The Utility of Visceral Adiposity Index in Prediction of Metabolic Syndrome and Hypercholesterolemia

Metabolic syndrome (MS) is defined as a complex entity that involves the accumulation of cardiovascular and metabolic risk factors represented by: abdominal obesity, insulin resistance, hypertension, dyslipidemia [1]. The presence of MS correlates with the risk of cardiovascular disease in people without diabetes mellitus (DM), as well as those with type 2 DM [2-8].Visceral adipose tissue is an active metabolic organ and abdominal obesity is an independent risk factor for metabolic disorder present in MS [9,10,11], associated with the development of cardiovascular disease and type 2 diabetes in children, adolescents and adults [12-15]. Our findings have shown an association of visceral adiposity index (VAI) with MS in both men and women with prediabetes and diabetes, these findings allow us to conclude that VAI is a simple but effective indicator for estimating the presence of MS among adults.

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Lipid Indices vs Anthropometric Indices in Metabolic Syndrome and Type 2 Diabetes Mellitus

Annals of Pathology and Laboratory Medicine ◽

10.21276/apalm.3060 ◽

2021 ◽

Vol 8 (6) ◽

pp. A152-157

Author(s):

Asha Augusthy ◽

Suchanda Sahu ◽

Ashok Kumar Jeppu

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Metabolic Syndrome ◽

Type 2 Diabetes Mellitus ◽

Visceral Adiposity ◽

Accumulation Factor ◽

Visceral Adiposity Index ◽

Anthropometric Indices ◽

Adiposity Index

Background: Diabetes mellitus is a metabolic disease known by chronic hyperglycemia which results from defective insulin action and secretion. Metabolic Syndrome consists of a constellation of metabolic abnormalities that confer increased risk of diabetes mellitus. The aim of our study is to find out whether non-invasive, clinically measurable surrogates could be useful in identifying body fat distribution and help predict metabolic syndrome and diabetes risk and to compare the performance of anthropometric indices with lipid indices in identifying metabolic syndrome and diabetes. Methods: 50 individuals with metabolic syndrome ,50 individuals with type 2 diabetes mellitus and 50 controls were selected by purposive sampling technique. For cases and controls history was taken, physical examination was done .Fasting blood sugar, Serum High density lipoprotein and Serum Triglyceride levels were estimated. Body mass index, a body shape index, visceral adiposity index, lipid accumulation factor was calculated. Results: The mean values visceral adiposity index, lipid accumulation factor were significantly increased (p<0.001) in cases compared to controls. Conclusion: Our study concluded that lipid indices visceral adiposity index, lipid accumulation factor is better than anthropometric indices like body mass index, a body shape index in predicting metabolic syndrome and type 2 diabetes mellitus. Anthropometric indices when used should be correlated with metabolic variables and clinical symptoms.

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Lipid Accumulation Product (LAP) and Visceral Adiposity Index (VAI) a Simple and Clinically Useful Surrogate Marker for Metabolic Syndrome and Cardiovascular Disease Predictor in Non-diabetic Venezuelan Adults

Journal of Pharma & Pharmaceutical Sciences ◽

10.24218/vjpps.2017.20 ◽

2017 ◽

Vol 2 (1) ◽

pp. 1-8 ◽

Cited By ~ 1

Author(s):

Manuel Velasco

Keyword(s):

Cardiovascular Disease ◽

Metabolic Syndrome ◽

Lipid Accumulation ◽

Surrogate Marker ◽

Visceral Adiposity ◽

Visceral Adiposity Index ◽

Lipid Accumulation Product ◽

Adiposity Index

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Visceral adiposity index among young girls with PCOS and its association with phenotypes and metabolic risk

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20180164 ◽

2018 ◽

Vol 7 (2) ◽

pp. 513

Author(s):

Beena Joshi ◽

Tejal Lakhan ◽

Srabani Mukherji ◽

Anushree Patil ◽

Sayeed Unisa

Keyword(s):

Metabolic Syndrome ◽

Surrogate Marker ◽

Secondary Data ◽

Small Sample ◽

Visceral Adiposity ◽

Visceral Adiposity Index ◽

Adiposity Index ◽

Unit Increase ◽

Adipose Dysfunction ◽

Visceral Adipose

Background: Polycystic Ovarian Syndrome (PCOS) is a growing endocrine-metabolic disease in India. Visceral Adiposity Index (VAI) is a surrogate marker of visceral adipose dysfunction and can be used as a useful predictor of unhealthy PCOS phenotypes in low resource settings. No cut-off has been assessed among Indian population.Methods: Secondary data from 106 diagnosed girls with PCOS and 121 controls was analysed to estimate (i) VAI and BMI among different phenotypes (ii) risk of metabolic disorders using VAI among different phenotypes of PCOS and (iii) compare the overall diagnostic performance (for metabolic syndrome) of VAI, BMI and waist circumference.Results: Majority of the girls in the sample considered for analysis were lean PCOS (61%). Mean VAI among PCOS (3.02) was significantly higher than normal controls (2.81). Classic and Mild Phenotypes had high VAI. A unit increase in VAI score was found associated with 5.23 times higher risk of metabolic syndrome (AOR: 5.23, 95% CI: 2.261-12.086). A higher VAI with cut off value of 2.73 could predict risk of metabolic syndrome among PCOS cases, unlike the cutoff among Caucassian population of 1.67. The cut-off for the non- obese group was even higher i.e. 2.81.Conclusions: Given that Indians are genetically more prone to have excess visceral fat the cut-offs for measuring adiposity also needs to be re-defined. The findings of this small sample throws light on the prevalence of visceral adiposity among lean girls with PCOS emphasizing the need to also screen them for metabolic syndrome, educate them about these complications and motivate them to practice healthy lifestyles.

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