scholarly journals BIOINFORMATICS APPROACHES TO UNDERSTAND GENE LOOPING IN THE HUMAN GENOME

Author(s):  
Sudheer Menon

This paper reviews up to date Bioinformatics Approaches to Understand Gene Looping in the Human Genome. Bioinformatics is used to study the sequences of biological molecules. It generally points out to genes, DNA, RNA, or protein, and is especially functional in analogizing genes and other protein sequences. You can believe in bioinformatics. Basically, the linguistics Bioinformatics uses computer programs for various applications, involving deliberate gene and protein functions. The beginning of the human genome project in 1990 and was completed in 2003. The Human Genome Project gave a prime improvement for the progress of bioinformatics. The (HGP) was organized by the National Institutes of Health and the U.S. Department of Energy. Without the interpretation given via bioinformatics, the information obtained from the HGP is not very functional. This page describes HGP bioinformatics research. Informatics is the formation, exploration, and function of databases. Main aim was to find the total set of human genes and make them available for more biological study and discover the total sequence of DNA bases in the human genome. A total and the correct sequence of the 3 billion DNA base pairs create the human genome and search all approximate 20,000 to 25,000 human genes. The genomes sequence of organisms that are main to medical research. To begin new tools to apply and inspect the data and to assemble this information broadly obtainable. DNA sequencing manufactures a sequence that is particularly a hundred bases long. Gene sequences manufacture thousands of bases. To study genes, small intersecting sequences set up long DNA sequences. Loops can clump associated genes into separate transcriptional axis chromatin from neighboring domains. Gene loops in yeast juxtapose promoter-terminator regions. Here we outline gene loops’ finding, the looping need proteins, and transcription by RNA polymerase II is by gen looping

1993 ◽  
Vol 12 (2) ◽  
pp. 273-275 ◽  
Author(s):  
Elinor J. Langfelder ◽  
Eric T. Juengst

The program on the Ethical, Legal, and Social Implications (ELSI) of human genome research is a branch of the National Center for Human Genome Research (NCHGR) at the National Institutes of Health (NIH). The NCHGR is responsible, in conjunction with the Office of Health and Environment at the Department of Energy (DOE), for administration and coordination of the U.S. component of the Human Genome Project.


2019 ◽  
Vol 63 (4) ◽  
pp. 457-468 ◽  
Author(s):  
Mark A. J. Roberts

Abstract DNA present in all our cells acts as a template by which cells are built. The human genome project, reading the code of the DNA within our cells, completed in 2003, is undoubtedly one of the great achievements of modern bioscience. Our ability to achieve this and to further understand and manipulate DNA has been tightly linked to our understanding of the bacterial and viral world. Outside of the science, the ability to understand and manipulate this code has far-reaching implications for society. In this article, we explore some of the basic techniques that enable us to read, copy and manipulate DNA sequences alongside a brief consideration of some of the implications for society.


1996 ◽  
Vol 13 (2) ◽  
pp. 63-95 ◽  
Author(s):  
Eric T. Juengst

On October 1, 1988, thirty-five years after co-discovering the structure of the DNA molecule, Dr. James Watson launched an unprecedented experiment in American science policy. In response to a reporter's question at a press conference, he unilaterally set aside 3 to 5 percent of the budget of the newly launched Human Genome Project to support studies of the ethical, legal, and social implications of new advances in human genetics. The Human Genome Project (HGP), by providing geneticists with the molecular maps of the human chromosomes that they use to identify specific human genes, will speed the proliferation of a class of DNA-based diagnostic and risk-assessment tests that already create professional ethical and health-policy challenges for clinicians. “The problems are with us now, independent of the genome program, but they will be associated with it,” Watson said. “We should devote real money to discussing these issues.” By 1994, the “ELSI program” (short for “Ethical, Legal, and Social Implications”) had spent almost $20 million in pursuit of its mission, and gained both praise and criticism for its accomplishments.


Biomolecules ◽  
2021 ◽  
Vol 11 (1) ◽  
pp. 90
Author(s):  
Ryuji Hamamoto

The Human Genome Project, completed in 2003 by an international consortium, is considered one of the most important achievements for mankind in the 21st century [...]


1993 ◽  
Vol 36 (3) ◽  
pp. 466-475 ◽  
Author(s):  
BELINDA J. F. ROSSITER ◽  
C THOMAS CASKEY

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