made after patient medication review and a trial of Flumazenil was given, after which the patient had improved dramatically. Flumazenil is not routinely used due to fears of withdrawal seizures and its high cost. It also has no effect on reversing sedation caused by barbiturates, ethanol, or opioids. The antidote has a favorable risk-benet ratio when dosed appropriately and can be a helpful diagnostic tool after ruling out the more common causes of acute sensorium loss as demonstrated by this case report.

scholarly journals Postpartum TTP-HUS Syndrome: A Rare Autopsy Case Report in a Tertiary Care Hospital.

2017 ◽  
Vol 4 (3) ◽  
pp. C90-C93
Author(s):  
Ganesh R Kshirsagar ◽  
ChetanSudhakar Chaudhari ◽  
Prashant V Kumavat ◽  
Nikita Patel ◽  
Nitin M Gadgil
Keyword(s):  
Case Report ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Autopsy Case

scholarly journals Sphingomonas paucimobilis septicaemia in a tertiary care hospital in Nigeria: a case report

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
BASSEY EKENG ◽  
Rita Oladele ◽  
Chioma Osuagwu ◽  
Sunday Omisakin ◽  
Oluwadamilola Apanisile ◽  
...  
Keyword(s):  
Case Report ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Sphingomonas Paucimobilis ◽  
Care Hospital

scholarly journals The common causes leading to pancytopenia in patients presenting to tertiary care hospital

2013 ◽  
Vol 29 (5) ◽  
Author(s):  
Suneel Kumar ◽  
Kirpal Das Makheja ◽  
Bharat Kumar Maheshwari ◽  
Shafique Arain ◽  
Sangeeta Kumari ◽  
...  
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Common Causes ◽  
The Common

scholarly journals Management of self-inflicted oral organophosphate poisoning in adolescence - a case report

2021 ◽  
pp. 500-502
Author(s):  
Sattoju Nithish ◽  
Jagini Shiva Prasad ◽  
Aakaram Sujala ◽  
Endla Jagadish Kumar
Keyword(s):  
Case Report ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Gastric Lavage ◽  
Stable State ◽  
General Ward ◽  
Adolescent Male ◽  
Organophosphate Poisoning ◽  
Care Hospital ◽  
Seizure Episode

Organophosphate (OP) poisoning is more common in developing countries such as India. Here, we report a case of self-inflicted oral OP poisoning (monocrotophos) by an adolescent male patient who presented to the emergency department of a tertiary care hospital with tachycardia and frothing without seizure episode (non-linear presentation in OP poisoning). Based on the evidence of consumption of OP compound, the management of the patient went as planned and guarded with i.v. administration of pralidoxime and atropine. Gastric lavage was done soon after the patient came to the hospital and was admitted to the Intensive care unit for 5 days and in the general ward for the next 24 h. The patient was discharged from the hospital in a hemodynamically stable state after 6 days of hospital stay by managing the cardiac, muscarinic, and nervous system events as detailed in this case report.

scholarly journals Outcome in Normal Pressure Hydrocephalus after Ventriculoperitoneal Shunt in Tertiary Care Hospital

2021 ◽  
Vol 24 (4) ◽  
pp. 343-349
Author(s):  
Abdul Samad Panezai ◽  
Aurangzeb Kalhoro ◽  
Sher Hassan ◽  
Farrukh Javeed ◽  
Lal Rehman
Keyword(s):  
Normal Pressure Hydrocephalus ◽  
Ventriculoperitoneal Shunt ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Normal Pressure ◽  
Care Hospital ◽  
Vp Shunt ◽  
Excellent Outcome ◽  
Ct Brain ◽  
Biochemical Analyses

Objective:  To determine the outcome of the ventriculoperitoneal shunt in normal pressure hydrocephalus. Material and Methods:  This study was conducted at Jinnah Postgraduate Medical Centre, a tertiary care hospital in Karachi. Patients with idiopathic normal pressure hydrocephalus (NPH) were included. Gender distribution, presentation of symptoms and post-operative outcome based on the Stein Langfitt Scale were assessed. CSF was sent for microbiological and biochemical analyses. All patients were evaluated preoperatively and compared postoperatively during 6 months duration for improvement and any associated complication. Results:  In this study, we had 47 patients, 38 were male and 9 were female. 22 patients presented with dementia, 18 with urinary incontinence, 17 with gait disturbance 17, while 21 had headache based on Stein and Langfitt Scale. The 78.8% patients had an excellent outcome, 17% had a good outcome and 4.2% had poor results. Conclusion:  Ventriculoperitoneal (VP) shunt had promising results selected on history and examination of normal pressure hydrocephalus and improved radiological in Evan’s ratio CT brain scan. Keywords:  Normal Pressure Hydrocephalus (NPH), VP Shunt, Stein and Langfitt Scale.

scholarly journals Study of perinatal autopsies in tertiary care hospital 20 year experience

2017 ◽  
Vol 6 (7) ◽  
pp. 2914 ◽  
Author(s):  
N. S. Kamakeri ◽  
Ramalingappa C. A. ◽  
Vinayraju D.
Keyword(s):  
Congenital Abnormalities ◽  
Neonatal Period ◽  
Tertiary Care Hospital ◽  
Perinatal Death ◽  
Tertiary Care ◽  
Care Hospital ◽  
Pathological Findings ◽  
Meconium Aspiration ◽  
Perinatal Autopsy ◽  
Common Causes

Background: Losing a baby is painful. Looking for answers can help. Although nothing can change the loss, a perinatal autopsy may offer answers to better understand what happened. A perinatal autopsy is a medical exam done on the fetus or infant to help explain the cause of death. This exam may also find the underlying reason for an illness, disease or birth defect.Methods: Babies of mothers with bad obstetrics history, died in utero, neonatal period and baby deaths of unknown cause were subjected for clinical autopsy in the last 20 years. Based on the major and associated pathological findings, an attempt was made to find the cause of death.Results: Immaturity of the organs found to be the most common cause for perinatal death. Meconium aspiration pneumonia, external congenital abnormalities are found to be the other common causes for perinatal mortality.Conclusions: Perinatal autopsies are the effective method of finding the cause of perinatal death, and helps to some extent in preventing the future loses.

scholarly journals A study of surgical site infections in a tertiary care hospital

2019 ◽  
Vol 6 (11) ◽  
pp. 3911 ◽  
Author(s):  
Ayush Jain ◽  
Anuradha Tolpadi ◽  
Bhupendra Chaudhary ◽  
Ansh Chaudhary ◽  
Ankita Misra
Keyword(s):  
Nosocomial Infections ◽  
Antimicrobial Agents ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Laboratory Data ◽  
Surgical Site Infections ◽  
Health Concern ◽  
Care Hospital ◽  
Duration Of Surgery ◽  
Common Causes

Background: Health care-associated infections remain as an important public health concern. Surgical site infections (SSIs) are known to be one of the most common causes of nosocomial infections worldwide.Methods: A prospective observational study was conducted across 12 months (May 2018-April 2019) in a tertiary care hospital. The present study includes 223 patients who were undergoing clean and clean contaminated surgery in the hospital. Contaminated and dirty surgeries were excluded. The demographic data of the patient, diagnostic criteria used, associated risk factors, use of prophylactic antimicrobial agents, the type and duration of surgery, clinical evaluation of wound and laboratory data was collected. All the pus samples or wound swabs of clinically suspects of SSI cases received in the Department of Microbiology were inoculated and interpreted according to Centre for Disease Control and Infection guidelines.Results: The study included 223 patients who underwent surgery in the hospital. Amongst them 9 (4%) developed SSI. The incidence of SSI was 4.03%. There was a direct relationship observed between the occurrence of SSI and certain co-morbid conditions such as diabetes. It was also observed that prolonged surgeries above two hours and females were more predisposed to develop a surgical site infection.Conclusions: SSIs being one of the most common causes of nosocomial infections. It was also the most important factor responsible for significant morbidity, mortality, unwanted prolonged hospitalization and additional cost of treatment in surgical patients which can be reduced by strictly following the guidelines of infection control along with judicious and rational use of antibiotics.

scholarly journals HAFNIA ALVEI BACTEREMIA FOLLOWING BRONCHOPNEUMONIA IN AN ELEVEN MONTH OLD CHILD: A CASE REPORT FROM A TERTIARY CARE HOSPITAL IN NEPAL

2018 ◽  
Vol 1 (2) ◽  
pp. 22-25 ◽  
Author(s):  
Niranjan Nayak ◽  
Nisha Baral ◽  
Rajani Shrestha ◽  
Ranjana Parajuli ◽  
Deependra Hamal ◽  
...  
Keyword(s):  
Case Report ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital ◽  
Hafnia Alvei
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