High-Sensitivity Optical-Fiber Microfluidic Chip Based on Surface Plasmon Resonance

AbstractThis research focuses on the side-polished Single-Mode Optical Fibers (SMOF) as refractive index (RI) sensor utilizing properties of Surface Plasmon Resonance. The SMOF with cladding stripped off shows a D-shaped optical fiber with high sensitivity functionalization. Here we show silver protected by graphene oxide (GO) as viable candidates. A few layers of GO on top of silver thin layer were applied as a material to overcome silver coating degradation process. This silver/GO sensor was characterized using various RIs of analyte likely deionized water and alcohol solutions. Sensor with GO has shown fast response and high sensitivity in respect of RI, where sensitivity increases in range from 1.30 to 1.34 RIU (refractive index unit). This device shows highest sensitivity of up to 833.33 nm/ RIU. The polishing process using SMOF stops at few microns above the core of the fiber with the drop of output power fixed to be 1 dB as an indication to standardize the amount of cladding been removed. The thickness of 30 nm Ag was deposited using electron beam evaporation method on D-shaped optical fiber with subsequent protected layer of GO in solutions form. The use of COMSOL Multiphysics has also been carried out to observe numerical findings. The response of the GO has shown a sensitivity improvement which proves new promising approaches for the newly developed sensors.

Download Full-text

High Sensitivity of Phase-based Surface Plasmon Resonance in Nano-cylinder Array

PIERS Online ◽

10.2529/piers071220003006 ◽

2008 ◽

Vol 4 (7) ◽

pp. 746-750 ◽

Cited By ~ 3

Author(s):

Bing-Hung Chen ◽

Yih-Chau Wang ◽

Jia-Hng Lin

Keyword(s):

Surface Plasmon Resonance ◽

Surface Plasmon ◽

Plasmon Resonance ◽

High Sensitivity ◽

Cylinder Array

Download Full-text

Surface Plasmonic Sensors: Sensing Mechanism and Recent Applications

Sensors ◽

10.3390/s21165262 ◽

2021 ◽

Vol 21 (16) ◽

pp. 5262

Author(s):

Qilin Duan ◽

Yineng Liu ◽

Shanshan Chang ◽

Huanyang Chen ◽

Jin-hui Chen

Keyword(s):

Surface Plasmon Resonance ◽

Optical Fiber ◽

Surface Plasmon ◽

Optical Sensors ◽

Plasmon Resonance ◽

2D Materials ◽

Localized Surface Plasmon ◽

Plasmonic Sensors ◽

Hyperbolic Dispersion ◽

Challenges And Opportunities

Surface plasmonic sensors have been widely used in biology, chemistry, and environment monitoring. These sensors exhibit extraordinary sensitivity based on surface plasmon resonance (SPR) or localized surface plasmon resonance (LSPR) effects, and they have found commercial applications. In this review, we present recent progress in the field of surface plasmonic sensors, mainly in the configurations of planar metastructures and optical-fiber waveguides. In the metastructure platform, the optical sensors based on LSPR, hyperbolic dispersion, Fano resonance, and two-dimensional (2D) materials integration are introduced. The optical-fiber sensors integrated with LSPR/SPR structures and 2D materials are summarized. We also introduce the recent advances in quantum plasmonic sensing beyond the classical shot noise limit. The challenges and opportunities in this field are discussed.

Download Full-text

Design and validation of fiber optic localized surface plasmon resonance sensor for thyroglobulin immunoassay with high sensitivity and rapid detection

Scientific Reports ◽

10.1038/s41598-021-95375-y ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Hyeong-Min Kim ◽

Dae Hong Jeong ◽

Ho-Young Lee ◽

Jae-Hyoung Park ◽

Seung-Ki Lee

Keyword(s):

Surface Plasmon Resonance ◽

Optical Fiber ◽

Surface Plasmon ◽

Plasmon Resonance ◽

Localized Surface Plasmon Resonance ◽

Optical Fiber Sensor ◽

Fiber Sensor ◽

Localized Surface Plasmon ◽

Simple Method ◽

Resonance Sensor

AbstractA simple optical fiber sensor based on localized surface plasmon resonance was constructed for direct and rapid measurement of thyroglobulin (Tg). Specific tests for Tg in patients that have undergone thyroidectomy are limited because of insufficient sensitivity, complicated procedures, and in some cases, a long time to yield a result. A sensitive, fast, and simple method is necessary to relieve the psychological and physical burden of the patient. Various concentrations of Tg were measured in a microfluidic channel using an optical fiber sensor with gold nanoparticles. The sensor chip has a detection limit of 93.11 fg/mL with no specificity for other antigens. The potential applicability of the Tg sensing system was evaluated using arbitrary samples containing specific concentrations of Tg. Finally, the sensor can be employed to detect Tg in the patient’s serum, with a good correlation when compared with the commercial kit.

Download Full-text