scholarly journals Direct-current Stimulation and Multi-electrode Array Recording of Seizure-like Activity in Mice Brain Slice Preparation

10.3791/53709 ◽  
2016 ◽  
Author(s):  
Hsiang-Chin Lu ◽  
Wei-Jen Chang ◽  
Wei-Pang Chang ◽  
Bai-Chuang Shyu
Keyword(s):  
Direct Current ◽  
Brain Slice ◽  
Electrode Array ◽  
Slice Preparation ◽  
Direct Current Stimulation ◽  
Mice Brain ◽  
Brain Slice Preparation ◽  
Multi Electrode Array

23. A new adult rat brain slice preparation for ex vivo NMR spectroscopy studies of stroke

1994 ◽  
Vol 52 (1) ◽  
pp. A11
Author(s):  
M.T. Espanol ◽  
L. Litt ◽  
L.-H. Chang ◽  
T.L. James ◽  
P.R. Weinstein ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Rat Brain ◽  
Brain Slice ◽  
Ex Vivo ◽  
Slice Preparation ◽  
Adult Rat ◽  
Adult Rat Brain ◽  
Spectroscopy Studies ◽  
Rat Brain Slice ◽  
Brain Slice Preparation

Electrophysiological Study of the Neostriatum in Brain Slice Preparation

Brain Slices ◽  
1984 ◽  
pp. 285-296 ◽  
Author(s):  
S. T. Kitai ◽  
H. Kita
Keyword(s):  
Brain Slice ◽  
Electrophysiological Study ◽  
Slice Preparation ◽  
Brain Slice Preparation

The neural circuitry of the neocortex examined in the in vitro brain slice preparation

1982 ◽  
Vol 243 (1) ◽  
pp. 35-47 ◽  
Author(s):  
Christopher Shaw ◽  
Timothy J. Teyler
Keyword(s):  
Brain Slice ◽  
Neural Circuitry ◽  
Slice Preparation ◽  
Brain Slice Preparation

Convergent inputs to Octopus oculomotor neurones demonstrated in a brain slice preparation

1991 ◽  
Vol 121 (1-2) ◽  
pp. 215-218 ◽  
Author(s):  
Roddy Williamson ◽  
Bernd U. Budelmann
Keyword(s):  
Brain Slice ◽  
Slice Preparation ◽  
Brain Slice Preparation

Nicotinic and muscarinic receptor-evoked depolarizations recorded from a novel cortical brain slice preparation

1995 ◽  
Vol 34 (10) ◽  
pp. 1289-1296 ◽  
Author(s):  
I.P. Chessell ◽  
P.P.A. Humphrey
Keyword(s):  
Muscarinic Receptor ◽  
Brain Slice ◽  
Slice Preparation ◽  
Brain Slice Preparation

Effect of anoxia on intracellular and extracellular potassium activity in hypoglossal neurons in vitro

1991 ◽  
Vol 66 (1) ◽  
pp. 103-111 ◽  
Author(s):  
C. Jiang ◽  
G. G. Haddad
Keyword(s):  
Brain Slice ◽  
Neuronal Response ◽  
Extracellular Potassium ◽  
Intracellular Recordings ◽  
High Concentration ◽  
Slice Preparation ◽  
Adult Rats ◽  
Short Period ◽  
Brain Slice Preparation

1. A brain slice preparation was used to study the hypoglossal (XII) neuronal response to anoxia. Both intra- and extracellular potassium activities (K+i,K+o) were measured by the use of ion-selective microelectrodes, and K+ flux was assessed by the use of pharmacologic blockers. 2. Extracellular recordings showed that a short period of anoxia (4 min) induced an increase in K+o of 26.4 +/- 7.5 mM (mean +/- SD, n = 20) in the XII nucleus of adult rats. 3. Intracellular recordings (n = 31) in XII neurons showed a substantial decrease in K+i during anoxia. Fourteen neurons were analyzed in detail and these showed that XII neurons depolarized to -25.3 +/- 7.7 mV, whereas K+i dropped from 93.6 +/- 14.9 to 32 +/- 9.0 mM. These results strongly suggested that K+ is lost from XII neurons during anoxia. 4. Although the extracellular space (ECS) shrank by approximately 50% during anoxia, the possibility that the increase in K+o and decrease in K+i were mainly caused by shrinkage of the ECS and swelling of intraneuronal space was excluded to a great degree because the changes in K+i and K+o during anoxia were relatively very large. 5. To study the mechanisms by which K+ is lost from XII neurons, we used several pharmacologic blockers. High concentration of ouabain (10 mM) and strophanthidin (80 microM) increased K+o from baseline (3-4 mM) to 40.9 +/- 2.5 mM (n = 6) but did not abolish an additional anoxia-induced increase in K+o, suggesting that mechanisms other than Na(+)-K(+)-adenosine triphosphatase inhibition were also responsible for the anoxia-induced K+ leakage.(ABSTRACT TRUNCATED AT 250 WORDS)

scholarly journals Optimization of focality and direction in dense electrode array transcranial direct current stimulation (tDCS)

2016 ◽  
Vol 13 (3) ◽  
pp. 036020 ◽  
Author(s):  
Seyhmus Guler ◽  
Moritz Dannhauer ◽  
Burak Erem ◽  
Rob Macleod ◽  
Don Tucker ◽  
...  
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Electrode Array ◽  
Direct Current Stimulation

Adenosine inhibits locus coeruleus neurons: An intracellular study in a rat brain slice preparation

1986 ◽  
Vol 366 (1-2) ◽  
pp. 364-368 ◽  
Author(s):  
Sarah A. Shefner ◽  
Tsai H. Chiu
Keyword(s):  
Locus Coeruleus ◽  
Rat Brain ◽  
Brain Slice ◽  
Slice Preparation ◽  
Intracellular Study ◽  
Rat Brain Slice ◽  
Brain Slice Preparation
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