scholarly journals Results of surgical treatment of the oral and oropharyngeal cancer

Author(s):  
Natalya M. Trizna ◽  
Zhanna V. Kaliadich

Materials and methods: The results of surgical treatment in 30 patients with oral and oropharyngeal cancer were studied. Postoperative surgical complications were analyzed according to the Clavien-Dindo classification, the causes of postoperative complications after reconstructive operations. Results: Postoperative complications developed in 20.0% of cases and were represented by dehiscence of the wound edges, bleeding, and in the long-term period by the formation of a pharyngostomy, osteradionecrosis with a pathological fracture of the jaw. The resulting post-resection defects are inevitably accompanied by severe functional impairments: impaired opening of the mouth was noted in 36.7% of patients, impaired swallowing - in 3.3%, speech impairments - in all patients. The acoustic characteristics of speech were lower than those of a healthy person.

Author(s):  
N Bobrova ◽  
N Trofimova

The aim of the work was to analyze the long-term results of using a temporary “liquid” implant in the surgery of congenital glaucoma in children. The basis of the developed method of filtrative antiglaucomatous surgery (Patent of Ukraine No. 45099 of 2009) – viscosinusotrabeculotomy – has been set the task of reducing the risk of developing intra- and postoperative complications, reducing the scarring rate and maintaining the newly created ways of the intraocular fluid outflow, which in general will increase the effectiveness of surgical treatment of congenital glaucoma in children. 54 children (91 eyes) with simple congenital glaucoma at the age of 1 to 36 months were operated on average (8.7 ± 8.2) months. The persistent and long-lasting hypotensive effect achieved due to viscosinusotrabeculotomy in children with developed and far-advanced stages of congenital glaucoma stops the processes of stretching of the membranes of the eye and stabilizes their size, which in general allows preserving and visual functions improving, in infancy – creating conditions for their formation.


2018 ◽  
Vol 25 (13) ◽  
pp. 3874-3882 ◽  
Author(s):  
Linda B. M. Weerink ◽  
Christina M. Gant ◽  
Barbara L. van Leeuwen ◽  
Geertruida H. de Bock ◽  
Ewout A. Kouwenhoven ◽  
...  

Head & Neck ◽  
2005 ◽  
Vol 27 (9) ◽  
pp. 785-793 ◽  
Author(s):  
Pepijn A. Borggreven ◽  
Irma Verdonck-de Leeuw ◽  
Johannes A. Langendijk ◽  
Patricia Doornaert ◽  
Marike N. Koster ◽  
...  

2019 ◽  
Vol 12 (3) ◽  
pp. 1055
Author(s):  
Gleb I. Mikusev ◽  
Rustem F. Baikeev ◽  
Ruslan O. Magomedov ◽  
Ivan E. Mikusev ◽  
Timur S. Mishakin

Oral Oncology ◽  
2007 ◽  
Vol 43 (10) ◽  
pp. 1034-1042 ◽  
Author(s):  
Pepijn A. Borggreven ◽  
Neil K. Aaronson ◽  
Irma M. Verdonck-de Leeuw ◽  
Martin J. Muller ◽  
Milou L.C.H. Heiligers ◽  
...  

2020 ◽  
Vol 10 (2) ◽  
pp. 33-41
Author(s):  
B. B. Akhmedov ◽  
P. V. Kononets ◽  
M. Yu. Fedyanin ◽  
Z. Z. Mamedli ◽  
S. S. Gordeev ◽  
...  

Objective: to evaluate short-term and long-term outcomes of surgical treatment for colorectal cancer metastases to the lungs and to analyze factors affecting the efficacy of surgery. Materials and methods. This study included 211 patients with colorectal cancer metastases to the lungs treated between 1994 and 2014. We enrolled patients with resectable or conventionally resectable metastases (according to chest computed tomography evaluated by a thoracic surgeon); the exclusion criteria were as follows: multiple primary tumors and age more than 85 years. We assessed the type of surgeries, frequency of R0 resections, incidence of postoperative complications, overall survival, and progression-free survival. Results. One hundred and sixty-two patients out of 211 (76.8 %) have undergone atypical lung resection. Forty-nine patients (23.2 %) have undergone pneumonectomy, bilobectomy, or lobectomy. The majority of patients (96.2 %) have had R0 resection, whereas 2.9 % of study participants have had R1 or R2 resections. One patient has undergone a trial surgery. Clinically significant postoperative complications were observed in 4 (2 %) patients; postoperative mortality was 0.5 % (1 case). The five-year overall survival rate was 52.7 %; the 5-year progression-free survival rate was 45.8 %. Development of metastases within 24 months after primary surgery was found to be a significant factor negatively affecting overall survival (hazard ratio 0.347; 95 % confidence interval 0.227–0.53; р <0.0001). Conclusions. Surgical treatment is currently the only truly effective treatment, which can improve long-term survival of patients with colorectal cancer metastases to the lungs; the best treatment results are achieved in patients with a relapse-free interval of more than 24 months. 


2021 ◽  
Vol 59 (1) ◽  
pp. 31-35
Author(s):  
Natalia Trizna ◽  
Zhanna Kaliadich ◽  
Alena Zhaleiko ◽  
Alesya Evmenenko

Relevance: The study of the patients’ quality of life is an important part of a comprehensive analysis of new diagnostic, treatment, and prevention methods. It can serve as an additional criterion for selecting individual therapy or rehabilitation, examining the ability to work, and identifying psychological problems. Purpose: To show the potential of evaluating the outcome of surgical treatment of oral and oropharyngeal cancer with plastic replacement of the post-resection defect by the study of dynamics of patient’s quality of life (on a clinical case) Results: The anticancer treatment effects were reflected in the physical functioning score according to the EORTC QLQ-C30 questionnaire (reduced to 80 points) and some symptomatic scores according to the EORTC QLQ-C30 and EORTC QLQ-H & N35 questionnaires. Medical rehabilitation measures improved physical functioning scores according to the EORTC QLQ-C30 questionnaire (increase to 93.3 points) and symptomatic scores according to the EORTC QLQ-H & N35 questionnaire related to nutrition. At that, the patient has stopped having difficulty eating in public places; his body weight increased. The absence of pain and refusal to take analgesics also testified to successful treatment and improved quality of life. Conclusion: A subjective assessment of the various quality of life aspects in a particular patient provides valuable information about the individual response to the conducted treatment.


Sign in / Sign up

Export Citation Format

Share Document