The Haemolytic Changes During Progression of Pre-Diabetes to Type 2 Diabetes in a High-Fat High-Carbohydrate Diet-Induced Pre-Diabetic Rat Model

2021 ◽  
Vol 20 (2) ◽  
pp. 55-63
Author(s):  
N.C. Mzimela ◽  
P.S. Ngubane ◽  
A. Khathi
Keyword(s):  
Type 2 Diabetes ◽  
Rat Model ◽  
High Carbohydrate Diet ◽  
Diabetic Rat ◽  
High Fat ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Diabetic Rat Model

scholarly journals Long-Term Effects of a Very Low Carbohydrate Compared With a High Carbohydrate Diet on Renal Function in Individuals With Type 2 Diabetes

Medicine ◽  
2015 ◽  
Vol 94 (47) ◽  
pp. e2181 ◽  
Author(s):  
Jeannie Tay ◽  
Campbell H. Thompson ◽  
Natalie D. Luscombe-Marsh ◽  
Manny Noakes ◽  
Jonathan D. Buckley ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Renal Function ◽  
High Carbohydrate Diet ◽  
Long Term Effects ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Low Carbohydrate

Antidiabetic and Antioxidant Effect ofSemecarpus anacardiumLinn. Nut Milk Extract in a High-Fat Diet STZ-Induced Type 2 Diabetic Rat Model

2011 ◽  
Vol 9 (1) ◽  
pp. 19-33 ◽  
Author(s):  
Haseena Banu Hedayathullah Khan ◽  
Kaladevi Siddhi Vinayagam ◽  
Ashwini Sekar ◽  
Shanthi Palanivelu ◽  
Sachdanandam Panchanadham
Keyword(s):  
Rat Model ◽  
High Fat Diet ◽  
Antioxidant Effect ◽  
Diabetic Rat ◽  
High Fat ◽  
Diabetic Rat Model ◽  
Type 2 Diabetic

scholarly journals Preventative Effect ofZingiber officinaleon Insulin Resistance in a High-Fat High-Carbohydrate Diet-Fed Rat Model and its Mechanism of Action

2014 ◽  
Vol 115 (2) ◽  
pp. 209-215 ◽  
Author(s):  
Yiming Li ◽  
Van H. Tran ◽  
Bhavani P. Kota ◽  
Srinivas Nammi ◽  
Colin C. Duke ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Mechanism Of Action ◽  
Rat Model ◽  
High Carbohydrate Diet ◽  
High Fat ◽  
Carbohydrate Diet ◽  
High Carbohydrate

Skeletal characters in type 2 diabetic rat model induced by high fat diet and low dose streptozotocin

Bone ◽  
2008 ◽  
Vol 42 ◽  
pp. S66
Author(s):  
Liping Zhang ◽  
Haiqin Rong ◽  
Hong Ji ◽  
Yaping Liu ◽  
Dong Wang
Keyword(s):  
Rat Model ◽  
High Fat Diet ◽  
Low Dose ◽  
Diabetic Rat ◽  
High Fat ◽  
Diabetic Rat Model ◽  
Type 2 Diabetic

scholarly journals Antihyperglycemic effect of rice husk derived xylooligosaccharides in high‐fat diet and low‐dose streptozotocin‐induced type 2 diabetic rat model

2019 ◽  
Vol 8 (1) ◽  
pp. 428-444 ◽  
Author(s):  
Nuntawat Khat‐udomkiri ◽  
Parichart Toejing ◽  
Sasithorn Sirilun ◽  
Chaiyavat Chaiyasut ◽  
Narissara Lailerd
Keyword(s):  
Rice Husk ◽  
Rat Model ◽  
High Fat Diet ◽  
Low Dose ◽  
Diabetic Rat ◽  
High Fat ◽  
Antihyperglycemic Effect ◽  
Diabetic Rat Model ◽  
Type 2 Diabetic

Anti-diabetic effect of Semecarpus anacardium Linn nut milk extract in a high fat diet STZ-induced type 2 diabetic rat model

2011 ◽  
Vol 21 (6) ◽  
pp. 1395-1400 ◽  
Author(s):  
Haseena Banu Hedayathullah Khan ◽  
Kaladevi Siddhi Vinayagam ◽  
Shanthi Palanivelu ◽  
Sachdanandam Panchanatham
Keyword(s):  
Rat Model ◽  
High Fat Diet ◽  
Diabetic Rat ◽  
High Fat ◽  
Semecarpus Anacardium ◽  
Diabetic Rat Model ◽  
Type 2 Diabetic

The effect of high carbohydrate diet on glucose tolerance in patients with type 2 diabetes mellitus

2002 ◽  
Vol 57 (3) ◽  
pp. 163-170 ◽  
Author(s):  
Nobuyuki Komiyama ◽  
Takashi Kaneko ◽  
Akio Sato ◽  
Wataru Sato ◽  
Kaoru Asami ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glucose Tolerance ◽  
High Carbohydrate Diet ◽  
Carbohydrate Diet ◽  
High Carbohydrate

scholarly journals Comparative Liver Transcriptome Analysis on Kunming mice with Streptozotocin and Natural Food Induced Type 2 Diabetes Mellitus

2021 ◽  
Author(s):  
YANJUN WU ◽  
XIANGXING ZHU ◽  
Arome Solomon Odiba ◽  
Zisheng LIN ◽  
JIANCONG WEN ◽  
...  
Keyword(s):  
Diabetic Animal ◽  
High Carbohydrate Diet ◽  
Natural Food ◽  
Standard Diet ◽  
High Fat ◽  
Carbohydrate Diet ◽  
Kegg Pathways ◽  
High Carbohydrate ◽  
Liver Transcriptome

Abstract Background: Streptozotocin is a classic drug used to induce diabetic animal models. Objective: The aim of this study is to investigate the liver transcriptome of diabetic Kunming mice induced by streptozotocin (STZ) or Non-STZ. Methods: Forty male mice were randomly assigned into 4 groups, namely Control (Ctr, standard diet), mHH (high fat and high carbohydrate diet), mHS (high fat and high carbohydrate diet for 4 weeks followed by 60 mg/kg STZ for 3 consecutive days) and mSH (60 mg/kg STZ for 3 consecutive days and then fed with high fat and high carbohydrate diet for 12 weeks). All mice injected with STZ were identified as diabetes despite the sequential feeding of high fat and high carbohydrate diet. Results: Only 7 of 13 mice in mHH group met the diagnostic criteria for diabetes. The FBG of mHH, mHS, mSH and Ctrl groups were 13.27 ± 1.14, 15.01 ± 2.59, 15.95 ± 4.38 and 6.28 ± 0.33 mmol/L at 12th week, respectively. Compared with mHH group, the transcriptions of 85 genes were elevated in liver of mHS mice while 21 genes were down-regulated, and 97 genes were shown to be up-regulated in mSH group while 35 genes were decreased. Total 43 co-expressed genes were identified in mHSvsmHH and mSHvsmHH groups. GO (Gene Ontology) and KEGG (Kyoto Encyclopedia of Genes and Genomes) analyses showed that there were 2 corporate GO terms and 2 KEGG pathways significantly annotated in STZ-treated groups. Both the GO term and pathway were related to the metabolism mediated by p53. Conclusion: High fat and high carbohydrate diet combined with low dose of STZ can effectively induce diabetic models in Kunming mice despite the abnormal expressions of genes in the liver. The differentially expressed genes were related to the metabolism mediated by p53.

High-monounsaturated fat, olive oil-rich diet has effects similar to a high-carbohydrate diet on fasting and postprandial state and metabolic profiles of patients with type 2 diabetes

Metabolism ◽  
2000 ◽  
Vol 49 (12) ◽  
pp. 1511-1517 ◽  
Author(s):  
Camino Rodrı́guez-Villar ◽  
José M. Manzanares ◽  
Elena Casals ◽  
Ana Pérez-Heras ◽  
Daniel Zambón ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Olive Oil ◽  
High Carbohydrate Diet ◽  
Metabolic Profiles ◽  
Monounsaturated Fat ◽  
Carbohydrate Diet ◽  
High Carbohydrate ◽  
Postprandial State
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