scholarly journals Frequency of Post-Operative Hypotony in 23 Gauge and 25 Gauge Pars Plana Vitrectomy in Advanced Diabetic Eye Disease

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Hussain Ahmad Khaqan ◽  
Usman Imtiaz ◽  
Hasnain Muhammad Buksh ◽  
Hafiz Ateeq Ur Rehman ◽  
Raheela Naz

Purpose:  To compare the frequency of post-operative hypotony between 23G PPV and 25G PPV in advanced diabetic eye disease. Study Design:  Quasi experimental study. Place and Duration of Study:  Study was conducted at department of Ophthalmology, Lahore General Hospital, Lahore from 7th April 2016 to 6th October 2016. Methods:  Total 100 cases of advanced diabetic eye disease with age ranging from 25 – 65 years and either gender were selected. Patients with nystagmus and claustrophobia, lamellar macular holes, epiretinal membrane and neovascular glaucoma were excluded. Patients were divided by lottery method into 2 groups. Data of the patient i.e. name, age, sex, patient’s registration number and address was recorded. Every patient had detailed preoperative work-up; including best corrected visual acuity by Snellen’s chart, intraocular pressure by applanation tonometer, indirect ophthalmoscopy and B-scan for retinal status. Group A underwent 23G PPV and group B underwent 25G PPV. Patients were followed after 24 hours of surgery to measure intraocular pressure to access hypotony. Results:  Mean age of patients in group A was 50.16 ± 10.40 years and in group B was 50.26 ± 9.91 years. Out of 100 patients 57 (57.0%) were females and 43 (43.0%) were males, with female to male ratio of 1.1:1. Post-operative hypotony was seen in 24 (48.0%) patients with 23G PPV and 02 (4.0%) patients with 25G PPV (p-value = 0.0001). Conclusion:  This study concluded that the frequency of post-operative hypotony in 23G Pars Plana Vitrectomy was higher as compared to 25G Pars Plana Vitrectomy in advanced diabetic eye disease. Key Words:  Diabetic retinopathy, Pars Plana Vitrectomy, Hypotony.

2020 ◽  
Vol 36 (4) ◽  
Author(s):  
Ambreen Gull ◽  
Sairam Ahmad ◽  
Fuad Ahmad Khan Niazi ◽  
Ali Raza

Purpose:  To find out the clinical outcome of Pars Plana Vitrectomy with and without Intravitreal Bevacizumab as a pretreatment in advanced diabetic eye disease. Place and Duration of Study:  Ophthalmology department of holy family hospital Rawalpindi, from January 2018 to December 2018. Methods:  Sixty patients with advanced proliferative diabeticretinopathy wereincluded. Patients were divided into two groups. In group A, patients had pars plana vitrectomy with pre procedure injection of intravitreal Bevacizumab and group B had vitrectomy without pre procedure intravitreal Bevacizumab. Amount of bleeding during vitrectomy, surgical time and rate of iatrogenic tears were noted in both groups. Outcome measures were post operative best corrected visual acuity at 6 months and post operative recurrent vitreous hemorrhage. Results:  Patients had a mean age of 63.83 ± 7.314. In group A, mild bleeding was seen in 33%, moderate in 6.7% and severe in 0%. In group B, mild bleeding was seen in 13.3%, moderate in 46.7%, and severe bleeding in 40%. After 6 months, 27 (90%) patients in group A showed improvement in best corrected visual acuity while it was seen in 12 (40%) patients in group B. Iatrogenic tearswere seen in 10% in group A and 36% in group B. Mean time of surgery in group A was 59.27 ± 6.823 minutes and in group B was 77.87 ± 9.637 minutes. Rate of recurrent vitreous hemorrhage after vitrectomy was 6.7% in group A and 40% in group B. Conclusion:  Intravitreal injection of Bevacizumab is helpful in reducing surgical time and also decreases intraoperative and post operative bleeding. Key Words:  Bevacizumab, Vitrectomy, Proliferative Diabetic Retinopathy.


2021 ◽  
pp. 112067212110576
Author(s):  
Stanislao Rizzo ◽  
Lorenzo de Angelis ◽  
Francesco Barca ◽  
Daniela Bacherini ◽  
Lorenzo Vannozzi ◽  
...  

Purpose To assess the occurrence of peripheral vitreoschisis-induced vitreous cortex remnants (p-VCRs) in primary rhegmatogenous retinal detachment (RD) and investigate whether the presence of p-VCRs results in a greater risk of RD recurrence, secondary to Proliferative Vitreoretinopathy (PVR) development after pars plana vitrectomy (PPV). Methods Patients who underwent PPV for primary rhegmatogenous RD between January 2016 and December 2018 were included. The presence of residual p-VCRs was confirmed intraoperatively using triamcinolone acetonide (TA). Patients with p-VCRs were divided into two groups: Group A comprised of patients who underwent PPV without p-VCR removal, while Group B included patients who underwent PPV with p-VCR removal. Results Four hundred-thirteen eyes with evidence of p-VCR were analyzed. Two-hundred-twenty-three eyes underwent PPV without VCR removal (Group A), while 190 eyes underwent PPV with p-VCR removal (Group B). Primary anatomical success was 91.5% in the Group A and 95.4% in the group B. Retinal re-detachment due to PVR occurred in 17 (7.6%) eyes in Group A and in four (2.1%) eyes in Group B within the first 3 months (p  =  0.01). Among group A, in 11 eyes, there was a diffuse posterior PVR grade C, while six eyes were focal PVR grade C. In Group B, we observed four retinal re-detachment due to focal PVR grade C. Conclusion The presence of p-VCRs seems to be associated with a higher incidence of PVR development and might also result in more complex RD recurrence, this suggests the need for more aggressive VCRs removal during the first surgery.


2021 ◽  
Vol 6 (1) ◽  
pp. e000605 ◽  
Author(s):  
Koichi Nishitsuka ◽  
Katsuhiro Nishi ◽  
Hiroyuki Namba ◽  
Yutaka Kaneko ◽  
Hidetoshi Yamashita

ObjectiveTo evaluate the technique of peripheral vitreous shaving during vitrectomy, we measured the residual peripheral vitreous using intraoperative optical coherence tomography (iOCT).Methods and AnalysisThis retrospective study included 44 eyes that underwent 25-gauge pars plana vitrectomy with iOCT by a single surgeon. In all cases, the surgery was performed via ocular indentation. Cases in group A were treated with vitreous shaving under slit lamp microscope illumination, whereas cases in group B were treated with vitreous shaving under a wide-angle viewing system. Residual peripheral posterior vitreous-cortex detachment (PVD) was quantified by iOCT.ResultsiOCT image analysis enabled the visualisation of the angle formed between the retina and peripheral PVD around the vitreous base in all cases. After the completion of vitreous shaving, the mean length of the peripheral PVD was shorter in group A (961.7±214.7 µm) compared with group B (1925.3.7 ± 626.1 µm; p<0.01).ConclusioniOCT enabled the quantification of the residual peripheral vitreous after vitreous shaving. The quantification of the residual peripheral vitreous after different shaving procedures will be important for advocating appropriate vitreous shaving in future.


2019 ◽  
Vol 35 (3) ◽  
Author(s):  
Afia Matloob Rana ◽  
Ali Raza ◽  
Waseem Akhter

ABSTRACT: Introduction: Cataract affects a huge population around the globe and equally affects Pakistani population. Children with congenital cataract presents with huge deformity and dependence, the consequences are lifelong if not treated with better management at right time. In this study we aimed at comparing intracameral and subcojunctival injection of dexamethasone in congenital cataract in terms of postoperative inflammation. Purpose: The purpose of our study is comparing the role of intracameral injection with subconjunctival injection of dexamethasone in preventing immediate postoperative inflammation after congenital cataract extraction and to make the ground for better option for programmatic implementation in these cases. Study Design: Randomized control trial Place and duration of study: Holy Family Hospital, Rawalpindi since june 2014 to May 2015. Material and methods: In this RCT, 190 children with congenital cataract were enrolled in the department of ophthalmology, Holy Family Hospital, Rawalpindi. Patients were selected using a random table, 95 cases each in intracameral injection and subconjunctival injection of dexamethasone groups.The study duration was one year from june 2014 to May 2015. Ethical approval was granted by hospital ethics committee and patients were administered a written informed consent at enrolment. The outcome measure was intraocular inflammation after surgery for extraction of cataract. Results: Male cases were in majority in group B (58.9%) whereas in group A females (55.8%) were in majority. Mean age was6.43 ± 4.69 years in Group-A compared to 5.85 ± 4.10 years in Group-B. Frequency of posterior synechiae (inflammation) was 4.21% (n=4) in Group-A (intracameral) compared to 15.79% (n=15) in Group-B (subconjunctival) which was significantly different (p-value, 0.007). Conclusion: Intracameral injection is better than subjunctival injection of dexamethasone in the management of post-operative inflammation in children with congenital cataract.


Author(s):  
Harvinder Nagpal ◽  
Mandeep Kaur

Introduction: Previous equipments used to study cornea were mostly Placido based which could only analyse anterior surface of cornea, while Pentacam is based on elevation based imaging method that helps to study the curvature of cornea, its elevation and thickness profile more accurately. There are numerous studies published to study the thickness of cornea, this study outlines the importance of changes introduced in various corneal parameters with age which in itself is an important factor with possible positive correlation. Aim: To determine various corneal parameters and to interpret the variations in these with increasing age. Materials and Methods: This cross-sectional study included a cohort of 60 healthy patients attending Outpatient Department of Ophthalmology from July 2019 to February 2020. Two sets of values were determined, studied and compared between different age groups. First set of values included, keratometry values in the flat (K1) and steep (K2) and maximal keratometry values of the front surface (Kmax). Second set of values included, Anterior Elevations (AE), Posterior Elevations (PE), PE minus AE from Best Fit Sphere of 8 mm (BFS) and PE from the Best-fit Toric Ellipsoid (BFTE), apex thickness (CCT), pachymetry at the thinnest-point thickness (TCT),average corneal Pachymetry Progression Indices (PPI avg) and average Ambrosio’s Relational Thickness indices (ART avg). Based on age, three groups were created with 20 participants in each, Group A with age 18 to 25 years, Group B with age between 26 and 40 years and Group C with age more than 40 years. Scanning of all study subjects was done using Pentacam. Mann-Whitney U test and Spearman correlation test were used for the statistical analysis. Results: The average age was 21±2.42 years in group A, 30.9±4.3 years in group B and 42.45±1.65 years in group C. When AE, PE and PE-AE values were compared among three age groups, results were highly significant with p-value <0.00001. Thus, the elevation indices from BFS were found to be correlated with age. On comparison of PPI average between group A and B, group B and C values were statistically insignificant (p-values 0.51 and 0.19, respectively).Though in comparison between Group A and C, average corneal PPI avg was found to be of statistical significance (p-value=0.048). Average ART indices (ART avg) was found to produce highly statistically significant results among 3 groups (p-value <0.00001). Conclusion: The corneal parameters are significantly altered from their normative values with age. This study outlines that elevations indices and avg ART values are significantly altered with increasing age.


Author(s):  
Danilo Moyses Jorge ◽  
José Edísio da Silva Tavares Neto ◽  
Omero Benedicto Poli-Neto ◽  
Ingrid U. Scott ◽  
Rodrigo Jorge

Abstract Background The main purpose of this study is to compare the vitreous hemorrhage (VH) score reduction and visual acuity outcomes in patients with VH secondary to proliferative diabetic retinopathy (PDR) treated with intravitreal injections of bevacizumab (IVB) versus IVB and pars plana vitrectomy (IVB and PPV). Methods Patients with VH secondary to PDR were randomized into 2 groups: in Group A, patients were treated with a total of 3 IVB (1.5 mg/0.06 ml) at 8-week intervals; and in Group B, patients received a single IVB (1.5 mg/0.06 ml) and, 7 days later, underwent PPV. Patients received an ophthalmic evaluation that included best-corrected visual acuity (BCVA), indirect ophthalmoscopy, and mode B echography at weeks 8, 16 and 24. VH was classified according to the Diabetic Retinopathy Vitrectomy Study classification as grade 1, 2 or 3. Change in VH score was the primary outcome measure and change in BCVA was the secondary outcome. Results Seventy-three eyes of 66 patients were randomized and 70 eyes completed the 24-week follow-up visit. Mean VH score reduction (± SEM) of 0.4571 ± 0.0283 (p = 0.0014), 1.3429 ± 0.0393 (p < 0.0001) and 1.8286 ± 0.0438 (p < 0.001) was observed in Group A at 8, 16 and 24 weeks after treatment, respectively (Table 2; Fig. 2). In Group B, the reduction of VH score (± SEM) was 2.2571 ± 0.0720 (p = 0.0014), 2.2857 ± 0.0606 (p < 0.0001) and 2.2286 ± 0.0726 (p < 0.001) at 8, 16 and 24 weeks after treatment, respectively. Group comparison revealed a significantly greater reduction in mean VH score in Group B at 8 and 16 weeks after treatment (p < 0.0001). However, at 24 weeks this difference was no longer statistically significant (p = 0.1854). In Group A, mean (± SEM) BCVA showed an improvement of 0.00285 ± 0.0004 (p = 0.971), 0.5371 ± 0.0072 (p < 0.0001), 0.8143 ± 0.0001 (p < 0.0001) and 0.8543 ± 0.0008 (p < 0.0001) compared to baseline at 1, 8, 16 and 24 weeks after treatment, respectively. In Group B, mean (± SEM) BCVA showed an improvement of 0.3657 ± 0.0507 (p = 0.0002), 0.8857 ± 0.0385 (p < 0.0001), 0.9457 ± 0.0499 (p < 0.0001) and 0.9629 ± 0477 (p < 0.0001) compared to baseline at 1, 8, 16 and 24 weeks after treatment, respectively. No significant difference in BCVA improvement was observed between groups at 24 weeks after treatment. Conclusion PPV with preoperative IVB is associated with more rapid clearance of VH and improvement in BCVA than IVB injections alone. However, after 24 weeks of follow-up, the reduction in VH score and BCVA were similar between both treatment strategies. Trial Registration The project is registered in Plataforma Brasil with CAAE number 927354.7.0000.5440 and was approved by the Ethics Committee of the Clinics Hospital of Ribeirao Preto Medicine School of São Paulo University—Ribeirão Preto, São Paulo, Brazil (appreciation number 3.053.397 gave the approval).


1970 ◽  
Vol 1 (1) ◽  
pp. 20-24 ◽  
Author(s):  
A Sharma ◽  
H Das ◽  
S Adhikari ◽  
P Lavaju ◽  
BG Shrestha

Background: Trabeculectomy is the standard surgical procedure for management of glaucoma. Objective: To compare the outcome of triangular and rectangular scleral flaps in trabeculectomy. Materials and methods: This study was carried out in the Department of Ophthalmology, BPKIHS, Dharan, over a period of one year. A total of 22 patients undergoing trabeculectomy were randomized to undergo either trabeculectomy with triangular scleral flap (Group A= 11 eyes) or trabeculectomy with rectangular flap (Group B =11 eyes). Outcome measurement: The parameters studied were intraocular pressure (IOP), anterior chamber depth (ACD), bleb characteristics and surgical complications. Statistics: P value of <0.05 was considered significant. All calculations were executed using SPSS 11.0 software program. Results: The age ranged between 40 to 76 years with the mean of 56.5±9.25 years. The most common preoperative diagnosis was angle closure glaucoma. The postoperative percentage of IOP reduction (Group A=68.9%; Group B=66.51%) was statically significant in both the groups (p=0.001). Trabeculectomy was almost equally effective with complete surgical success of 91% in group A, and 82% in group B (p=0.534). Final bleb scores were almost similar in both the groups with 3.27 ± 1.5 in group A and 3.36±1.21 in group B (p=0.877). Hypotony with the IOP less than 6 mmHg was found in the first post-operative day in 2 patients in Group A and in 1 in Group B. All of them improved spontaneously within a week. Conclusion: Both triangular and rectangular scleral flaps in trabeculectomy are equally effective in terms of post surgical IOP control, bleb characteristics and complications. Keywords: Trabeculectomy; glaucoma; intra ocular pressure; scleral flap DOI: 10.3126/nepjoph.v1i1.3669 Nep J Oph 2009;1(1):20-24


2011 ◽  
Vol 18 (04) ◽  
pp. 715-721
Author(s):  
FAHEEM AHMAD ◽  
SYED ALI HAIDER

Introduction: The increasing popularity of phacoemulsificalion in restoring good visual acuity has also led to an increase in the incidence of its complications like nucleus drop during the procedure. Proper management of such patients not only reduces intravitreal lens fragments related complications but also significantly improves the visual acuity. Objectives: To evaluate the clinical features of the eye with retained Intravitreal lens fragments after the phacoemulsification surgery. We also aimed to investigate the incidence of cystoid macular edema, retinal detachment, suprachoridal hemorrhage and any other complication in patients after pars plana vitrectomy for retained intravitreal lens fragments. Setting: This study was carried out at the department of ophthalmology, Lahore General Hospital, Lahore. Period: The duration of study was one year 17-05-2004 to 28-04-2005. Study Design: Descriptive prospective. Material & Methods: The reported frequency of dislocated lens material at 0.3% is quiet low. Despite LGH being a referral center for retinal diseases, dropped nuclei and nuclear fragments constitute a very small fraction of the referred cases. Therefore the study was limited to 15 cases only so that it could be completed within specified period. Results: 15 eyes having retained lens matter after phacoemulsification surgery were included. Aphakia was present in 10(66.75%) patients. 5 (33.4%) patients were pseudophakic. Raised intraocular pressure was found in 11 (73.4%) patients, cornea! edema in 7 (46.7%), uveitis in 6 (40%) patients. Two (13.4%) patients had retinal detachment at presentation. The range of visual acuity way perception and projection of light to counting fingers in 9 eyes (60%), 2/60-6/60 in 5 eyes (33.4%). 6/24 in 1 (6.64%) eye preoperatively. After vitrectomy, range of visual acuity was 6/9 to 6/18 in 9 patients (60%) and 6/24-6/60 in 6 patients (40%). The comparison of pre-operative visual acuity and that of last follow-up showed p<0.01 (statistically highly significant). Intraocular pressure was raised in only 2 patients (13.3%). No patient developed retinal detachment. Cystoid macular edema was found in only 2 patients (13.4%).No patient developed significant intraocular inflammation after vitrectomy. Conclusions: Patients having retained intravitreal lens fragments presented with raised intraocular pressure, reduced visual acuity, uveitis and retinal detachment. In such patients combined pars plana vitrectomy and secondary intraocular lens implantation reduced the risk of postoperative complications including secondary glaucoma, uveilis and helped in restoration of useful visual acuity. 


2020 ◽  
pp. 112067212090203
Author(s):  
Alfonso Savastano ◽  
Chiara Lenzetti ◽  
Lucia Finocchio ◽  
Daniela Bacherini ◽  
Fabrizio Giansanti ◽  
...  

Purpose: To compare visual outcome and postoperative complications of combined 25-gauge pars plana vitrectomy and phacoemulsification with vitrectomy alone surgery in patients with epiretinal membrane and macular hole. Methods: A total of 110 eyes (73 eyes with epiretinal membrane and 37 eyes with macular hole) were enrolled in this prospective study. The eyes were divided into two groups: Group A included 55 eyes which underwent phacovitrectomy at the same time and Group B included 55 eyes which underwent vitrectomy alone. Follow-up visits were at 1, 3, and 6 months. Results: The best-corrected visual acuity correlation by analysis of variance measurement showed statistically non-significant differences between the two groups ( p = 0.32). The post hoc analysis from baseline, 1°, 2°, and 3° follow-ups was not statistically significant ( p > 0.05). The most common postoperative complication was cystoid macular edema that has been detected in 11 patients (10%) (seven eyes in Group A and four eyes in Group B): 2 patients (1.8%) developed a chronic macular edema. Intraocular hypertension occurred in five eyes (4.5%) (three in Group A and two in Group B). Four eyes (3.6%) underwent another surgical procedure for a persistent macular hole (two in Group A and two in Group B). The intraocular lens repositioning was performed one day after surgery in three eyes (2.7%) (Group A). The mean preoperative visual acuity was not different between the two groups ( p = 0.80). Conclusion: No significative differences between combined surgery and vitrectomy alone have been detected, in terms of postoperative complications and visual outcome.


2017 ◽  
Vol 2017 ◽  
pp. 1-7 ◽  
Author(s):  
Panagiotis Stavrakas ◽  
Paris Tranos ◽  
Angeliki Androu ◽  
Paraskevi Xanthopoulou ◽  
Dimitrios Tsoukanas ◽  
...  

Purpose. In this retrospective study, we evaluated the anatomical and functional outcomes of patients with rhegmatogenous retinal detachment primarily treated with pars plana vitrectomy in regard to the location of the breaks. Methods. 160 eyes were enrolled in this study, divided into two groups based on break location: the superior break group (115 eyes) and the inferior break group (45 eyes). The main endpoint of our study was the anatomical success at 3 months following surgery.Results. Primary retinal reattachment was achieved in 96.5% of patients in group A and in 93.3% in group B (no statistically significant difference, OR 1.98, 95% CI: 0.4, 7.7). Mean BCVA change and intraoperative complication rate were also not statistically significantly different between the two groups (p>0.05, OR: 1.0, 95% CI: 0.9, 1.01, resp.). Statistical analyses showed that macula status, age, and preoperative BCVA had a significant effect on mean BCVA change (p=0.0001,p=0.005, andp=0.001, resp.).Conclusion. This study supports that acceptable reattachment rates can be achieved using PPV for uncomplicated RRD irrespective of the breaks location and inferior breaks do not constitute an independent risk factor for worse anatomical or functional outcome.


Sign in / Sign up

Export Citation Format

Share Document