scholarly journals An Overview Knowledge and Usage of Herbal Medicines during The COVID-19 Pandemic by Students of Poltekkes Kemenkes Jakarta II

2021 ◽  
Vol 12 (2) ◽  
pp. 106-114
Author(s):  
Nanang Kurnia Achmadi ◽  
Yayan Setiawan ◽  
Aprilia Ayu Purwati
Keyword(s):  
Herbal Medicine ◽  
Global Health ◽  
Health Problem ◽  
Sampling Method ◽  
Univariate Analysis ◽  
Herbal Medicines ◽  
Herbal Remedies ◽  
Primary Data ◽  
Knowledge Usage ◽  
Global Health Problem

COVID-19 has now become a global health problem. In Indonesia, there are 828.026 confirmed cases as of January 10, 2021.(1) To deal with this current situation, prevention efforts are needed. One of them increases endurance by using herbal remedies. In addition to having been used for generations, several studies have shown that herbal medicines have the potential to increase endurance.The purpose of this study was to describe the knowledge and usage of herbal medicines during the COVID-19 pandemic.This study using the purposive sampling method with one hundred respondents. Data were collected based on primary data using a google form questionnaire with univariate analysis. On Preliminary results are Most of respondents had pretty good knowledge in forty eight point eight percent, and jamu on sixty nine point five percent as the herbal medicine of choice, when pharmacies to get herbal medicines. Moreover, the implications are the knowledge of using herbal medicine during the COVID-19 pandemic is good and Jamu is the most used herbal medicine based of the types. This research will be continued with more samples to better represent the conclusions.   Keywords: Knowledge, Usage, Herbal Medicines

scholarly journals Osmium–arene complexes with high potency towards Mycobacterium tuberculosis

Metallomics ◽  
2021 ◽  
Vol 13 (4) ◽  
Author(s):  
James P C Coverdale ◽  
Collette S Guy ◽  
Hannah E Bridgewater ◽  
Russell J Needham ◽  
Elizabeth Fullam ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
Global Health ◽  
Mechanism Of Action ◽  
Health Problem ◽  
Normal Lung ◽  
Lung Cells ◽  
Redox Mechanism ◽  
Human Lung Cells ◽  
Half Sandwich ◽  
Global Health Problem

Abstract The treatment of tuberculosis (TB) poses a major challenge as frontline therapeutic agents become increasingly ineffective with the emergence and spread of drug-resistant strains of Mycobacterium tuberculosis (Mtb). To combat this global health problem, new antitubercular agents with novel modes of action are needed. We have screened a close family of 17 organometallic half-sandwich Os(II) complexes [(arene)Os(phenyl-azo/imino-pyridine)(Cl/I)]+Y– containing various arenes (p-cymene, biphenyl, or terphenyl), and NMe2, F, Cl, or Br phenyl or pyridyl substituents, for activity towards Mtb in comparison with normal human lung cells (MRC5). In general, complexes with a monodentate iodido ligand were more potent than chlorido complexes, and the five most potent iodido complexes (MIC 1.25–2.5 µM) have an electron-donating Me2N or OH substituent on the phenyl ring. As expected, the counter anion Y (PF6–, Cl–, I–) had little effect on the activity. The pattern of potency of the complexes towards Mtb is similar to that towards human cells, perhaps because in both cases intracellular thiols are likely to be involved in their activation and their redox mechanism of action. The most active complex against Mtb is the p-cymene Os(II) NMe2-phenyl-azopyridine iodido complex (2), a relatively inert complex that also exhibits potent activity towards cancer cells. The uptake of Os from complex 2 by Mtb is rapid and peaks after 6 h, with temperature-dependence studies suggesting a major role for active transport. Significance to Metallomics Antimicrobial resistance is a global health problem. New advances are urgently needed in the discovery of new antibiotics with novel mechanisms of action. Half-sandwich organometallic complexes offer a versatile platform for drug design. We show that with an appropriate choice of the arene, an N,N-chelated ligand, and monodentate ligand, half-sandwich organo–osmium(II) complexes can exhibit potent activity towards Mycobacterium tuberculosis (Mtb), the leading cause of death from a single infectious agent. The patterns of activity of the 17 azo- and imino-pyridine complexes studied here towards Mtb and normal lung cells suggest a common redox mechanism of action involving intracellular thiols.

Investigation of therapeutic potential of three endemic Cirsium species for global health problem obesity

2021 ◽  
Vol 141 ◽  
pp. 243-254
Author(s):  
Sila Ozlem Sener ◽  
Ufuk Ozgen ◽  
Seyda Kanbolat ◽  
Nuriye Korkmaz ◽  
Merve Badem ◽  
...  
Keyword(s):  
Global Health ◽  
Health Problem ◽  
Therapeutic Potential ◽  
Global Health Problem

Herbal Remedies and Children: Do They Work? Are They Harmful?

PEDIATRICS ◽  
2003 ◽  
Vol 112 (Supplement_1) ◽  
pp. 240-246 ◽  
Author(s):  
Alan D. Woolf
Keyword(s):  
Primary Care ◽  
Herbal Medicine ◽  
Herbal Medicines ◽  
Good Health ◽  
Herbal Remedies ◽  
Herbal Products ◽  
Safety And Efficacy ◽  
Primary Care Clinicians

More parents are considering the use of herbal remedies to maintain their children’s good health and to treat their illnesses. They look to pediatricians and other primary care clinicians for advice concerning the safety and efficacy of herbal products for children. This article reviews principles for the clinician to keep in mind while investigating the literature on herbal medicine and addressing the use of herbal medicines with parents.

The potential impact of the use of homeopathic and herbal remedies on monitoring the safety of prescription products

2005 ◽  
Vol 24 (5) ◽  
pp. 219-233 ◽  
Author(s):  
K N Woodward
Keyword(s):  
Herbal Medicine ◽  
Drug Interactions ◽  
Adverse Reactions ◽  
Conventional Medicine ◽  
Herbal Medicines ◽  
Adverse Event Reporting ◽  
Herbal Remedies ◽  
Extensive Literature ◽  
Conventional Drug ◽  
Potential Impact

The purpose of this paper is to explore the possibility that adverse reactions and drug interactions arising from the use of homeopathic and herbal medicines could lead to confusion when adverse reactions to conventional medicines are reported. An extensive literature review was conducted on the occurrence of adverse reactions and drug interactions following the use of homeopathic or herbal remedies, and the potential for these to confound adverse event reporting to conventional medicines considered. The survey demonstrates the potential for herbal remedies and homeopathic products, to produce adverse drug reactions or drug interactions, and shows the scope for potential for confusion with those arising from conventional medicines. There is a need for greater awareness that adverse reactions apparently due to a conventional medicine, might in reality be due to a herbal medicine or a drug interaction between a herbal medicine and a conventional drug, particularly when a health professional is unaware of the extent of a patient's selfmedication with alternative therapies.

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