Cybersecurity Incident Response and Management

This chapter presents a systematic literature review on best practices regarding cybersecurity incident response handling and incident management. The study identifies incident handling models that are used worldwide when responding to any type of cybersecurity incident. The authors highlight the importance of understanding the current cyber threat landscape in any incident response team and their standard operations procedures. The chapter provides guidelines for building a cybersecurity incident team in terms of incident categorization, capabilities, tasks, incident cost calculation, and metrics.

Effectiveness of Rapid Response Team on In-hospital Mortality in Patients with Hematologic Malignancy

Purpose: Patients with hematologic malignancy (HM) typically have a high mortality rate when their condition deteriorates. The chronic progressive course of the disease makes it difficult to assess the effect of intervention on acute events. We investigated the effectiveness of a rapid response team (RRT) on in-hospital mortality in patients with HM.Methods: We retrospectively analyzed the data of patients with HM who admitted to the medical intensive care unit between 2006 and 2015. Clinical outcomes before and after RRT implementation were evaluated.Results: A total of 228 patients in the pre-RRT period and 781 patients in the post-RRT period were included. The overall in-hospital mortality was 55.4%. Patients in the post-RRT period had improved survival; however, they required more vasopressor therapy, continuous renal replacement therapy, and extracorporeal membrane oxygenation. Multivariate analysis revealed that in-hospital mortality was associated with RRT activation (hazard ratio [HR], 0.634; 95% confidence interval [CI], 0.498–0.807; p < .001), neurological disease (HR, 2.007; 95% CI, 1.439–2.800; p < .001), sequential organ failure assessment score (HR, 1.085; 95% CI, 1.057–1.112; p < .001), need for continuous renal replacement therapy (HR, 1.608; 95% CI, 1.206–1.895; p< .001), mechanical ventilation (HR, 1.512; 95% CI, 1.206–1.895; p< .001), vasopressor (HR, 1.598; 95% CI, 1.105–2.311; p = .013), and extracorporeal membrane oxygenation (HR, 1.728; 95% CI, 1.105–2.311; p = .030).Conclusion: RRT activation may be associated with improved survival in patients with HM.