Combined Hamartoma of the Retina and Retinal Pigment Epithelium with Full Thickness Retinal Hole and without Retinoschisis

The authors report a case of a male patient affected by macular hole. In particular, a hyperreflective tissue was found on optical coherence tomography (OCT) examination in macular region, just above the retinal pigment epithelium (RPE). OCT angiography (OCTA) did not show the presence of vascular tissue, thus the hyperreflective material was ascribed to primary gliotic tissue. This case highlights the ability for Müller cells placed near macular holes to migrate up to the RPE and to produce gliotic tissue.

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Simultaneous retinal pigment epithelium tear and lamellar macular hole evolving to a full-thickness macular hole after intravitreal injection

Journal Français d Ophtalmologie ◽

10.1016/j.jfo.2019.11.010 ◽

2020 ◽

Vol 43 (7) ◽

pp. e237-e239 ◽

Cited By ~ 1

Author(s):

A. Moll-Udina ◽

S. Alforja-Castiella ◽

J.P. Figueroa-Vercellino ◽

A. Alé-Chilet ◽

R.P. Casaroli-Marano

Keyword(s):

Retinal Pigment Epithelium ◽

Intravitreal Injection ◽

Macular Hole ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Lamellar Macular Hole ◽

Full Thickness ◽

Full Thickness Macular Hole

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Full Thickness Retinal Hole Formation after Nd:YAG Laser Hyaloidotomy in a Case with Valsalva Retinopathy

Case Reports in Ophthalmological Medicine ◽

10.1155/2018/2874908 ◽

2018 ◽

Vol 2018 ◽

pp. 1-4

Author(s):

Yasin Sakir Goker ◽

Kemal Tekin ◽

Cemile Ucgul Atilgan ◽

Pinar Kosekahya ◽

Pelin Yilmazbas

Keyword(s):

Nd:Yag Laser ◽

Pigment Epithelium ◽

Care Center ◽

Retinal Pigment ◽

Full Thickness ◽

Hole Formation ◽

Inferior Margin ◽

Valsalva Retinopathy ◽

Vascular Arcade ◽

Retinal Hole

A 27-year-old male was presented with a sudden onset of visual loss in his right eye. A secondary care center referred the patient with fundus photographs which were screened 4 days before and after the Nd: YAG laser hyaloidotomy treatment. Snellen acuity was 10/10 in both eyes. Fundus examinations revealed a retinal pigment epithelium (RPE) alteration at the margin of the inferior temporal arterial vascular arcade in the right eye and resolved preretinal and subretinal hemorrhages were seen in the macula. A diagnosis of Valsalva retinopathy was made based on the history and the treatment photographs of Nd:YAG laser hyaloidotomy. At 1st month examination all hemorrhages were resolved but RPE alterations were still at the margin of the inferior temporal arterial vascular arcade. The optical coherence tomography angiography (OCTA) images revealed 2 lesions. On en face OCT angiogram of OCTA full thickness retinal hole formation and ellipsoid zone damage at the superior and inferior margin of the inferior temporal arterial vascular arcade were seen. Superficial vascular plexus was also damaged at that region. The projection of the evacuation of blood from subhyaloid space and the full thickness retinal hole formation were the same, indicating that the partial and full thickness retinal holes were created by the laser treatment.

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CONGENITAL SIMPLE HAMARTOMA OF THE RETINAL PIGMENT EPITHELIUM WITH A FULL-THICKNESS MACULAR HOLE

Retinal Cases & Brief Reports ◽

10.1097/icb.0b013e318158de64 ◽

2009 ◽

Vol 3 (1) ◽

pp. 80-82 ◽

Cited By ~ 1

Author(s):

Ann Van de Moere ◽

J Ben Clark

Keyword(s):

Retinal Pigment Epithelium ◽

Macular Hole ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Full Thickness ◽

Full Thickness Macular Hole

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High-voltage electron microscopy of subretinal scar formation

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s0424820100122836 ◽

1992 ◽

Vol 50 (1) ◽

pp. 486-487

Author(s):

G.E. Korte ◽

M. Marko ◽

G. Hageman

Keyword(s):

Electron Microscopy ◽

Monoclonal Antibody ◽

Retinal Pigment Epithelium ◽

Glial Cells ◽

High Voltage ◽

Pigment Epithelium ◽

Retinal Pigment ◽

Sodium Iodate ◽

High Voltage Electron Microscopy ◽

Voltage Electron

Sodium iodate iv. damages the retinal pigment epithelium (RPE) in rabbits. Where RPE does not regenerate (e.g., 1,2) Muller glial cells (MC) forma subretinal scar that replaces RPE. The MC response was studied by HVEM in 3D computer reconstructions of serial thick sections, made using the STEREC0N program (3), and the HVEM at the NYS Dept. of Health in Albany, NY. Tissue was processed for HVEM or immunofluorescence localization of a monoclonal antibody recognizing MG microvilli (4).

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