Cervical lymph node metastasis revealing a prostate adenocarcinoma: About two observations and Review of the Literature

Prostatic adenocarcinoma is the most common cancer in men, and is the 3rd leading cause of death in men worldwide. This slow-growing, hormone-sensitive cancer occurs after the age of 50 years. Cervical lymph node metastases of prostate adenocarcinoma are rare. We report two anatomical observations over a ten-year period of activity. The two men were aged 80 and 72 years, respectively, and both presented with multiple cervical adenopathies of particular topography above the clavicle, associated with urinary signs such as dysuria, pollakiuria and incontinence. Microscopic examination coupled with immunohistochemistry (anti-PSA antibodies) of the excised biopsy of these lymph nodes contributed to the diagnosis of certainty. Keywords: Adenocarcinoma; Prostate; Metastasis; Node; Neck; Immunohistochemistry