scholarly journals Clinico-Histological presentation of Head and Neck Lesions in a Tertiary Care Hospital

2021 ◽  
Vol 25 (1) ◽  
pp. 21-25
Author(s):  
Mohammad Sajjad Kattak ◽  
Abdul Ghafoor ◽  
Rafi Ullah ◽  
Asif Mehmmod ◽  
Mohammad Iqbal ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Basal Cell ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Malignant Lesions

Objective: This study aimed to see the clinical presentation and histological pattern of various head and neck lesions.Materials and Methods: This descriptive study was conducted in the Department of Pathology, Bannu Medical College in association with the Department of Surgery and ENT, Khalifa Gul Nawaz Teaching Hospital, Bannu. A total of 184 cases of head and neck lesions biopsy were subjected to histopathological diagnosis. Patients' age, gender, anatomical location, and other relevant necessary clinical findings were recorded on an already designed proforma. All biopsies were received in 10% buffered formalin, fixed overnight, and processed for histopathological examination and diagnosis. Inclusion criteria were patients with head and neck lesions including skin, salivary gland, lymph node, and oral cavity of any age and gender. Exclusion criteria were thyroid, nasal cavity lesions, autolysed, and insufficient biopsy specimen. Results: In this study, the mean age was 28.58 ± 17.34 years, and the age range was from 10 to 80 years. The male-to-female ratio was 1.3:1. The most common age group was 36-45 years followed by 46-55 years and 26-35 years etc. The most common inflammatory lesion was granulomatous lymphadenitis 14.67% followed by reactive lymphoid hyperplasia 9.23%. Common benign lesions were pleomorphic adenoma 5.97% followed by lipoma and hemangioma 3.80% and 3.26% respectively. Amongst malignant lesions basal cell carcinoma 23.91% of the face was the commonest lesion followed by squamous cell carcinoma 22.28% of the oral cavity. Conclusion: This study show spectrum of lesions from inflammatory to benign and malignant, occurring in the head and neck region. Malignant lesions are more common as compared to benign and inflammatory lesions, basal cell carcinoma of the skin is the commonest malignant lesion followed by squamous cell carcinoma of the skin and oral cavity.

Geographic Pathology of Skin Cancer

1999 ◽  
Vol 3 (3) ◽  
pp. 120-122
Author(s):  
Robert Jackson
Keyword(s):  
Squamous Cell Carcinoma ◽  
Skin Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Basal Cell ◽  
Sun Exposure

Background: The development of knowledge concerning the role of sun exposure in causing skin cancer has been a gradual one. Objective: This article reviews the article by Urbach who used manikin coated with an ultraviolet dosimeter to see exactly where on the head and neck the exposure was greatest. Conclusion: Urbach showed that the areas of greatest sun exposure on his manikins corresponded with the location of 95% of squamous cell carcinoma and 66% of basal cell carcinoma. He also clearly showed the importance of scattered sky and reflected radiation.

scholarly journals A STUDY OF MALIGNANT LESIONS OF VULVA

2020 ◽  
pp. 1-2
Author(s):  
Mareeswari. M ◽  
Anitha Catherine Preethima.T
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Genital Tract ◽  
Vulvar Cancer ◽  
Malignant Lesion ◽  
Clinical Staging ◽  
Malignant Lesions

INTRODUCTION: Vulvar cancer is uncommon and relatively rare. Vulvar cancers do not always go through the preinvasive stages before developing into invasive cancer. It represents 1-4% of malignancies of female genital tract. Most common among the valvar cancer is squamous cell carcinoma (90%). Less common is melanoma, basal cell carcinoma, Adenocarcinoma and sarcoma which account for 10%. AIM: To determine the prevalence among genital tract malignancies, histopathological pattern, Staging, modality of treatment and post operative complications of malignant lesion of vulva. METHODS: It is a Cross sectional study carried out in Madurai medical college. The medical records of all women with malignant lesion of vulve between January 2009 to September 2011 were reviewed. From the case record, the patient profile, complaints, associated medical complications were noted. The record of investigations, treatment modalities and postoperative complications were studied. The diagnosis was confirmed by biopsy and clinical staging was done and planned for treatment. RESULTS: 10 cases of malignant lesions of vulva were noted during the period. Prevalence is about 0.8% of all genital tract malignancies. Age wise distribution reveals 60 % of our cases were above 60 years of age. 80% of our prevalence observed in postmenopausal women. Most patient had complaints of pruritis (100%), ulcer(70%), swelling(30%). Had associated medical complication of diabetic (40%), hypertensive (20%). Histopathologically the most predominant type is squamous cell carcinoma (60%), malignant melanoma (10%), basal cell carcinoma(10%), Baseloid squamous cell carcinoma(10%), Vulvar intraepithelial neoplasia (10%). Stage wise classification of squamous cell carcinoma –stage 0-12.5%, stage2- 37.5%, stage 3- 37.5%, stage 4 – 12.5%. CONCLUSION: Most cases above 60 yrs of age and 80% of our cases shows squamous cell carcinoma. Prevalence is about 0.8% of all genital tract malignancies. Most of the cases reported in the advanced stage of vulvar cancer. Biopsy is the method to confirm the diagnosis, Early diagnosis has a good prognosis . five year survival in stage 1 is 90%.

scholarly journals Study of histomorphological spectrum of eyelid lesions

2021 ◽  
Vol 11 (1) ◽  
pp. 1790-1802
Author(s):  
Reshmi Shrestha ◽  
Gita Sayami
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Basal Cell ◽  
Sebaceous Carcinoma ◽  
Epidermal Cyst ◽  
Wide Range ◽  
Malignant Lesions ◽  
Eyelid Lesions

Background: Eyelid pathologies are the most common surgical specimens encountered among all of the ophthalmic lesions and constitute a wide range of diseases by their unique histologic features. This study aims to find out the histopathological spectrum of eyelid lesions, their demographic distribution, and preferential location prevalent in our community.Materials and Methods: This is an observational study in which we retrospectively evaluated the data of 692 patients retrieved from the histopathology department of National Reference Laboratory, Kathmandu, from May 2016 to April 2019.Results: A total of 701 histologic diagnoses comprised of benign, precursor, and malignant lesions and accounted for 86.6%, 2.6%, and 10.8% respectively with preponderance in females. The common benign lesions included melanocytic nevus (17.7%), epidermal cyst (11%), hemangioma (8.9%), dermoid cyst (8.2%), chalazion (6.7%), and squamous papilloma (6.4%). Tumour of epidermal origin was the most common neoplastic lesion accounting for 31.2%. Basal cell carcinoma (50%) followed by sebaceous carcinoma (27.6%) and squamous cell carcinoma (14.5%) constituted the majority of malignant lesions prevalent above the age of 60 years with the preferential site of the upper eyelid for basal cell carcinoma and squamous cell carcinoma; and lower eyelid for sebaceous carcinoma.Conclusions: Benign eyelid lesions are more prevalent than malignant ones with overall female  preponderance. Epidermal tumours are common among neoplasms. A malignant tumour, a disease of  an elderly individual, is predominated by basal cell carcinoma followed by sebaceous carcinoma, an aggressive tumour with a high recurrence rate in our population.

Epidemiology of basal cell carcinoma and squamous cell carcinoma of the pinna

2001 ◽  
Vol 115 (2) ◽  
pp. 85-86 ◽  
Author(s):  
Ijaz Ahmad ◽  
A. R. Das Gupta
Keyword(s):  
Squamous Cell Carcinoma ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Basal Cell ◽  
Skin Area ◽  
Neck Area ◽  
Diagnosis Of Cancer ◽  
Overall Ratio

This is a retrospective study designed to compare the incidence of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) in the head and neck skin area with special reference to the pinna.The results showed 426 patients had 460 cutaneous malignancies in the head and neck area, managed by four specialities (ENT, Dermatology, General Surgery and GPs) over the period 1994–99. The lesions comprised 375 (80.47 per cent) BCC and 85 (18.47 per cent) SCC. In cases of BCC the facial areas were commonly involved (88 per cent), whilst SCC was almost equally distributed between the most (face, forehead and nose) and least exposed areas (pinna and scalp). The overall ratio of BCC to SCC remained four to one in the head and neck area. In 41 patients with 51 lesions over the pinna there were 29 (56.8 per cent) BCC and 22 (43.1 per cent) SCC hence the ratio was 1.3 to 1 for this site.We conclude that in the case of a suspicious lesion over the pinna, the risk of SCC is comparatively much higher. With increasing awareness of early and quick diagnosis of cancer cases, it is recommended that these patients should be referred urgently to prevent the significant morbidity associated with invasive SCC.

scholarly journals Profile of oral cavity neoplastic lesions: two year pilot study at tertiary care centre

2020 ◽  
Vol 6 (6) ◽  
pp. 1107
Author(s):  
Manish Munjal ◽  
Ramandeep Kaur ◽  
Porshia Rishi ◽  
Nitika Tuli ◽  
Harjinder Singh ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Survival Rate ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Histopathological Diagnosis ◽  
Female Ratio ◽  
Neoplastic Lesions

<p class="abstract"><strong>Background:</strong> In India 53,251 new head and neck cancer cases are diagnosed every year. Benign tumours are more frequently in the oral cavity than oropharynx.</p><p class="abstract"><strong>Methods:</strong> The prospective study was carried out in the Department of Otolaryngology and Head and Neck Surgery, Dayanand Medical College and Hospital, Ludhiana, over a period of two and half years, comprised of 66 cases of head and neck neoplasia. The demographic, gender profile, clinical presentation, histopathological diagnosis, therapeutic modality undertaken and post op complications of neoplastic lesions of the oral cavity were studied. follow up was done for 6 months. The therapeutic modalities included surgery, radiotherapy and chemotherapy as per the stage of the lesion.</p><p class="abstract"><strong>Results:</strong> Incidence of oral cancer is 13.6% among head and neck neoplasms over a period of 2 years (2011-2012). The overall male to female ratio was 1:1.25, among benign was 1:1 and among malignant was 1:1.3. Benign oral cavity tumors were managed surgically with wide excision. Out of 7, 4 (44%) malignant oral cavity tumor patient experienced difficulty in swallowing. Three (43%) out of 4 squamous cell carcinoma patients complained of difficulty in speaking, which is commonly seen in post-glossectomy patients. The survival rate for 6 months follows up, was 100%.</p><p class="abstract"><strong>Conclusions:</strong> Squamous cell carcinoma is the commonest oral cavity neoplasia. At post treatment follow up period of 6 months survival rate of benign neoplasia is better than malignant neoplasia.</p>

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