scholarly journals Molecular identification, expression and prognostic role of estrogen- and progesterone receptors in head and neck cancer

2007 ◽  
Author(s):  
J. Lukits ◽  
É. Remenár ◽  
E. Rásó ◽  
A. Ladányi ◽  
M. Kásler ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Molecular Identification ◽  
Neck Cancer ◽  
Progesterone Receptors ◽  
Prognostic Role ◽  
Estrogen And Progesterone Receptors

scholarly journals Circulating MicroRNAs as Prognostic Molecular Biomarkers in Human Head and Neck Cancer: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 2019 ◽  
pp. 1-12 ◽  
Author(s):  
Shree Ram Lamichhane ◽  
Thanuja Thachil ◽  
Harriet Gee ◽  
Natalie Milic
Keyword(s):  
Systematic Review ◽  
Overall Survival ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Cancer Patients ◽  
Neck Cancer ◽  
Meta Analysis ◽  
Prognostic Role ◽  
Circulating Micrornas

Background. Circulating microRNAs (miRNAs) are potential molecular biomarkers for cancer detection; however, little is known about their prognostic role in head and neck cancer. This current study is aimed at evaluating the role of novel miRNAs in the survival of head and neck cancer patients. Materials and Methods. We performed a systematic literature search using online databases for articles published between December 2006 and February 2019. A meta-analysis was conducted to assess the correlation between miRNA expressions and overall survival (OS) among the selected head and neck cancer studies. After multilevel screening by reviewers, meta-analysis was performed using hazard ratios (HR) and associated 95% confidence interval (CI) of survival to calculate a pooled effect size. Result. A total of 1577 patients across 13 studies were included in the literature review, with 18 miRNAs upregulated and 4 miRNAs downregulated predicting a poor overall survival. The forest plot generated using cumulated survival data resulted in a pooled HR value of 2.943 (95% CI: 2.394-3.618) indicating a strong association of dysregulated miRNA expression with a poor outcome. Only 2 miRNAs—low levels of miR-9 and high levels of miR-483-5p—were observed in two studies, both showing a significant association with overall cancer survival. Conclusion. To our knowledge, this is the first comprehensive systematic review and meta-analysis that examines the prognostic role of circulating miRNAs from blood in head and neck cancer patients. The combined effect estimates a HR across multiple studies and also supports the previous individual findings that an alteration in miRNA expression is highly associated with poor prognosis. This has the potential to use serum and/or plasma miRNAs as biomarkers and become novel tools for predicting the prognosis of head and neck cancer patients in the near future.

scholarly journals EP-1070: Prognostic role of FDG-PET performed before or during radiotherapy in head and neck cancer

2016 ◽  
Vol 119 ◽  
pp. S515
Author(s):  
M. Min ◽  
P. Lin ◽  
M. Lee ◽  
I. Ho Shon ◽  
M. Lin ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Fdg Pet ◽  
Prognostic Role

scholarly journals Prognostic Role of p16 in Non-oropharyngeal Head and Neck Cancer

2018 ◽  
Vol 100 (5) ◽  
pp. 1319
Author(s):  
A.K. Bryant ◽  
L. Vitzthum ◽  
K. Zakeri ◽  
H. Shen ◽  
J.D. Murphy ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Prognostic Role

scholarly journals Erratum to “Prognostic Role of Serum Amino Acids in Head and Neck Cancer”

2021 ◽  
Vol 2021 ◽  
pp. 1-1
Author(s):  
Gabriella Cadoni ◽  
Luca Giraldi ◽  
Carlo Chiarla ◽  
Jacopo Gervasoni ◽  
Silvia Persichilli ◽  
...  
Keyword(s):  
Amino Acids ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Prognostic Role ◽  
Serum Amino Acids

Prognostic role of internal jugular vein preservation in neck dissection for head and neck cancer

2013 ◽  
Vol 108 (8) ◽  
pp. 579-583 ◽  
Author(s):  
O. Gallo ◽  
R. Santoro ◽  
F.R. Fiorini ◽  
G. MecCariello ◽  
R.M. Laganà ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Dissection ◽  
Internal Jugular Vein ◽  
Neck Cancer ◽  
Jugular Vein ◽  
Prognostic Role

scholarly journals Prognostic Role of p16 in Nonoropharyngeal Head and Neck Cancer

2018 ◽  
Vol 110 (12) ◽  
pp. 1393-1399 ◽  
Author(s):  
Alex K Bryant ◽  
Elena J Sojourner ◽  
Lucas K Vitzthum ◽  
Kaveh Zakeri ◽  
Hanjie Shen ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Head And Neck ◽  
Neck Cancer ◽  
Prognostic Role

Evaluation of incidence, significance, and prognostic role of circulating tumor microemboli and transforming growth factor-β receptor I in head and neck cancer

Head & Neck ◽  
2017 ◽  
Vol 39 (11) ◽  
pp. 2283-2292 ◽  
Author(s):  
Marcello Ferretti Fanelli ◽  
Thiago Bueno Oliveira ◽  
Alexcia Camila Braun ◽  
Marcelo Corassa ◽  
Emne Ali Abdallah ◽  
...  
Keyword(s):  
Head And Neck Cancer ◽  
Growth Factor ◽  
Head And Neck ◽  
Neck Cancer ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Prognostic Role ◽  
Β Receptor ◽  
Circulating Tumor Microemboli

scholarly journals Can Bioelectrical Impedance Analysis and BMI Be a Prognostic Tool in Head and Neck Cancer Patients? A Review of the Evidence

Cancers ◽  
2020 ◽  
Vol 12 (3) ◽  
pp. 557 ◽  
Author(s):  
Maria Mantzorou ◽  
Maria Tolia ◽  
Antigoni Poultsidi ◽  
Eleni Pavlidou ◽  
Sousana K. Papadopoulou ◽  
...  
Keyword(s):  
Weight Loss ◽  
Head And Neck Cancer ◽  
Electrical Properties ◽  
Nutritional Status ◽  
Head And Neck ◽  
Disease Progression ◽  
Neck Cancer ◽  
Prognostic Role ◽  
The Impact

Background: Malnutrition can significantly affect disease progression and patient survival. The efficiency of weight loss and bioimpedance analysis (BIA)-derived measures in the evaluation of malnutrition, and disease progression and prognosis in patients with head and neck cancer (HNC) are an important area of research. Method: The PubMed database was thoroughly searched, using relative keywords in order to identify clinical trials that investigated the role of BIA-derived measures and weight loss on the disease progression and prognosis of patients with HNC. Twenty-seven studies met the criteria. More specifically, six studies examined the prognostic role of the tissue electrical properties in HNC patients; five examined the role of the tissue electrical properties on identifying malnutrition; four studies looked at the changes in the tissue electrical properties of HNC patients; and 12 examined the prognostic role of weight loss on survival and/or treatment outcomes. Results: Several studies have investigated the role of nutritional status tools on prognosis in HNC patients. Current studies investigating the potential of BIA-derived raw data have shown that phase angle (PA) and capacitance of the cell membrane may be considered prognostic factors of survival. Weight loss may be a prognostic factor for treatment toxicity and survival, despite some conflicting evidence. Conclusions: Further studies are recommended to clarify the role of BIA-derived measures on patients’ nutritional status and the impact of PA on clinical outcomes as well as the prognostic role of weight loss.

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