Multifocal Osteonecrosis Glucocorticoid Induced

2017 ◽  
Vol 68 (1) ◽  
pp. 200-202
Author(s):  
Alexandru Patrascu ◽  
Liliana Savin ◽  
Olivera Lupescu ◽  
Dan Mihailescu ◽  
Dana Nicoleta Mihai ◽  
...  

The present study describes a 29 years old patient diagnosed with aseptic osteonecrosis with multiple localization occurred after a corticoid treatment for chronic toxic hepatitis. The clinical and para-clinical examinations determined the diagnosis of Wilson disease and avascular necrosis with multiple localizations. The evolution of the disease was favourable following the surgical treatment consisting of bilateral total hip arthroplasty with cementless prosthesis, hemi-arthroplasty of the left shoulder with cementless prosthesis, orthotopic hepatic transplantation with an entire liver from donor in cerebral death and immunosuppressive, anticoagulant, antiretroviral and gastro-protective treatment. There is an increase of the number of patients undergoing a glucocorticoids treatment for several months, years or lifelong periods. This type of treatment increases the risk of osteonecrosis depending on the dosage and the duration of the treatment.

2020 ◽  
Vol 73 (3) ◽  
pp. 517-520
Author(s):  
Anastasia I. Furdychko ◽  
Marta P. Ilchyshyn ◽  
Irena R. Fedun ◽  
Adriana Ya. Barylyak ◽  
Oksana M. Slaba ◽  
...  

The aim: To study the effect of drug addiction and smoking on the status of periodontal tissues in patients with hepatobiliary pathology. Materials and methods: 58 smokers, 63 drug addicts with hepatobiliary pathology were examined and 92 persons of comparison group (with inflammatory periodontal diseases affected by hepatobiliary pathology, without addiction). Examination of patients included determination of iodine number by Svrakov, S-L and Stallard hygiene indices, PMA index and index PBI. Results: The results of examination of smokers are worse in patients with cirrhosis than in patients with chronic toxic hepatitis and non-alcoholic steatohepatitis and also the results of these two groups was significantly worse than that of the comparison group (iodine number by Svrakov – 1,4 times and 1,3 times higher, PMA index – 1,7 times and 1,4 times worse, in accordance). The results of the study showed that drug addicts patients are worse values in patients with cirrhosis than in patients with chronic toxic hepatitis and non-alcoholic steatohepatitis and also the results of these two groups was significantly worse than that of the comparison group (iodine number by Svrakov – 1,5 times and 1,4 times higher, PMA index – 1,7 times and 1,5 times worse, in accordance). Conclusions: Presence of hepatobiliary pathology in smokers and drug addicts increases the risk of periodontal diseases.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Kalilou Diallo ◽  
Bruce Shinga Wembulua ◽  
Mohamadou Aidara ◽  
Armel Alleyo ◽  
Noel Magloire Manga

Abstract Background Human immunodeficiency virus-infected patients are 100 times more likely to develop aseptic osteonecrosis compared with the general population. While 90% of cases concern the femoral head, the involvement of humeral bone remains rare. Case presentation We report a case of aseptic osteonecrosis of the left humeral head complicating antiretroviral therapy in a female, 46-year-old, Bissau-Guinean human immunodeficiency virus-infected patient received in a context of progressive pain in the left shoulder followed by limitation of articular movements. Standard x-ray of the shoulder allowed us to make the diagnosis by showing a typical image of osteonecrosis. The treatment was medical combined with physiotherapy. Conclusions Aseptic osteonecrosis should be systematically looked for in human immunodeficiency virus patients on antiretroviral treatment. In addition to femoral head aseptic necrosis, the involvement of the humeral bone should also be considered.


1986 ◽  
Vol 20 (5) ◽  
pp. 293-296
Author(s):  
I. O. Ubasheev ◽  
K. S. Lonshakova ◽  
�. I. Matkhanov ◽  
O. D. Tsyrenzhanova

1975 ◽  
Vol 79 (1) ◽  
pp. 20-22
Author(s):  
T. A. Korolenko ◽  
V. G. Titova ◽  
S. G. Dobrovol'skaya ◽  
G. S. Yakobson

2008 ◽  
Vol 146 (5) ◽  
pp. 566-568 ◽  
Author(s):  
Ju. I. Borodin ◽  
Ju. V. Bashkirova ◽  
M. S. Lyubarsky ◽  
M. A. Kolpakov

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