scholarly journals GRAVIS MYASTHENIA – ACUTE ERYTHROBLASTIC LEUKEMIA CORRELATION

2017 ◽  
Vol 64 (2) ◽  
pp. 147-150
Author(s):  
Angela Mirela Soare ◽  
◽  
Cezar Mihai Popescu ◽  

Myasthenia Gravis is a chronic autoimmune neuromuscular disorder that is characterized by fluctuating weakness of the voluntary muscle groups. It occurs in all races, at any age (especially under 40 or over 60), both genders, with a prevalence of 20/100,000 population in the United States. About 15 percent of patients with myasthenia gravis have thymomas, much rarely another solid tumor, thyroid dysfunction and more often another autoimmune condition, such as rheumatoid arthritis, lupus, Biermer anaemia. We present a 72 year-old male patient with ocular myasthenia gravis treated with cholinesterase inhibitors, that, after many laboratory exams, was diagnosed with acute erythroblastic leukemia, a very rare clinical association.

2018 ◽  
Vol 14 (3) ◽  
pp. 179-180
Author(s):  
Marta Novella-Navarro ◽  
Juan Salvatierra-Ossorio ◽  
María del Mar Muñoz-Gómez ◽  
María Pavo-Blanco

2018 ◽  
Vol 02 (01) ◽  
pp. E51-E55
Author(s):  
Lukas Kirzinger ◽  
Sophie Schötz ◽  
Berthold Schalke

AbstractPure ocular myasthenia was always described as a separate entity in historical publications. More than 50% of patients develop generalized symptoms in the course of the disease. Therefore pure ocular symptoms can be the beginning of generalized myasthenia, nevertheless there is a small group of patients who suffer lifelong purely ocular symptoms. The basis, therefore, seems to be special immunological, biochemical and pathophysiological mechanisms leading to specific local changes of the neuromuscular junction. The diagnostic procedure is hampered as antibodies against acethylcholine receptors and MuSK can be demonstrated in less than 50% of these patients. Therapy of pure ocular myasthenia does not differ fundamentally from other subgroups of myasthenia gravis and is implemented with cholinesterase inhibitors, steroids and common immunosuppressants. Thymomectomy is not recommended in general, but randomized controlled studies are lacking.


2016 ◽  
Vol 22 ◽  
pp. 277-278
Author(s):  
Lima Lawrence ◽  
Aleida Rodriguez ◽  
Tahira Yasmeen ◽  
Erin Drever

Author(s):  
Gordon Plant

Ocular myasthenia is not the most severe form of myasthenia but it might cause certain difficulties to diagnose. In this article, we shall discuss the clinical presentations of ocular myasthenia, its differential diagnostics, examinations and management. Keywords: ocular myasthenia gravis, diagnosis, examination, management.


2021 ◽  
Vol 118 ◽  
pp. 12-19
Author(s):  
Kristen S. Fisher ◽  
Jason Gill ◽  
Hannah F. Todd ◽  
Michael B. Yang ◽  
Michael A. Lopez ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Thanchat Jienmaneechotchai ◽  
Supanut Apinyawasisuk ◽  
Supharat Jariyakosol ◽  
Parima Hirunwiwatkul

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