scholarly journals In Vitro Study of Dentinal Tubule Occlusion with Sol-gel DP-bioglass for Treatment of Dentin Hypersensitivity

2007 ◽  
Vol 26 (1) ◽  
pp. 52-61 ◽  
Author(s):  
Bor-Shiunn LEE ◽  
Shu-Han KANG ◽  
Yin-Lin WANG ◽  
Feng-Huei LIN ◽  
Chun-Pin LIN
2010 ◽  
Vol 38 (5) ◽  
pp. 400-410 ◽  
Author(s):  
Zhejun Wang ◽  
Yue Sa ◽  
Salvatore Sauro ◽  
Hao Chen ◽  
Wenzhong Xing ◽  
...  

Nanomaterials ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 3150
Author(s):  
Manuel Toledano-Osorio ◽  
Raquel Osorio ◽  
Estrella Osorio ◽  
Antonio L. Medina-Castillo ◽  
Manuel Toledano

Tubule occlusion and remineralization are considered the two main goals of dentin hypersensitivity treatment. The objective is to assess the ability of dentifrices containing zinc-doped polymeric nanoparticles (NPs) to enduringly occlude the dentinal tubules, reinforcing dentin’s mechanical properties. Fifteen dentin surfaces were acid-treated for dentinal tubule exposure and brushed with (1) distilled water, or with experimental pastes containing (2) 1% of zinc-doped NPs, (3) 5% of zinc-doped NPs, (4) 10% of zinc-doped NPs or (5) Sensodyne®. Topographical and nanomechanical analyses were performed on treated dentin surfaces and after a citric acid challenge. ANOVA and Student–Newman–Keuls tests were used (p < 0.05). The main results indicate that all pastes produced tubule occlusion (100%) and reinforced mechanical properties of intertubular dentin (complex modulus was above 75 GPa). After the citric acid challenge, only those pastes containing zinc-doped NPs were able to maintain tubular occlusion, as specimens treated with Sensodyne® have around 30% of tubules opened. Mechanical properties were maintained for dentin treated with Zn-doped NPs, but in the case of specimens treated with Sensodyne®, complex modulus values were reduced below 50 GPa. It may be concluded that zinc-doped NPs at the lowest tested concentration produced acid-resistant tubular occlusion and increased the mechanical properties of dentin.


1993 ◽  
Vol 64 (11) ◽  
pp. 1045-1051 ◽  
Author(s):  
William E. Dragolich ◽  
David H. Pashley ◽  
William A. Brennan ◽  
Robert B. O'Neal ◽  
Jack A. Horner ◽  
...  

2021 ◽  
Vol 29 ◽  
Author(s):  
Hongmin ZHUANG ◽  
Yuee LIANG ◽  
Shaowen XIANG ◽  
Huanying LI ◽  
Xingzhu DAI ◽  
...  

2021 ◽  
Vol 71 (11) ◽  
pp. 2604-2610
Author(s):  
Hashmat Gul ◽  
Muhammad Asad Ghaffar ◽  
Muhammad Kaleem ◽  
Abdul Samad Khan

Objective: This study reviews different modes of application of hydroxyapatite for treatment of dentin hypersensitivity via dentinal tubule occlusion. Methods: Literature search was performed using keywords, “hydroxyapatite and dentin hypersensitivity, hydroxyapatite and dentinal tubule occlusion, hydroxyapatite and dentin permeability, dentinal tubule occlusion” on Pubmed, Science Direct and Web of Science, which involved the results of previous 10 years (2009-2018). After screening, 16 studies were included in systematic review. Results: The results of in-vitro studies showed that application of hydroxyapatite caused dentinal tubule occlusion leading to reduction in dentin permeability and reduction in dentin hypersensitivity. Conclusion: Hydroxyapatite has the potential to reduce dentin hypersensitivity via dentinal tubule occlusion within 2-8 weeks. Keywords: Dentin hypersensitivity, Hydroxyapatite, Dentinal tubule occlusion. Continuous...


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