Current preventive treatment for recurrence after curative hepatectomy for liver metastases of colorectal carcinoma: A literature review of randomized control trials

Background The use of prophylactic systemic antibiotics with nasal packing has been a controversial topic. There are few evidence-based studies to determine the need for prophylactic systemic antibiotics. We performed a systematic literature review to determine the role of prophylactic systemic antibiotics with nasal packing in the prevention of toxic shock syndrome and local nasal infections. Objective The purpose of this study was to perform a systematic literature review to determine the role of prophylactic systemic antibiotics with nasal packing in the prevention of toxic shock syndrome and local nasal infections. Methods A search for studies that reviewed the efficacy of prophylactic systemic antibiotics in the prevention of toxic shock or nasal infections and/or sinusitis for patients with nasal packing for epistaxis and postoperative septoplasties was performed. This was conducted in a number of medical literature data bases by following the methods of the 2009 Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Only English publications and human studies that were randomized control trials, quasi-randomized control trials, controlled clinical trials, retrospective studies, and case series were included. Results Six studies, with a total of 990 patients, met the inclusion criteria for the review and were included. Primary outcomes were signs and symptoms of nasal or sinus infections in patients who underwent nasal packing for epistaxis or septoplasty. There were no reports of toxic shock syndrome in any patients, and there was no statistical difference in purulent drainage in patients who had septoplasty (9.9 versus 11.2%) treated with or without antibiotics. Conclusion There is a paucity of literature that reviewed the need for prophylactic systemic antibiotics with nasal packing. The available literature does not show a significant benefit to the use of antibiotics with nasal packing, but the studies were underpowered to detect such a difference. One must consider the associated risks of prophylactic antibiotics to the patient as well when deciding to prescribe prophylactic antibiotics.

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Preventive treatments for recurrence after curative resection of hepatocellular carcinoma - A literature review of randomized control trials

World Journal of Gastroenterology ◽

10.3748/wjg.v9.i4.635 ◽

2003 ◽

Vol 9 (4) ◽

pp. 635 ◽

Cited By ~ 48

Author(s):

Hui-Chuan Sun

Keyword(s):

Hepatocellular Carcinoma ◽

Literature Review ◽

Curative Resection ◽

Randomized Control Trials ◽

Randomized Control

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Whole Grain Consumption and Inflammatory Markers: A Systematic Literature Review of Randomized Control Trials

Nutrients ◽

10.3390/nu14020374 ◽

2022 ◽

Vol 14 (2) ◽

pp. 374

Author(s):

Genevieve Milesi ◽

Anna Rangan ◽

Sara Grafenauer

Keyword(s):

Literature Review ◽

Systematic Literature Review ◽

Inflammatory Markers ◽

Disease Risk ◽

Inflammatory Marker ◽

Healthy Population ◽

Randomized Control Trials ◽

Whole Grain ◽

Randomized Control ◽

Grain Foods

Whole grain foods are rich in nutrients, dietary fibre, a range of antioxidants, and phytochemicals, and may have potential to act in an anti-inflammatory manner, which could help impact chronic disease risk. This systematic literature review aimed to examine the specific effects of whole grains on selected inflammatory markers from human clinical trials in adults. As per the Preferred Reporting Items for Systematic Reviews (PRISMA) protocol, the online databases MEDLINE, Embase, Cochrane, CINAHL, and Scopus were searched from inception through to 31 August 2021. Randomized control trials (RCTs) ≥ 4 weeks in duration, reporting ≥1 of the following: C-reactive protein (CRP), interleukin-6 (IL-6), and tumor necrosis factor (TNF), were included. A total of 31 RCTs were included, of which 16 studies recruited overweight/obese individuals, 12 had pre-existing conditions, two were in a healthy population, and one study included participants with prostate cancer. Of these 31 RCTs, three included studies with two intervention arms. A total of 32 individual studies measured CRP (10/32 were significant), 18 individual studies measured IL-6 (2/18 were significant), and 13 individual studies measured TNF (5/13 were significant). Most often, the overweight/obese population and those with pre-existing conditions showed significant reductions in inflammatory markers, mainly CRP (34% of studies). Overall, consumption of whole grain foods had a significant effect in reducing at least one inflammatory marker as demonstrated in 12/31 RCTs.

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Conversion of Unresectable to Resectable Liver Metastases from Colorectal Carcinoma Using Hepatic Arterial Chronomodulated Chemotherapy: A Case Report and Short Literature Review

Surgical Science ◽

10.4236/ss.2018.910043 ◽

2018 ◽

Vol 09 (10) ◽

pp. 358-366

Author(s):

Evgeny Y. Parnes ◽

Maria S. Sayapina ◽

Alexey A. Tryakin ◽

Mohamed Bouchahda ◽

Pasquale F. Innominato ◽

...

Keyword(s):

Case Report ◽

Colorectal Carcinoma ◽

Literature Review ◽

Liver Metastases

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Systematic Literature Review of Randomized Control Trials Assessing the Effectiveness of Nutrition Interventions in Community-Dwelling Older Adults

Journal of Nutrition Education and Behavior ◽

10.1016/j.jneb.2010.01.004 ◽

2011 ◽

Vol 43 (4) ◽

pp. 251-262 ◽

Cited By ~ 42

Author(s):

Kristofer Bandayrel ◽

Sharon Wong

Keyword(s):

Older Adults ◽

Literature Review ◽

Systematic Literature Review ◽

Community Dwelling ◽

Randomized Control Trials ◽

Nutrition Interventions ◽

Randomized Control ◽

Community Dwelling Older Adults

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Hepatic Arterial Therapy for First-Line Treatment of Unresectable Colorectal Liver Metastases: What We Know in the Wake of Two Recent Randomized Control Trials

CardioVascular and Interventional Radiology ◽

10.1007/s00270-016-1469-0 ◽

2016 ◽

Vol 40 (2) ◽

pp. 315-317

Author(s):

Olaguoke Akinwande ◽

Robert CG Martin

Keyword(s):

Liver Metastases ◽

Colorectal Liver Metastases ◽

Randomized Control Trials ◽

Line Treatment ◽

First Line ◽

Unresectable Colorectal Liver Metastases ◽

Randomized Control ◽

First Line Treatment

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Does the Time of Day at Which Endocrine Therapy Is Taken Affect Breast Cancer Patient Outcomes?

Current Oncology ◽

10.3390/curroncol28040229 ◽

2021 ◽

Vol 28 (4) ◽

pp. 2523-2528

Author(s):

Ana-Alicia Beltran-Bless ◽

Lisa Vandermeer ◽

Mohammed F. K. Ibrahim ◽

Brian Hutton ◽

Risa Shorr ◽

...

Keyword(s):

Breast Cancer ◽

Side Effects ◽

Literature Review ◽

Cancer Patient ◽

Breast Cancer Patient ◽

Endocrine Therapy ◽

Patient Outcomes ◽

Time Of Day ◽

Randomized Control Trials ◽

Randomized Control

Background: Non-compliance and non-persistence with endocrine therapy for breast cancer is common and usually related to treatment-induced side effects. There are anecdotal reports that simply changing the time of day when taking endocrine therapy (i.e., changing morning dosing to evening dosing or vice versa) can reduce side effects. Literature review: We conducted a literature review to evaluate whether changing the timing of tamoxifen and/or aromatase inhibitor administration impacted patient outcomes. No randomized control trials or prospective cohort studies that looked at time of day of endocrine therapy were identified through our review of literature from 1947 until August 2020. Conclusions: Given the rates of endocrine therapy non-compliance and non-persistence reported in the literature, ranging from 41–72% and 31–73%, respectively, simply changing the time of day when medications are taken could be an important strategy. We could identify no trials evaluating the effect of changes in timing of administration of endocrine therapy on breast cancer patient outcomes. Randomized control trials are clearly indicated for this simple and cost-effective intervention.

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