scholarly journals Atypical presentation of Middle East respiratory syndrome coronavirus in a Lebanese patient returning from Saudi Arabia

2018 ◽  
Vol 12 (09) ◽  
pp. 808-811 ◽  
Author(s):  
Saeed El Zein ◽  
Jinane Khraibani ◽  
Nada Zahreddine ◽  
Rami Mahfouz ◽  
Nada Ghosn ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Middle East ◽  
Medical Center ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
American University ◽  
American University Of Beirut ◽  
Persistent Symptoms ◽  
First Case ◽  
Health Organization

Around 2090 confirmed cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) from 27 countries have been reported to the World Health Organization (WHO) between September 2012 and October 2017, the majority of whom occurring in countries in the Arabian Peninsula, mainly in Saudi Arabia. MERS- CoV can have atypical and misleading presentations resulting in delays in diagnosis and is associated with a high mortality rate especially in elderly patients with multiple comorbidities. Herein, we present the first case of confirmed MERS-CoV infection diagnosed at the American University of Beirut Medical Center (AUBMC) - Lebanon in June 2017 presenting without any respiratory symptoms. This is the second confirmed case of MERS-CoV infection in Lebanon since 2014. The first case presented with a febrile respiratory infection with persistent symptoms despite antibiotic treatment.

scholarly journals Middle East Respiratory Syndrome

2016 ◽  
Vol 8 (1) ◽  
Author(s):  
Novie H. Rampengan
Keyword(s):  
Saudi Arabia ◽  
Middle East ◽  
World Health Organization ◽  
Antiviral Agents ◽  
Supportive Therapy ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Infected People ◽  
Corona Virus ◽  
Health Organization

Abstract: Middle East Respiratory Syndrome (MERS) is a respiratory disease caused by Corona virus (MERS-CoV). This virus was first reported in 2012 in Saudi Arabia. World Health Organization (WHO) reported that until June 2015 there were 26 countries infected by MERS-CoV with a total of 1,334 laboratory confirmed cases of MERS-CoV infection and 471 deaths. According to WHO as many as 75% of MERS-CoV cases are secondary cases, obtained from other infected people. In mid 2015 it is reported that MERS-CoV attacked South Korea with 172 confirmed cases of MERS-CoV and 27 deaths. There are no approved antiviral agents for the treatment of MERS-CoV infection or vaccine available for the prevention of MERS-CoV. MERS cases are treated with supportive therapy such as hydration, antipyretics, analgesics, respiratory support, and antibiotics in case of secondary infectionKeywords: Middle East Respiratory Syndrome, Corona virus, treatmentAbstrak: Middle East Respiratory Syndrome (MERS) merupakan penyakit saluran napas yang disebabkan oleh Corona virus (MERS-CoV). Virus ini pertama kali dilaporkan pada tahun 2012 di Arab Saudi. WHO melaporkan bahwa sampai Juni 2015 terdapat 26 negara terinfeksi MERS-CoV dengan total 1.334 kasus yang dikonfirmasi laboratorium terinfeksi MERS-CoV dan 471 kematian. Menurut WHO sebanyak 75% dari kasus MERS-CoV merupakan kasus sekunder, yaitu diperoleh dari orang lain yang terinfeksi. Pada pertengahan tahun 2015 dilaporkan MERS-CoV menyerang Korea Selatan dengan 172 kasus yang dikonfirmasi laboratorium terinfeksi MERS-CoV dan 27 kematian. Belum ada antivirus yang disetujui untuk pengobatan infeksi MERS-CoV atau vaksin yang tersedia untuk pencegahan MERS-CoV. Penanganan MERS-CoV dengan terapi suportif berupa hidrasi, antipiretik, analgetik, bantuan pernapasan, dan antibiotik bila terjadi infeksi sekunder.Kata kunci: Middle East Respiratory Syndrome, Corona virus, penanganan

scholarly journals The Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Outbreak at King Abdul-Aziz Medical City-Riyadh from Emergency Medical Services Perspective

2020 ◽  
Vol 35 (4) ◽  
pp. 457-461
Author(s):  
Abdullah Alabdali ◽  
Kharsan Almakhalas ◽  
Faisal Alhusain ◽  
Saad Albaiz ◽  
Khalid Almutairi ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Middle East ◽  
Emergency Medical Services ◽  
Lessons Learned ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Medical Services ◽  
Emergency Medical ◽  
Medical City ◽  
Health Organization

AbstractMiddle East Respiratory Syndrome Coronavirus (MERS-CoV) is a form of an infectious respiratory disease, discovered in November 2012 in Saudi Arabia. According to the World Health Organization (WHO; Geneva, Switzerland) reports, a total of 2,519 laboratory-confirmed cases and 866 MERS-CoV-related deaths were recorded as of March 5, 2016.1 The majority of reported cases originated from Saudi Arabia (2,121 cases). Also, MERS-CoV is believed to be of zoonotic origin and has been linked to camels in the Arabian area.1,2 In this report, the authors discuss the lessons learned from the MERS-CoV outbreak at King Abdul-Aziz Medical City-Riyadh (KAMC-R) from August through September 2015 from the Emergency Medical Services (EMS) perspective. The discussion includes the changes in policies and paramedic’s practice, the training and education in infection control procedures, and the process of transportation of these cases. The authors hope to share their experience in this unique situation and highlight the preparedness and response efforts that took place by the division of EMS during the outbreak.

scholarly journals Women and HIV/AIDS

1970 ◽  
pp. 14-17
Author(s):  
Randa Abul-Husn
Keyword(s):  
Middle East ◽  
World Health Organization ◽  
Control Programme ◽  
World Health ◽  
Ministry Of Health ◽  
First Case ◽  
The World ◽  
Aids Related Complex ◽  
Women And Hiv ◽  
Health Organization

The first case of AIDS was reported in Lebanon in 1988. As of July 1994, 2,402 cases of AIDS, 398 ARC (AIDS Related Complex), and 8,423 HN positive cases were reported in the region of the Middle East. The disease is heavily underreported and under-estimated, according to the National AIDS Control Programme in Lebanon. The NACP was established in 1989 by the World Health Organization and the Lebanese Ministry of Health.

Coronaviruses: HCoV, SARS-CoV, MERS-CoV, and COVID-19

2020 ◽  
Author(s):  
Michael G. Ison
Keyword(s):  
Middle East ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Control And Prevention ◽  
The Common ◽  
Upper Respiratory ◽  
Polymerase Chain ◽  
Health Organization

Coronaviruses (CoVs) are a group of viral pathogens that infect mammals and birds. The presentation in humans is typically that of a mild upper respiratory tract infection, similar to the common cold. However, in recent years, dramatic attention has arisen for more lethal members of this viral family (e.g., severe acute respiratory syndrome [SARS-CoV], Middle East respiratory syndrome [MERS-CoV], and coronavirus disease 2019 [COVID-19]). The epidemiology, clinical presentation, diagnosis, and management of these viruses are discussed in this review. Importantly, new guideline tables from the Centers for Disease Control and Prevention, as well as the World Health Organization are provided at the conclusion of the review. This review contains 12 tables, 3 figure and 48 references. Keywords: Coronavirus, severe acute respiratory distress syndrome (SARS), Middle East respiratory syndrome (MERS), COVID-19, respiratory infection, antiviral, real-time polymerase chain reaction

Coronaviruses: HCoV, SARS-CoV, MERS-CoV, and COVID-19

2020 ◽  
Author(s):  
Michael G. Ison
Keyword(s):  
Middle East ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Control And Prevention ◽  
The Common ◽  
Upper Respiratory ◽  
Polymerase Chain ◽  
Health Organization

Coronaviruses (CoVs) are a group of viral pathogens that infect mammals and birds. The presentation in humans is typically that of a mild upper respiratory tract infection, similar to the common cold. However, in recent years, dramatic attention has arisen for more lethal members of this viral family (e.g., severe acute respiratory syndrome [SARS-CoV], Middle East respiratory syndrome [MERS-CoV], and coronavirus disease 2019 [COVID-19]). The epidemiology, clinical presentation, diagnosis, and management of these viruses are discussed in this review. Importantly, new guideline tables from the Centers for Disease Control and Prevention, as well as the World Health Organization are provided at the conclusion of the review. This review contains 12 tables, 3 figure and 48 references. Keywords: Coronavirus, severe acute respiratory distress syndrome (SARS), Middle East respiratory syndrome (MERS), COVID-19, respiratory infection, antiviral, real-time polymerase chain reaction

Coronaviruses: HCoV, SARS-CoV, MERS-CoV, and COVID-19

2020 ◽  
Author(s):  
Michael G. Ison
Keyword(s):  
Middle East ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Control And Prevention ◽  
The Common ◽  
Upper Respiratory ◽  
Polymerase Chain ◽  
Health Organization

Coronaviruses (CoVs) are a group of viral pathogens that infect mammals and birds. The presentation in humans is typically that of a mild upper respiratory tract infection, similar to the common cold. However, in recent years, dramatic attention has arisen for more lethal members of this viral family (e.g., severe acute respiratory syndrome [SARS-CoV], Middle East respiratory syndrome [MERS-CoV], and coronavirus disease 2019 [COVID-19]). The epidemiology, clinical presentation, diagnosis, and management of these viruses are discussed in this review. Importantly, new guideline tables from the Centers for Disease Control and Prevention, as well as the World Health Organization are provided at the conclusion of the review. This review contains 12 tables, 3 figure and 48 references. Keywords: Coronavirus, severe acute respiratory distress syndrome (SARS), Middle East respiratory syndrome (MERS), COVID-19, respiratory infection, antiviral, real-time polymerase chain reaction

Coronaviruses: HCoV, SARS-CoV, MERS-CoV, and COVID-19

2020 ◽  
Author(s):  
Michael G. Ison
Keyword(s):  
Middle East ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Control And Prevention ◽  
The Common ◽  
Upper Respiratory ◽  
Polymerase Chain ◽  
Health Organization

Coronaviruses (CoVs) are a group of viral pathogens that infect mammals and birds. The presentation in humans is typically that of a mild upper respiratory tract infection, similar to the common cold. However, in recent years, dramatic attention has arisen for more lethal members of this viral family (e.g., severe acute respiratory syndrome [SARS-CoV], Middle East respiratory syndrome [MERS-CoV], and coronavirus disease 2019 [COVID-19]). The epidemiology, clinical presentation, diagnosis, and management of these viruses are discussed in this review. Importantly, new guideline tables from the Centers for Disease Control and Prevention, as well as the World Health Organization are provided at the conclusion of the review. This review contains 12 tables, 3 figure and 48 references. Keywords: Coronavirus, severe acute respiratory distress syndrome (SARS), Middle East respiratory syndrome (MERS), COVID-19, respiratory infection, antiviral, real-time polymerase chain reaction

Coronaviruses: HCoV, SARS-CoV, MERS-CoV, and COVID-19

2020 ◽  
Author(s):  
Michael G. Ison
Keyword(s):  
Middle East ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Viral Pathogens ◽  
Control And Prevention ◽  
The Common ◽  
Upper Respiratory ◽  
Polymerase Chain ◽  
Health Organization

Coronaviruses (CoVs) are a group of viral pathogens that infect mammals and birds. The presentation in humans is typically that of a mild upper respiratory tract infection, similar to the common cold. However, in recent years, dramatic attention has arisen for more lethal members of this viral family (e.g., severe acute respiratory syndrome [SARS-CoV], Middle East respiratory syndrome [MERS-CoV], and coronavirus disease 2019 [COVID-19]). The epidemiology, clinical presentation, diagnosis, and management of these viruses are discussed in this review. Importantly, new guideline tables from the Centers for Disease Control and Prevention, as well as the World Health Organization are provided at the conclusion of the review. This review contains 12 tables, 3 figure and 48 references. Keywords: Coronavirus, severe acute respiratory distress syndrome (SARS), Middle East respiratory syndrome (MERS), COVID-19, respiratory infection, antiviral, real-time polymerase chain reaction

scholarly journals The history and epidemiology of Middle East respiratory syndrome corona virus

2017 ◽  
Vol 12 ◽  
Author(s):  
Aisha M. Al-Osail ◽  
Marwan J. Al-Wazzah
Keyword(s):  
Middle East ◽  
Molecular Mechanisms ◽  
Middle Eastern ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Corona Virus ◽  
Control And Prevention ◽  
Novel Virus ◽  
Health Organization ◽  
Corona Viruses

Corona viruses cause common cold, and infections caused by corona viruses are generally self-resolving. During the last 4 years, corona viruses have become the most important viruses worldwide because of the occurrence of several recent deaths caused by corona viruses in Saudi Arabia. Spread of the infection occurred worldwide; however, most cases of mortality have occurred in the Middle East. Owing to the predominance of outbreaks in the Middle Eastern countries, the virus was renamed a Middle East respiratory syndrome corona virus (MERS-CoV) by the Corona virus Study Group. The Center for Diseases Control and Prevention and World Health Organization maintain a website that is updated frequently with new cases of MERS-CoV infection. In this review, we describe the history and epidemiology of this novel virus. Studies of the genetics and molecular mechanisms of this virus are expected to facilitate the development of vaccines in the future.

scholarly journals A database of geopositioned Middle East Respiratory Syndrome Coronavirus occurrences

2019 ◽  
Vol 6 (1) ◽  
Author(s):  
Rebecca E. Ramshaw ◽  
Ian D. Letourneau ◽  
Amy Y. Hong ◽  
Julia Hon ◽  
Julia D. Morgan ◽  
...  
Keyword(s):  
Middle East ◽  
Literature Search ◽  
Web Of Science ◽  
Contextual Information ◽  
Middle East Respiratory Syndrome ◽  
World Health ◽  
Exclusion Criteria ◽  
Information Index ◽  
Health Organization ◽  
Organization Research

AbstractAs a World Health Organization Research and Development Blueprint priority pathogen, there is a need to better understand the geographic distribution of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and its potential to infect mammals and humans. This database documents cases of MERS-CoV globally, with specific attention paid to zoonotic transmission. An initial literature search was conducted in PubMed, Web of Science, and Scopus; after screening articles according to the inclusion/exclusion criteria, a total of 208 sources were selected for extraction and geo-positioning. Each MERS-CoV occurrence was assigned one of the following classifications based upon published contextual information: index, unspecified, secondary, mammal, environmental, or imported. In total, this database is comprised of 861 unique geo-positioned MERS-CoV occurrences. The purpose of this article is to share a collated MERS-CoV database and extraction protocol that can be utilized in future mapping efforts for both MERS-CoV and other infectious diseases. More broadly, it may also provide useful data for the development of targeted MERS-CoV surveillance, which would prove invaluable in preventing future zoonotic spillover.

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