Cardiac Involvement of Major Thalassemia and Evaluation of Total Serum Creatine Kinase and Creatine Kinase-MB Isoenzyme and Cardiac TroponinI in These Patients

2008 ◽  
Vol 11 (7) ◽  
pp. 1059-1062 ◽  
Author(s):  
K. Sakha ◽  
M. Samadi ◽  
A. Rezamand
Keyword(s):  
Creatine Kinase ◽  
Cardiac Involvement ◽  
Serum Creatine Kinase ◽  
Total Serum ◽  
Creatine Kinase Mb

Total Creatine Kinase and Isoenzyme Fractions in Chronic Dialysis Patients

1987 ◽  
Vol 10 (2) ◽  
pp. 72-76 ◽  
Author(s):  
S.M. Lal ◽  
K.D. Nolph ◽  
H. Hain ◽  
H.L. Moore ◽  
R. Khanna ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Peritoneal Dialysis ◽  
Continuous Ambulatory Peritoneal Dialysis ◽  
Serum Creatine Kinase ◽  
Chronic Dialysis ◽  
Maintenance Hemodialysis ◽  
Total Serum ◽  
Dialysis Patients ◽  
Creatine Kinase Mb ◽  
Total Creatine

We measured total serum creatine kinase (CK) and serum creatine kinase MB fraction (CK-MB) in 53 patients on continuous ambulatory peritoneal dialysis (CAPD) and 52 patients on maintenance hemodialysis (HD), using Scalva UV methodology for CK and electrophoresis for CK-MB. Seven of the 53 CAPD patients (13%) had an elevated total CK, and only one of these 7 patients had an elevated CK-MB > 5%. In contrast 22 HD patients (42%) had increased total CK values, and 6 of these 22 HD patients (27%) showed elevated CK-MB isoenzyme > 5%. For each sex, blacks had higher mean CK values than whites. Twenty-one out of the 43 HD patients who received intramuscular injections had elevated total CK values and 6 of these 21 patients had elevated CK-MB isoenzyme independent of the timing of injection. The increased frequency of higher total CK values in HD patients appears to be related to race and androgen administration. The modest elevations in CK-MB fraction (5 to 8%) in these patients require careful interpretation.

Total serum creatine kinase and isozyme concentrations in the owl monkey

1991 ◽  
Vol 20 (6) ◽  
pp. 290-294
Author(s):  
R.E. Weller ◽  
R.L. Buschbom ◽  
S.L. Martell ◽  
J.F. Baer ◽  
C.A. Málaga ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Serum Creatine Kinase ◽  
Total Serum ◽  
Owl Monkey

ASSOCIATION OF SERUM LACTATE LEVELS WITH CREATINE KINASE – MB AND LACTATE DEHYDROGENASE IN PATIENTS WITH MYOCARDIAL INFARCTION

2021 ◽  
pp. 73-75
Author(s):  
Mallaiyan Manonmani ◽  
Meiyappan Kavitha
Keyword(s):  
Myocardial Infarction ◽  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Serum Lactate ◽  
Serum Creatine Kinase ◽  
Hemodynamic Management ◽  
Diagnosis And Prognosis ◽  
Creatine Kinase Mb ◽  
Enzymatic Markers ◽  
Lactate Levels

Objectives: Myocardial infarction is the most common form of coronary heart disease, the commonest cause of worldwide mortality. The present biochemical markers take atleast 6 hours for elevation following an episode of myocardial infarction. There is a need for sensitive marker for early diagnosis and prognosis. Lactate, the end product of anaerobic glycolysis is found to be elevated in many critical illnesses. Thus the study was undertaken to assess the levels of serum lactate in patients with myocardial infarction and to correlate it with the frequently used enzymatic markers for the diagnosis of myocardial infarction, i.e creatine kinase – MB and lactate dehydrogenase Methods: Fifty age and sex matched controls and fty cases of myocardial infarction were included in the study. Serum creatine kinase – MB, lactate dehydrogenase and lactate were estimated in these subjects. Results:The serum lactate levels were signicantly higher among cases when compared to controls. The serum lactate levels positively correlated with serum creatine kinase – MB among cases but not with lactate dehydrogenase. Conclusions: We conclude that serum lactate is altered in patients with myocardial infarction and may be considered as a prognostic risk factor in these patients. Further studies are needed to nd the cut-off value of serum lactate for assistance in the hemodynamic management of these patients.

Serum Enzymes and Isoenzymes after Surgery

1977 ◽  
Vol 14 (1-6) ◽  
pp. 294-296 ◽  
Author(s):  
J. Krafft ◽  
R. Fink ◽  
S. B. Rosalki
Keyword(s):  
Myocardial Infarction ◽  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Clinical Evidence ◽  
Serum Creatine Kinase ◽  
Serum Enzymes ◽  
Aspartate Transaminase ◽  
Rare Association ◽  
Creatine Kinase Mb

Serum creatine kinase, aspartate transaminase, and hydroxybutyrate dehydrogenase activities were abnormal in 76, 50, and 28% respectively of 50 patients studied within 26 hours of surgery. No patient showed clinical evidence of myocardial infarction. Creatine kinase MB isoenzyme elevation, and lactate dehydrogenase LD1 activity greater than LD2 (LD1 > LD2) were infrequent (6 and 10% respectively). No patient showed the combination of transient MB isoenzyme elevation and LD1 > LD2, although their rare association without infarction after surgery is to be anticipated.

Serum creatine kinase-MB and lactate dehydrogenase-1 isoenzyme activities in piglets with encephalomyocarditis virus

1997 ◽  
Vol 140 (24) ◽  
pp. 628-629 ◽  
Author(s):  
C. Billinis ◽  
A. Koutinas ◽  
E. Paschaleri-Papadopoulou ◽  
O. Papadopoulos
Keyword(s):  
Creatine Kinase ◽  
Lactate Dehydrogenase ◽  
Serum Creatine Kinase ◽  
Encephalomyocarditis Virus ◽  
Creatine Kinase Mb

scholarly journals Influence of Gender on Total Serum Creatine Kinase and Creatine Kinase-Mb Levels of Nigerian Hypertensives

2021 ◽  
Vol 6 (2) ◽  
pp. 1436-1439
Author(s):  
Henry Afamuefuna Efobi ◽  
Iya Eze Bassey
Keyword(s):  
Blood Pressure ◽  
Body Mass Index ◽  
Creatine Kinase ◽  
Body Mass ◽  
The Body ◽  
Total Serum ◽  
Creatine Kinase Mb ◽  
Normotensive Subjects ◽  
Total Creatine ◽  
Gender Specific

Introduction: Hypertension is a long-term medical condition which when not detected and managed properly and on time often results to complications leading to disabilities and mortality. Gender has been known to affect the interpretation of some variables necessitating the need for gender-specific ranges. Objectives:This study evaluated total creatine kinase (CK) and creatine kinase-MB (CK-MB) isoenzyme activities of hypertensive subjects in Calabar, Nigeria and to assess if gender has influence on the activities of these enzymes. Methodology:One hundred and two participants were consecutively enrolled in this case control study. Serum total serum CK and CK-MB activity were evaluated in fifty one hypertensive and 51 normotensive subjects. The total CK levels were assessed using a spectrophotometric method while immunoinhibition method was used to determine the activity of CK-MB. Data was analyzed using Student’s t-test and Pearson’s correlation. Statistical significance was set at p<0.05. Results:The total creatine kinase activities of the hypertensives did not differ significantly from those of the normotensive controls (p = 0.428) while the serum CK-MB activities of the hypertensive subjects were significantly higher than those of the normotensive controls (p=0.000). The body mass index of the hypertensives was significantly higher than those of the normotensive subjects (p=0.030). Gender had no effect on the blood pressure, body mass index and levels of CK and CK-MB (p>0.05). There was also no significant correlation (p>0.05) between blood pressure, body mass index and the levels of CK and CK-MB. Conclusion:CK-MB activities were significantly higher in hypertensive subjects compared to normotensive controls. There were no gender specific differences in the CK-MB levels of male and female hypertensives. This cardiac marker should be included in the routine assessment of hypertensives and gender-specific considerations may not be necessary in the interpretation of the data.

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