Relationship of pre-operative serum brain natriuretic peptide with risk of acute kidney injury after cardiac surgery

2015 ◽  
Vol 36 (5) ◽  
pp. 560
Author(s):  
Li-jun SUN ◽  
Cheng XUE ◽  
Hai-peng SUN ◽  
Cheng-gang XU ◽  
Bai-ling LI ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Kidney Injury ◽  
Relationship Of

scholarly journals Preoperative Serum Brain Natriuretic Peptide and Risk of Acute Kidney Injury After Cardiac Surgery

Circulation ◽  
2012 ◽  
Vol 125 (11) ◽  
pp. 1347-1355 ◽  
Author(s):  
Uptal D. Patel ◽  
Amit X. Garg ◽  
Harlan M. Krumholz ◽  
Michael G. Shlipak ◽  
Steven G. Coca ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Kidney Injury ◽  
Preoperative Serum

Prevention of acute kidney injury

2018 ◽  
Author(s):  
Norbert Lameire
Keyword(s):  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Growth Factor ◽  
Atrial Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Potential Role ◽  
Kidney Injury ◽  
Pharmacological Interventions ◽  
Selection Of

This chapter summarizes the pharmacological interventions that can be used in the prevention of acute kidney injury (AKI). These following interventions are discussed: the use and selection of vasopressors; the administration of loop diuretics and mannitol; vasodilating drugs including dopamine, atrial natriuretic peptide, nesiritide, fenoldopam, and adenosine antagonists. The role of N-acetylcysteine in the prevention of contrast-induced AKI and cardiac surgery is discussed. The chapter concludes with a summary of the potential role of insulin-like growth factor and erythropoietin in the prevention of AKI.

scholarly journals Predictors of Post-Operative Acute Kidney Injury in relation with N-Terminal Pro-B-Type Natriuretic Peptide Level among Patients Undergoing Mitral Valve Replacement

2021 ◽  
Vol 8 (2) ◽  
pp. 85-89
Author(s):  
Md Tanvir Hossain ◽  
Asraful Hoque ◽  
Tasmin Rubayath ◽  
Romena Rahman ◽  
Abu Shadat Mohammad Saem Khan ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Cardiac Surgery ◽  
Mitral Valve ◽  
Valve Replacement ◽  
Natriuretic Peptide ◽  
Mitral Valve Replacement ◽  
Kidney Injury ◽  
Natriuretic Peptide Level ◽  
Peptide Level ◽  
Operative Variable

Background: The N-terminal Pro-B-type natriuretic peptide (NT-proBNP) level can be utilized as post-operative prediction models suring cardiac surgery. Objective: The objective was to find out the predictors of post-operative acute kidney injury in relation with N-Terminal Pro-B-Type natriuretic peptide level among mitral valve replacement patients. Methodology: This cross-sectional study was conducted in the Department of Cardiac Surgery at National Institute of Cardiovascular Diseases, Dhaka, Bangladesh from January 2018 to December 2019. Patients with the age of more than or equal to 18 years with both sexes who were underwent mitral valve replacement were selected as study population. Patients were divided into two groups based on pre-operative NT-proBNP level. Post-operatively patients were observed on the basis of post-operative serum creatinine. Results: A total number of 100 patients were recruited for this study of which 50 cases were in group A and the rest of 50 cases were in the group B. Elevated NT-proBNP was the most powerful and independent pre-operative variable in predicting post-operative AKI development (OR 0.999, 95% CI 0.998-1.00) Conclusion: In conclusion elevated NT-proBNP is the most powerful and independent pre-operative variable in predicting post-operative acute kidney injury. Journal of Current and Advance Medical Research, July 2021;8(2):85-89

scholarly journals Serum Brain Natriuretic Peptide and Risk of Acute Kidney Injury After Cardiac Operations in Children

2014 ◽  
Vol 97 (6) ◽  
pp. 2142-2147 ◽  
Author(s):  
Christoph P. Hornik ◽  
Catherine D. Krawczeski ◽  
Michael Zappitelli ◽  
Kwangik Hong ◽  
Heather Thiessen-Philbrook ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Kidney Injury ◽  
Cardiac Operations

scholarly journals Value of N-terminal pro brain natriuretic peptide in predicting acute kidney injury in patients with acute decompensated chronic heart failure

2017 ◽  
Vol 89 (3) ◽  
pp. 78-84 ◽  
Author(s):  
M V Menzorov ◽  
A M Shutov ◽  
V I Midlenko ◽  
N V Larionova ◽  
I V Morozova ◽  
...  
Keyword(s):  
Heart Failure ◽  
Acute Kidney Injury ◽  
Chronic Heart Failure ◽  
Brain Natriuretic Peptide ◽  
Natriuretic Peptide ◽  
Considerable Increase ◽  
Kidney Injury ◽  
Mortality Rates ◽  
High Level ◽  
Rule Out

Aim. To investigate the prognostic value of serum N-terminal pro-brain natriuretic peptide (NT-proBNP) in the development of acute kidney injury (AKI) in patients with acute decompensated chronic heart failure (ADCHF). Subjects and methods. Eighty-three patients (55 (66%) men and 28 (34%) women; mean age, 65±11 years) with ADCHF were examined. AKI was diagnosed and classified according to the 2012 Kidney Disease Improving Global Outcomes Clinical Practice guidelines. To rule out contrast-induced AKI, the investigation enrolled only patients in whom radiopague agents had not been injected 7 days before and during hospitalization. Enzyme immunoassay was used to determine serum NT-proBNP concentrations in all the patients upon hospital admission. Results. AKI was diagnosed in 18 (22%) patients, 13 (16%) had Stage I, 4 (5%) had Stage II, and 1 (1%) had Stage III. The serum concentration of NT-proBNP was significantly higher in patients with AKI than that in the other patients [1512.1 (981.0; 2246.2) and 861.8 (499.0; 1383.6) pg/ml (p=0.008). The rise in NT-proBNP concentrations of more than 942 pg/ml was established to be associated with a considerable increase in the risk of AKI (relative risk (RR) was 4.3; 95% confidence interval (CI), 1.27—14.90; p=0.02). RОС analysis indicated that a NT-proBNP level of >942 pg/ml allows prediction of AKI with a sensitivity of 78% (52; 94) and a specificity of 55% (44; 69) (AUC=0.70; p=0.006). Four (5%) patients died in hospital. NT-proBNP levels in all the dead were greater than 942 pg/ml. Two of the 4 deceased patients had AKI. Conclusion. A high level of NT-proBNP in a patient with ADCHF during hospitalization can serve as a biomarker for high risk of AKI and for high mortality rates.

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