scholarly journals High Performance CNTENFET with K/PPy/CNT nanocomposite biosensing layer for Cholesterol Detection

2021 ◽  
Author(s):  
Gaurav Keshwani ◽  
Jiten Chandra Dutta
Keyword(s):  
Carbon Nanotube ◽  
High Performance ◽  
Field Effect Transistor ◽  
High Selectivity ◽  
Dynamic Range ◽  
Device Performance ◽  
Wide Dynamic Range ◽  
Cholesterol Detection ◽  
Dual Gate ◽  
Effect Transistor

We have reported a high-performance dual gated carbon nanotube enzyme modified field-effect transistor (CNT-ENFET) for cholesterol detection. To improve the device performance, we have used dual-gate design with high κ dielectric as top gate and low κ dielectric as bottom gate and a nanocomposite of potassium doped carbon nanotube with polypyrrole (K/PPy/CNT) as the biosensing membrane. The device exhibited a good sensitivity (~1.0 V/decade), low response time (~1 s), wide dynamic range (0.1 - 25) mM, wide linear range (2-20 mM), low detection limit (0.11 mM), good stability (7 months) and high selectivity (interference ~1.8 %).

High Performance CNTENFET with K/PPy/CNT nanocomposite biosensing layer for Cholesterol Detection

2021 ◽  
Author(s):  
Gaurav Keshwani ◽  
Jiten Chandra Dutta
Keyword(s):  
Carbon Nanotube ◽  
High Performance ◽  
Field Effect Transistor ◽  
High Selectivity ◽  
Dynamic Range ◽  
Device Performance ◽  
Wide Dynamic Range ◽  
Cholesterol Detection ◽  
Dual Gate ◽  
Effect Transistor

We have reported a high-performance dual gated carbon nanotube enzyme modified field-effect transistor (CNT-ENFET) for cholesterol detection. To improve the device performance, we have used dual-gate design with high κ dielectric as top gate and low κ dielectric as bottom gate and a nanocomposite of potassium doped carbon nanotube with polypyrrole (K/PPy/CNT) as the biosensing membrane. The device exhibited a good sensitivity (~1.0 V/decade), low response time (~1 s), wide dynamic range (0.1 - 25) mM, wide linear range (2-20 mM), low detection limit (0.11 mM), good stability (7 months) and high selectivity (interference ~1.8 %).

Characterization of device performance and reliability of high performance Ge-on-Si field-effect transistor

2011 ◽  
Vol 88 (12) ◽  
pp. 3424-3427 ◽  
Author(s):  
Won-Ho Choi ◽  
Jungwoo Oh ◽  
Ook-Sang Yoo ◽  
In-Shik Han ◽  
Min-Ki Na ◽  
...  
Keyword(s):  
Field Effect ◽  
High Performance ◽  
Field Effect Transistor ◽  
Device Performance ◽  
Effect Transistor

scholarly journals Comparison of Duplex and Quadruplex Folding Structure Adenosine Aptamers for Carbon Nanotube Field Effect Transistor Aptasensors

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2280
Author(s):  
Hong Phan T. Nguyen ◽  
Thanihaichelvan Murugathas ◽  
Natalie O. V. Plank
Keyword(s):  
Carbon Nanotube ◽  
Field Effect ◽  
High Performance ◽  
Field Effect Transistor ◽  
Dissociation Constants ◽  
High Sensitivity ◽  
Quadruplex Structure ◽  
G Quadruplex ◽  
Effect Transistor ◽  
Folding Structure

Carbon nanotube field effect transistor (CNT FET) aptasensors have been investigated for the detection of adenosine using two different aptamer sequences, a 35-mer and a 27-mer. We found limits of detection for adenosine of 100 pM and 320 nM for the 35-mer and 27-mer aptamers, with dissociation constants of 1.2 nM and 160 nM, respectively. Upon analyte recognition the 35-mer adenosine aptamer adopts a compact G-quadruplex structure while the 27-mer adenosine aptamer changes to a folded duplex. Using the CNT FET aptasensor platform adenosine could be detected with high sensitivity over the range of 100 pM to 10 µM, highlighting the suitability of the CNT FET aptasensor platform for high performance adenosine detection. The aptamer restructuring format is critical for high sensitivity with the G-quadraplex aptasensor having a 130-fold smaller dissociation constant than the duplex forming aptasensor.

Sign in / Sign up

Export Citation Format

Share Document