MULTI-MODALITY IMAGING OF SALIVARY GLAND TUMORS

Background: Imaging of salivary gland tumors is a challenge for the radiologist due to varied histological features and overlapping clinical presentation.The salivary glands have a glandular structure with tubules, secretory acini and myoepithelial cells to produce and secrete saliva. They are divided into two types: major and minor. Parotid, submandibular, and sublingual glands are the major paired salivary glands of the body. Multiple small minor salivary glands are distributed in the upper aerodigestive tract including PNS & parapharyngeal spaces. Objective: This study evaluates the role of different modalities used to assess salivary gland tumors. Results: 50 patients presenting with suspected salivary gland masses were evaluated. 22 males and 28 females were assessed with age ranging from 15 to 66 years (mean age of 52 years). 27 cases were of pleomorphic adenoma, 10 warthin tumors, 2 intraductal papilloma,1 lipoma, 1 oncocytoma,1 intra parotid paraganglioma, 2 hemangioma, 3 muco-epidermoid carcinoma, 2 adeno cystic cancer and 1 acinic cell cancer of salivary gland. 90% of patients (45 out of 50) presented with swelling / lump. 26% of patients had pain /discomfort and 4% of patients (2 out of 50) had facial nerve palsy. Conclusion: The conventional radiological evaluation was carried out using Xray and ultrasound with USG as rst line of investigation.. Cross sectional imaging with CT and MRI is useful in assessing for local extension , invasion of neighbouring structures as well as lymph nodal and systemic metastasis.MRI is superior to CT in assesing for extent and perineural spread.

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Epidemiologic Characteristics of Salivary Gland Tumors in an Iranian Population

Shiraz E-Medical Journal ◽

10.5812/semj.107675 ◽

2021 ◽

Vol In Press (In Press) ◽

Author(s):

Nafise Shamloo ◽

Alireza Ghanadan ◽

Fahimeh Sadat Hashemian ◽

Maedeh Ghorbanpour

Keyword(s):

Salivary Gland ◽

Adenoid Cystic Carcinoma ◽

Salivary Glands ◽

Pleomorphic Adenoma ◽

Malignant Tumors ◽

The Body ◽

Salivary Gland Tumors ◽

Benign Tumors ◽

Cross Sectional ◽

Adenoid Cystic

Background: Salivary gland tumors include a wide variety of benign and malignant tumors in the oral and maxillofacial region. Although these tumors are not common, they are not rare. The prevalence of these tumors varies with regard to age, gender, and their location in the body. Objectives: This study aimed to evaluate the frequency of benign and malignant salivary gland tumors in patients referred to three referral hospitals in Tehran, Iran. Methods: This retrospective cross-sectional study examined the demographic and pathologic records of the patients with salivary gland tumors submitted to the Department of Pathology of Amir Alam, Loghman Hakim, and Shohada Hospitals from 2005 to 2016. In this study, the histological variants of salivary gland tumors and clinical parameters such as age, gender, and the location of the tumor were examined. The clinical data were analyzed using SPSS software version 21. Results: Of 137632 patient records, 1180 cases were salivary gland tumors. Pleomorphic adenoma in 794 cases (67.3%) and adenoid cystic carcinoma in 109 cases (9.2%) were the most common tumors, respectively. Salivary gland tumors were more common in males, and the participants’ mean age was 42.86 ± 16.5 years. The most common site was parotid and minor salivary glands, with 937 (79.4%) and 137 (12%) cases, respectively. Conclusions: In this study, the most common benign tumor was pleomorphic adenoma in the parotid gland, and the most common malignant tumor was adenoid cystic carcinoma in the major salivary glands. Furthermore, benign tumors were more frequent than malignant tumors.

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Role of myoepithelial cells in the development of salivary gland tumors

Cancer ◽

10.1002/1097-0142(197105)27:5<1255::aid-cncr2820270533>3.0.co;2-1 ◽

1971 ◽

Vol 27 (5) ◽

pp. 1255-1261 ◽

Cited By ~ 117

Author(s):

G. Hübner ◽

H. J. Klein ◽

O. Kleinsasser ◽

H. G. Schiefer

Keyword(s):

Salivary Gland ◽

Myoepithelial Cells ◽

Salivary Gland Tumors

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Participation and role of myoepithelial cells in benign and malignant salivary gland tumors

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/s0901-5027(97)81603-7 ◽

1997 ◽

Vol 26 ◽

pp. 257

Author(s):

H. Harada ◽

M. Morimatsu

Keyword(s):

Salivary Gland ◽

Myoepithelial Cells ◽

Salivary Gland Tumors ◽

Malignant Salivary Gland Tumors

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Myoepithelioma

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348948509400523 ◽

1985 ◽

Vol 94 (5) ◽

pp. 523-524 ◽

Cited By ~ 62

Author(s):

John G. Batsakis

Keyword(s):

Salivary Gland ◽

Salivary Glands ◽

Benign Lesion ◽

Myoepithelial Cells ◽

Salivary Gland Tumors ◽

Mixed Tumor ◽

Rare Form

Myoepithelial cells are integral components of normal salivary glands. Their active or passive participation in the histogenesis of several salivary gland tumors is a debated issue. This debate notwithstanding, a rare form of salivary tumor composed entirely of myoepithelial cells exists and probably represents a monomorphic form of mixed tumor. This tumor, the myoepithelioma occurs in most major and minor salivary tissues and is generally a biologically benign lesion.

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Identification of Root Cause Failure in Silicon on Insulator Body Contacted nFETs Using Scanning Capacitance Microscopy and Scanning Spreading Resistance Microscopy

ISTFA 2006: Conference Proceedings from the 32nd International Symposium for Testing and Failure Analysis ◽

10.31399/asm.cp.istfa2006p0102 ◽

2006 ◽

Author(s):

J.S. McMurray ◽

C.M. Molella

Keyword(s):

The Body ◽

Silicon On Insulator ◽

Back Side ◽

Cross Sectional ◽

Plan View ◽

Spreading Resistance ◽

Scanning Capacitance Microscopy ◽

Root Cause ◽

Cross Sectional Imaging ◽

Active Channel

Abstract Root cause for failure of 90 nm body contacted nFETs was identified using scanning capacitance microscopy (SCM) and scanning spreading resistance microscopy (SSRM). The failure mechanism was identified using both cross sectional imaging and imaging of the active silicon - buried oxide (BOX) interface in plan view. This is the first report of back-side plan view SCM and SSRM data for SOI devices. This unique plan view shows the root cause for the failure is an under doped link up region between the body contacts and the active channel of the device.

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Of the Movement of Worms

Journal of Experimental Biology ◽

10.1242/jeb.27.1.29 ◽

1950 ◽

Vol 27 (1) ◽

pp. 29-39 ◽

Cited By ~ 2

Author(s):

GARTH CHAPMAN

Keyword(s):

Hydrostatic Pressure ◽

Closed System ◽

Body Fluid ◽

The Body ◽

Cross Sectional ◽

Working Length ◽

Cylindrical Form ◽

Maximum Thrust

Four aspects of the functioning of a fluid-filled cylindrical animal have been examined, viz.: (I) the role of the body fluid as a skeleton for the interaction of the longitudinal and circular muscles of which the animal must be composed; (2) the measurement of the maximum thrust which the animal can exert by measurement of its internal hydrostatic pressure; (3) the application of the force to the substratum and the part played by friction; (4) the relation between the changes in dimensions of the animal and the working length of the muscles. Under (1) the necessity for a longitudinal and circular construction has been shown and the necessity for a closed system emphasized. Under (2) the pressure exerted on the body fluid by the contraction of the longitudinal and circular muscles is discussed, and from their cross-sectional areas it is shown to be probable that when contracting maximally in Lumbricus they are not balanced, but that the longitudinals are about ten times as strong as the circulars. Under (3) it is shown that the strength of an animal as measured by its internal hydrostatic pressure is sufficient to account for its customary activities. Use which may be made of the longitudinals during burrowing is pointed out. Under (4) it is shown to be mechanically sound for burrowing animals of cylindrical form to be ‘fat’, but that a ‘thin’ animal is more efficient at progression.

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Immunohistochemical expression of vimentin, calponin and HHF-35 in salivary gland tumors

Brazilian Dental Journal ◽

10.1590/s0103-64402007000300003 ◽

2007 ◽

Vol 18 (3) ◽

pp. 192-197 ◽

Cited By ~ 9

Author(s):

Roberta Barroso Cavalcante ◽

Fernanda Ferreira Lopes ◽

Andréa Soares Ferreira ◽

Roseana de Almeida Freitas ◽

Lélia Batista de Souza

Keyword(s):

Salivary Gland ◽

Myoepithelial Cells ◽

Salivary Gland Tumors ◽

Low Grade ◽

Tubular Structures ◽

Immunohistochemical Markers ◽

Adenoid Cystic ◽

Peripheral Cells ◽

Diffuse Distribution ◽

Labeling Pattern

Myoepithelial cells present a complex immunophenotype, with the expression of proteins varying according to the stage of normal or neoplastic differentiation of the cell. In order to evaluate the immunohistochemical markers expressed by these cells, a panel of antibodies composed of vimentin, calponin and HHF-35 was applied to 28 salivary gland tumors. The results demonstrated a higher percent sensitivity of vimentin and calponin compared to HHF-35. However, calponin and HHF-35 presented a focal labeling pattern in contrast with the diffuse distribution of vimentin. The cells predominantly stained by all tested antibodies included nonluminal cells in duct-like and tubular structures, such as those seen in pleomorphic adenomas and adenoid cystic carcinomas, as well as cells in the cords and nests of polymorphous low-grade adenocarcinomas and peripheral cells of sheets and nests of myoepitheliomas. In conclusion, the combination of calponin and vimentin is suggested for the identification of myoepithelial cells in salivary gland tumors.

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