scholarly journals Present status and future direction of clinical trials in advanced endometrial carcinoma

2008 ◽  
Vol 19 (3) ◽  
pp. 157 ◽  
Author(s):  
Howard D. Homesley
Keyword(s):  
Clinical Trials ◽  
Endometrial Carcinoma ◽  
Present Status ◽  
Future Direction

Present Status and Future Direction of NIRS-IVUS Multimodality Direct Coronary Imaging

2015 ◽  
Vol 8 (7) ◽  
Author(s):  
Ivan D. Hanson ◽  
James A. Goldstein ◽  
Simon R. Dixon ◽  
Amr E. Abbas ◽  
Robert D. Safian ◽  
...  
Keyword(s):  
Present Status ◽  
Coronary Imaging ◽  
Future Direction

scholarly journals Analysis of Clinical Trials on Therapies for Prostate Cancer in Mainland China and Globally from 2010 to 2020

2021 ◽  
Vol 11 ◽  
Author(s):  
Kun Chen ◽  
Kehua Jiang ◽  
Lannan Tang ◽  
Xiaolong Chen ◽  
Jianxin Hu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Clinical Trials ◽  
Drug Targets ◽  
Checkpoint Inhibitors ◽  
Mainland China ◽  
World Population ◽  
Large Patient ◽  
Future Direction ◽  
Long Acting ◽  
Targeted Chemotherapeutics

The overall aging of the world population has contributed to the continuous upward trend in the incidence of prostate cancer (PC). Trials on PC therapy have been extensively performed, but no study has analyzed the overall trends and characteristics of these trials, especially for those carried out in China. This study aimed to provide insights on the future direction of drug development in PC, thus supplying essential supportive data for stakeholders, including researchers, patients, investors, clinicians, and pharmaceutical industry. The details of the clinical trials of drug therapies for PC during January 1, 2010, to January 1, 2020, were collected from Pharmaprojects. A total of 463 clinical trials on different therapies with 132 different drugs were completed. The long-acting endocrine therapy with few side effects, radiotherapy combined with immune checkpoint inhibitors, gene-targeted chemotherapeutics, and novel immunotherapeutic products changed the concept of PC treatment. In mainland China, 31 trials with 19 drugs have been completed in the 10 assessment years. China has initiated a few trials investigating a limited number of drug targets, centered in a markedly uneven geographical distribution of leading clinical trial units; hence, the development of PC drugs has a long way to go. Given the large patient pool, China deserves widespread attention for PC drug research and development. These findings might have a significant impact on scientific research and industrial investment.

Antiepileptic drugs in clinical trials and future direction

2011 ◽  
pp. 54-63
Author(s):  
Alberto Verrotti ◽  
Chiara Cirillo ◽  
Giulia Loiacono
Keyword(s):  
Clinical Trials ◽  
Antiepileptic Drugs ◽  
Future Direction

TU-A-213AB-01: Dosimetry for Ir-192 HDR Brachytherapy - Present Status and Future Direction

2012 ◽  
Vol 39 (6Part22) ◽  
pp. 3884-3885
Author(s):  
L DeWerd ◽  
J Seuntjens ◽  
M Rivard ◽  
M McEwen
Keyword(s):  
Present Status ◽  
Hdr Brachytherapy ◽  
Future Direction

Clinical Trials in Orthopaedics and the Future Direction of Clinical Investigations for Femoroacetabular Impingement

2013 ◽  
Vol 21 (suppl) ◽  
pp. S47-S52 ◽  
Author(s):  
J. C. Clohisy ◽  
Y.-J. Kim ◽  
J. Lurie ◽  
S. Glyn-Jones ◽  
P. Wall ◽  
...  
Keyword(s):  
Clinical Trials ◽  
Femoroacetabular Impingement ◽  
Clinical Investigations ◽  
The Future ◽  
Future Direction

Integrative Medicine and Prospective Research on CAM

2017 ◽  
pp. 272-301
Author(s):  
Mayuree Tangkiatkumjai ◽  
Annalisa Casarin
Keyword(s):  
Clinical Trials ◽  
Integrative Medicine ◽  
Randomised Controlled Trials ◽  
Controlled Trials ◽  
Pragmatic Clinical Trials ◽  
Alternative Approaches ◽  
Research Study Design ◽  
Prospective Research ◽  
Future Direction ◽  
Randomised Controlled

There is a link between integrative medicine (IM) and prospective research on complementary and alternative medicine (CAM). IM is the future direction of CAM and research is needed to support clinical practice. Meaning of IM, proposed models of IM, and existing research on IM will be presented. Prospective research on CAM will cover methodologies presenting randomised controlled trials, harms studies of CAM in kidney disease, and a gap of CAM research. Study design and outcome measures are current challenges in CAM/IM research. Several networks of CAM research worldwide are still working on them and have proposed possible alternative approaches, such as pragmatic clinical trials and cohort multiple randomised controlled trials. These approaches would solve some limitations of randomised controlled trials in CAM research.

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