THE ROLE OF PERIPLASMIC CHAPERONS IN FORMATION OF REDUCED SENSITIVITY OF THE GONOCOCCUS TO BROAD-SPECTRUM ANTIBIOTICS

Author(s):  
I.N. Bodoev ◽  
◽  
M.V. Malahova ◽  
O.V. Pobeguts ◽  
I.O. Butenko ◽  
...  
2020 ◽  
Vol 158 (6) ◽  
pp. S-1110-S-1111
Author(s):  
Jae Gon Lee ◽  
Jin Hwa Park ◽  
Chan Hyuk Park ◽  
Chang Soo Eun ◽  
Dong Soo Han ◽  
...  

1957 ◽  
Vol 106 (1) ◽  
pp. 1-14 ◽  
Author(s):  
Alexander M. Rutenburg ◽  
Edmund Sonnenblick ◽  
Irving Koven ◽  
H. Arto Aprahamian ◽  
Leopold Reiner ◽  
...  

Diffuse hepatic cirrhosis develops in rats on a choline-deficient diet within 300 days. Absorbable broad spectrum antibiotics added to the daily diet do not prevent the development of fatty infiltration, but they delay the development of cirrhosis for about 100 days more. Non-absorbable antibiotics added to the daily diet prevent the development of cirrhosis in most rats for as long as 750 days. The superiority of non-absorbable antibiotics to absorbable antibiotics excludes a systemic effect of the antibiotics and demonstrates that intestinal bacteria are largely, if not wholly, responsible for the cirrhosis in rats on a choline-deficient diet.


2003 ◽  
Vol 20 (64) ◽  
pp. 19-24
Author(s):  
Pushpa Raj Sharma

50 patients with chest infections admitted in the Kanti Childrens Hospital were studied to assess the effectiveness of the broad spectrum antibiotics in altering the course of the disease. These infants were graded to assess the daily improvement in their conditions and were followed up to 7 days. Altogether 12 patients were grouped in grade 2 and 38 were grouped in grade 1. There were no change in the condition of these patients up to the fifth day of admision inspite of the costly drugs used.These findings confirm that routine use of antibiotics in chest infections in infants without secondary complications does not alter the prognosis. Moreover it increases the economic burden to family whose daily income can hardly afford nutretious diet.


2020 ◽  
Vol 16 (4) ◽  
pp. 455-461
Author(s):  
Gabriela M. Baia ◽  
Otniel Freitas-Silva ◽  
Murillo F. Junior

Fruits and vegetables are foods that come into contact with various types of microorganisms from planting to their consumption. A lack or poor sanitation of these products after harvest can cause high losses due to deterioration and/ or pathogenic microorganisms. There are practically no post-harvest fungicides or bactericides with a broad spectrum of action that have no toxic residual effects and are safe. However, to minimize such problems, the use of sanitizers is an efficient device against these microorganisms. Chlorine is the most prevalent sanitizing agent because of its broad spectrum, low cost and well-established practices. However, the inevitable formation of disinfection by-products, such as trihalomethanes (THMs) and haloacetic acids (HAAs), is considered one of the main threats to food safety. Alternative sanitizers, such as chlorine dioxide (ClO2) and ozone, are becoming popular as a substitute for traditional post-harvest treatments. Thus, this review addresses the use of chlorine, chlorine dioxide and ozone emphasizing aspects, such as usage, safe application, spectrum of action and legislation. In order to ensure the quality and safety of final products, the adoption of well-prepared sanitation and sanitation programs for post-harvest fruits and vegetables is essential.


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