scholarly journals Calorie Restriction and Moderate-Intensity Continuous Exercise Decrease Free Fatty Acid Levels and Visceral Fat Weight on High Calorie Diet Female Mice

2021 ◽  
Keyword(s):  
Fatty Acid ◽  
Free Fatty Acid ◽  
Calorie Restriction ◽  
Visceral Fat ◽  
Moderate Intensity ◽  
Female Mice ◽  
Continuous Exercise ◽  
Calorie Diet ◽  
High Calorie Diet ◽  
High Calorie

FATTY ACID COMTENTS IN RAT ADIPOSE TISSUES UNDER ANAEROBIC EXERCISE AND HIGH-CALORIE DIETS

2019 ◽  
pp. 106-113
Author(s):  
I.Yu. Yakimovich ◽  
M.Yu. Kotlovskiy ◽  
S.V. Gusakova ◽  
V.V. Ivanov ◽  
V.N. Vasil'ev ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Fatty Acid ◽  
Unsaturation Index ◽  
Anaerobic Exercise ◽  
Adipose Tissues ◽  
Calorie Diet ◽  
Visceral Adipose ◽  
Subcutaneous Adipose ◽  
High Calorie Diet ◽  
High Calorie

The objective of the paper is to study the effects of anaerobic exercise on fatty acids percentage in adipose tissues of different localization under high-calorie diets in rats. Materials and Methods. The authors examined Wistar rats under high calorie diets (32 % fat content). In the first group the animals were not exposed to any physical exercise. In the second group rats were exposed to anaerobic physical activity, namely swimming. The percentage of 24 fatty acids (FA) and the value of 14 integrative indicators (complexes) in the depot of visceral and subcutaneous adipose tissues were determined using chromatography-mass spectrometry (Agilent Technologies, USA). Results. Anaerobic exercise led to an increase in saturated FAs in the mesenteric adipose tissues and to a decrease in unsaturated FAs, as well as to a decrease in the unsaturation index; an increase in the retroperitoneal adipose tissue of the FA sphingophospholipid substrates, FA membrane substrates, a decrease in the energy substrates, an increase of vitamin F FA substrates due to ω6 of unsaturated FAs. At the same time, a decrease in the amount of polyunsaturated FAs was observed in the subcutaneous depot, and the balance between ω3/ω6 shifted towards ω6 of unsaturated FAs. In the mesenteric and retroperitoneal adipose tissues, there was a decrease in monounsaturated FAs due to ω9 of unsaturated FAs, and the ratio of saturated FAs/monounsaturated FAs shifted towards saturated FAs. Only in retroperitoneal adipose tissues there was a decrease in ω7 of saturated FAs due to C16: 1 ω7. Conclusion. Regular anaerobic exercise and a high-calorie diet showed the most pronounced effect on FAs in visceral adipose tissues, namely in mesenteric and retroperitoneal tissues. Keywords: fatty acids, fatty acid complexes, adipose tissues, anaerobic exercise, high-calorie diet. Цель – исследовать воздействие анаэробной физической нагрузки на процентное содержание жирных кислот в жировой ткани разной локализации на фоне питания повышенной калорийности у крыс. Материалы и методы. В исследовании использовали крыс линии Wistar, находящихся на питании повышенной калорийности (с долей жира 32 %). В первой группе животных физическая нагрузка отсутствовала, крысы второй группы получали физическую нагрузку преимущественно анаэробного характера в виде плавания. Процентное содержание 24 жирных кислот (ЖК) и значение 14 интегративных показателей (комплексов) в депо висцеральной и подкожной жировой ткани определяли на хромато-масс-спектрометре (Аgilent Technologies, США). Результаты. Анаэробная физическая нагрузка привела к увеличению содержания в мезентеральной жировой ткани насыщенных ЖК (НасЖК) и снижению ненасыщенных ЖК (НЖК), а также снижению индекса ненасыщенности; увеличению в забрюшинной жировой ткани ЖК-субстратов сфингофосфолипидов, ЖК-субстратов мембран, снижению субстратов энергии, увеличению содержания ЖК-субстратов витамина F за счет ω6 НЖК. При этом в подкожном депо наблюдалось снижение суммы полиненасыщенных ЖК, а баланс ω3/ω6 сместился в сторону ω6 НЖК. В мезентериальной и забрюшинной жировой ткани отмечалось снижение содержания мононенасыщенных ЖК (МНЖК) за счет ω9 НЖК, а соотношение НасЖК/МНЖК сместилось в сторону НасЖК. Только в забрюшинной жировой ткани было установлено снижение содержания ω7 НЖК за счет С16:1 ω7. Выводы. Регулярная анаэробная физическая нагрузка на фоне питания повышенной калорийности продемонстрировала наиболее выраженное влияние в отношении ЖК в висцеральной жировой ткани, а именно в мезентериальной и забрюшинной. Ключевые слова: жирные кислоты, комплексы жирных кислот, жировая ткань, анаэробная физическая нагрузка, диета повышенной калорийности.

scholarly journals Propranolol attenuates calorie restriction- and high calorie diet-induced bone marrow adiposity

BMB Reports ◽  
2014 ◽  
Vol 47 (10) ◽  
pp. 587-592 ◽  
Author(s):  
Kyunghwa Baek ◽  
Hyun-Jung Park ◽  
Hyo Rin Hwang ◽  
Jeong-Hwa Baek
Keyword(s):  
Bone Marrow ◽  
Calorie Restriction ◽  
Marrow Adiposity ◽  
Calorie Diet ◽  
High Calorie Diet ◽  
High Calorie

scholarly journals Influence of leptin administration to pregnant female mice on obesity development, taste preferences, and gene expression in the liver and muscles of their male and female offspring

2021 ◽  
Vol 25 (6) ◽  
pp. 669-676
Author(s):  
E. I. Denisova ◽  
M. M. Savinkova ◽  
E. N. Makarova
Keyword(s):  
Gene Expression ◽  
Food Choice ◽  
Female Offspring ◽  
Taste Preferences ◽  
Male And Female ◽  
Female Mice ◽  
Pregnant Females ◽  
Calorie Diet ◽  
High Calorie Diet ◽  
High Calorie

The consumption of food rich in sugar and fat provokes obesity. Prenatal conditions have an impact on taste preferences and metabolism in the adult offspring, and this impact may manifest differently in different sexes. An increase in blood leptin level in pregnant females reduces the risk of obesity and insulin resistance in the offspring, although the mechanisms mediating this effect are unknown. Neither is it known whether maternal leptin affects taste preferences. In this study, we investigated the effect of leptin administration to pregnant mice on the development of diet-induced obesity, food choice, and gene expression in the liver and muscles of the offspring with regard to sex. Leptin was administered to female mice on days 11, 12, and 13 of pregnancy. In male and female offspring, growth rate and intake of standard chow after weaning, obesity development, gene expression in the liver and muscles, and food choice when kept on a high-calorie diet (standard chow, lard, sweet cookies) were recorded. Leptin administration to pregnant females reduced body weight in the female offspring fed on the standard diet. When the offspring were given a high-calorie diet, leptin administration inhibited obesity development and reduced the consumption of cookies only in males. It also increased the consumption of standard chow and the mRNA levels of genes for the insulin receptor and glucose transporter type 4 in the muscles of both male and female offspring. The results demonstrate that an increase in blood leptin levels in pregnant females has a sex-specific effect on the metabolism of the offspring increasing resistance to obesity only in male offspring. The mechanism underlying this effect includes a shift in food preference in favor of a balanced diet and maintenance of insulin sensitivity in muscle tissues.

scholarly journals The consequences of a high-calorie diet background before calorie restriction on skeletal muscles in a mouse model

Aging ◽  
2021 ◽  
Author(s):  
Martin Maldonado ◽  
Jianying Chen ◽  
Yang Lujun ◽  
Huiqin Duan ◽  
Mazhar Ali Raja ◽  
...  
Keyword(s):  
Mouse Model ◽  
Calorie Restriction ◽  
Skeletal Muscles ◽  
Calorie Diet ◽  
High Calorie Diet ◽  
High Calorie

The evaluation of lipid peroxidation and oxidative modification of proteins in blood serum under obesity development and the consumption of aqueous kidney beans Phaseolus vulgaris pods extract

2020 ◽  
Vol 33 (1) ◽  
pp. 38-44
Author(s):  
Alona Yurchenko ◽  
Daryna Krenytska ◽  
Olexii Savchuk ◽  
Tetiana Halenova ◽  
Natalia Raksha ◽  
...  
Keyword(s):  
Lipid Peroxidation ◽  
Oxidative Modification ◽  
Resistance Development ◽  
Oxidative Modification Of Proteins ◽  
Kidney Beans ◽  
Calorie Diet ◽  
Diet Control ◽  
High Calorie Diet ◽  
High Calorie

AbstractOur interest has focused on the investigation of the anti-obese potential of kidney beans (P. vulgaris) pods extract. In the course of the study, obesity development in rats was induced with high-calorie diet. Control and obese rats then have consumed with aqueous kidney beans (P. vulgaris) pods extract during 6 weeks (200 mg/kg). Results show that the long-term consumption of P. vulgaris pods extract can lead to the reduction of hyperglycemia and insulin resistance development. Furthermore, we saw a normalization of lipid peroxidation parameters and oxidative modification of protein due to the consumption of the kidney beans (P. vulgaris) pods extract. Our experimental data demonstrate the ability of the kidney beans (P. vulgaris) pod extracts to mitigate obesity development but the details of this mechanism remains to be not fully understood.

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