scholarly journals Phosphorylated STAT3 expression linked to SOCS3 methylation is associated with proliferative ability of gastric mucosa in patients with early gastric cancer

Author(s):  
Hirokazu Fukui ◽  
Jiro Watari ◽  
Xinxing Zhang ◽  
Ying Ran ◽  
Toshihiko Tomita ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Tadashi Miike ◽  
Shojiro Yamamoto ◽  
Yoshifumi Miyata ◽  
Tomoya Hirata ◽  
Yuko Noda ◽  
...  

Background and Aim. It is difficult to master the skill of discriminating gastric adenoma from early gastric cancer by conventional endoscopy or magnifying endoscopy combined with narrow-band imaging, because the colors and morphologies of these neoplasms are occasionally similar. We focused on the surrounding gastric mucosa findings in order to determine how to discriminate between early gastric cancer and gastric adenoma by analyzing the characteristics of the gastric background mucosa.Methods. We retrospectively examined 146 patients who underwent endoscopic submucosal dissection for gastric neoplasm between October 2009 and January 2015. The boundary of atrophic gastritis was classified endoscopically according to the Kimura-Takemoto classification system. Of 146 lesions, 63 early gastric cancers and 21 gastric adenomas were ultimately evaluated and assessed.Results. Almost all gastric adenomas were accompanied by open-type gastritis, whereas 47 and 16 early gastric cancers were accompanied by open-type and closed-type gastritis, respectively (p= 0.037).Conclusions. The evaluation of the boundary of atrophic gastritis associated with gastric neoplasms appears to be useful for discrimination between early gastric cancer and gastric adenoma. When gastric neoplasm is present in the context of surrounding localized gastric atrophy, gastric cancer is probable but not certain.


2011 ◽  
Vol 80 (Suppl 1) ◽  
pp. S6 ◽  
Author(s):  
Dae Hoon Kim ◽  
Kyoung Mee Kim ◽  
Seung Jong Oh ◽  
Jeong A Oh ◽  
Min Gew Choi ◽  
...  

JGH Open ◽  
2020 ◽  
Author(s):  
Narihiro Shibukawa ◽  
Shohei Ouchi ◽  
Shuji Wakamatsu ◽  
Yuhei Wakahara ◽  
Akira Kaneko

2020 ◽  
Vol 11 ◽  
Author(s):  
Lili Wang ◽  
Yongning Xin ◽  
Jianhua Zhou ◽  
Zibin Tian ◽  
Chenguang Liu ◽  
...  

1998 ◽  
Vol 68 (9) ◽  
pp. 369-374
Author(s):  
Naoko Nakamura ◽  
Takuya Hayashi ◽  
Tsunenori Arai ◽  
Shigeki Tokonabe ◽  
Harumi Itoh ◽  
...  

2021 ◽  
Vol 10 (16) ◽  
pp. 3649
Author(s):  
Shinya Matsumura ◽  
Osamu Dohi ◽  
Nobuhisa Yamada ◽  
Akihito Harusato ◽  
Takeshi Yasuda ◽  
...  

The visibility and diagnostic accuracy of early gastric cancer (EGC) after Helicobacter pylori (HP) eradication have been reported to improve using image-enhanced endoscopy (IEE) compared with white light imaging (WLI). The present study clarified the appropriate IEE for the detection and diagnosis of EGC in clinical settings. This prospective and cross-sectional study evaluated the visibility of EGC and endoscopic findings of gastric mucosa after successful HP eradication (n = 31) using videos with WLI and IEE. Three endoscopists evaluated high-definition videos in a randomized order. The mean visibility scores (MVSs) on linked color imaging (LCI) for atrophic border, intestinal metaplasia, map-like redness, and EGC were the highest among each modality (3.87 ± 0.34, 3.82 ± 0.49, 3.87 ± 0.50, and 3.35 ± 0.92, respectively). The MVSs with blue laser imaging (BLI) were highest for magnifying view of the demarcation line (DL), microsurface pattern (MSP), and microvascular pattern (MVP) for EGC (3.77 ± 0.49, 3.94 ± 0.25, and 3.92 ± 0.34, respectively). LCI had the highest visibility among findings of gastric mucosa and EGC after HP eradication, and BLI had the highest visibility of MVP, MSP, and DL in magnifying observation. These results suggest that LCI observation in the entire stomach and further magnifying BLI are the best methods for detecting and diagnosing EGCs after HP eradication, respectively.


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