scholarly journals The role of echocardiography in prognosis and clinical complication risk prediction in patients with acute pulmonary embolism

2016 ◽  
Vol 15 (1) ◽  
pp. 8-16
Author(s):  
David Vindiš ◽  
Martin Hutyra ◽  
Jan Přeček ◽  
Daniel Šaňák ◽  
Michal Král ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Risk Prediction ◽  
Acute Pulmonary Embolism ◽  
Clinical Complication ◽  
Complication Risk

Diagnosing and managing acute pulmonary embolism: role of cardiac troponins

2003 ◽  
Vol 145 (5) ◽  
pp. 751-753 ◽  
Author(s):  
Victor F. Tapson
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Cardiac Troponins

Initial Treatment of Pulmonary Embolism

2007 ◽  
Vol 6 (3) ◽  
pp. 95-101
Author(s):  
Alastair Proudfoot ◽  
◽  
Helen Yarranton ◽  
Simon Gibbs ◽  
Derek Bell ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Initial Treatment ◽  
Acute Pulmonary Embolism ◽  
Inferior Vena ◽  
Previous Article ◽  
Diagnostic Approach ◽  
Inferior Vena Caval ◽  
Common Presentation ◽  
In Pregnancy

Acute pulmonary embolism (PE) is a common presentation on the acute medical take. In our previous article in Vol 6 issue 1 we discussed the diagnostic approach to this condition. This article concentrates on the treatment of PE, including guidance for treatment of PE in pregnancy and cancer. This article also discusses the role of alternative anticoagulants, thrombolysis, surgery and inferior vena caval filters.

scholarly journals Role of echocardiography in acute pulmonary embolism.

1989 ◽  
Vol 30 (5) ◽  
pp. 655-664 ◽  
Author(s):  
Shumpei OKUBO ◽  
Kunio MIYATAKE ◽  
Seiki NAGATA ◽  
Norifumi NAKANISHI ◽  
Takao YOSHIOKA ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism

Involvement of Rho kinase in the pathogenesis of acute pulmonary embolism-induced polystyrene microspheres in rats

2010 ◽  
Vol 298 (3) ◽  
pp. L297-L303 ◽  
Author(s):  
M. Toba ◽  
T. Nagaoka ◽  
Y. Morio ◽  
K. Sato ◽  
K. Uchida ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Acute Pulmonary Embolism ◽  
Kinase Inhibitors ◽  
Systolic Pressure ◽  
Rho Kinase ◽  
Arterial Oxygen Tension ◽  
Arterial Oxygen ◽  
Polystyrene Microspheres ◽  
Ventricular Systolic Pressure

Acute pulmonary embolism (PE) is a life-threatening disease, and several vasoconstrictors, including endothelin-1 (ET-1), play a key role in vasoconstriction and hypoxemia during the development of PE. Rho kinase is activated by various vasoconstrictors resulting in vascular contraction and remodeling. Recent evidence has revealed an important role of Rho kinase in the pathogenesis of systemic and pulmonary vascular diseases. However, contribution of Rho kinase in PE remains unclear. We thus investigated the role of Rho kinase in the PE rat model induced by intrajugular administration of polystyrene microspheres (mean diameter, 26 μm). At 6 h following the administration of microspheres (1.5 ml/kg), right ventricular systolic pressure (RVSP) was higher in the PE than in the control rats (15.8 ± 1.6 vs. 32.9 ± 7.5 mmHg). Arterial oxygen tension was lower (92.3 ± 12.5 vs. 66.0 ± 17.7 Torr), and alveolar-arterial difference in oxygen partial pressure was higher (3.9 ± 3.8 vs. 36.5 ± 26.9 Torr) in the PE rats. Western blotting analysis revealed upregulation and downregulation in expression of vascular cell adhesion molecule-1 and endothelial nitric oxide synthase in lungs from the PE rats, respectively, and radioimmunoassay demonstrated an increase in plasma ET-1 levels. Lung Rho kinase α expression was greater in the PE rats. At 5 h following administration of microspheres (0.75 ml/kg), intravenous Rho kinase inhibitors HA1077 and Y27632 (3 mg/kg each) attenuated elevation of RVSP (22.0 ± 3.7, 17.1 ± 3.2, 14.3 ± 2.6 mmHg, PE, PE+HA1077, PE+Y27632) and the severity of hypoxemia (66.3 ± 16.2, 94.9 ± 23.0, 89.1 ± 8.5 Torr, PE, PE+HA1077, PE+Y27632) in the PE rats. These results suggest that pulmonary endothelial dysfunction and activation of Rho kinase may contribute to the potentiation of vasoconstriction and hypoxemia in the PE rats.

Short- and long-term prognostic role of diastolic blood pressure in intermediate-high risk patients with acute pulmonary embolism

2018 ◽  
Vol 55 ◽  
pp. e23-e24
Author(s):  
Marco Zuin ◽  
Gianluca Rigatelli ◽  
Pietro Zonzin ◽  
Franco Casazza ◽  
Loris Roncon
Keyword(s):  
Blood Pressure ◽  
Pulmonary Embolism ◽  
High Risk ◽  
Diastolic Blood Pressure ◽  
Acute Pulmonary Embolism ◽  
Prognostic Role ◽  
Risk Patients ◽  
Short And Long Term

Severity assessment of acute pulmonary embolism: Role of CT angiography

2005 ◽  
Vol 40 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Gilbert R. Ferretti ◽  
Delphine Collomb ◽  
Jean Noel Ravey ◽  
Gerald Vanzetto ◽  
Max Coulomb ◽  
...  
Keyword(s):  
Pulmonary Embolism ◽  
Ct Angiography ◽  
Acute Pulmonary Embolism ◽  
Severity Assessment

scholarly journals Current Endovascular Treatment Options in Acute Pulmonary Embolism

2021 ◽  
Vol 11 ◽  
pp. 5
Author(s):  
Kelli Moore ◽  
Jeff Kunin ◽  
Mohammed Alnijoumi ◽  
Prashant Nagpal ◽  
Ambarish P. Bhat
Keyword(s):  
Pulmonary Embolism ◽  
Endovascular Treatment ◽  
Acute Pulmonary Embolism ◽  
Treatment Options ◽  
Mortality And Morbidity ◽  
Response Team ◽  
Promising Treatment ◽  
Level I ◽  
Acute Pe

Acute pulmonary embolism (PE) is a significant cause of mortality and morbidity across the globe. Over the last few decades, there have been major therapeutic advances in acute PE management, including catheter-based therapy. However, the effectiveness of catheter-based therapy in acute PE is not supported by Level I evidence, making the use of this promising treatment rather controversial and ambiguous. In this paper, we discuss the risk stratification of acute PE and review the medical and endovascular treatment options. We also summarize and review the data supporting the use of endovascular treatment options in acute PE and describe the potential role of the PE response team.

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