Synergistic Antibacterial Effect and Antibacterial Action Mode of Chitosan-Ferulic Acid Conjugate against Methicillin-Resistant Staphylococcus aureus

2016 ◽  
Vol 26 (4) ◽  
pp. 784-789 ◽  
Author(s):  
Sung-Hwan Eom ◽  
Shin-Kook Kang ◽  
Dae-Sung Lee ◽  
Jeong-In Myeong ◽  
Jinhwan Lee ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Ferulic Acid ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antibacterial Effect ◽  
Antibacterial Action ◽  
Methicillin Resistant ◽  
Action Mode ◽  
Acid Conjugate

scholarly journals Antibacterial Alkaloids from Chelidonium Majus Linn (Papaveraceae) Against Clinical Isolates of Methicillin-Resistant Staphylococcus Aureus

2009 ◽  
Vol 11 (4) ◽  
pp. 90 ◽  
Author(s):  
Guo Ying Zuo ◽  
Fan Yan Meng ◽  
Xiao Yan Hao ◽  
Yun Ling Zhang ◽  
Gen Chun Wang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibacterial Agents ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antibacterial Effect ◽  
Dilution Method ◽  
Chelidonium Majus ◽  
Methicillin Resistant ◽  
Aerial Parts ◽  
Bioassay Guided Fractionation ◽  
Mrsa Strains

Purpose. This study describes the antibacterial effect of extracts and compounds isolated from the aerial part of Chelidonium majus Linn. (Papaveraceae) acting against clinical strains of methicillin-resistant Staphylococcus aureus (MRSA). Methods. The activities were evaluated by using the macrobroth dilution method and reported as the MICs/MBCs. Results. Bioassay-guided fractionation of the most active extract from the aerial parts (EtOAc) led to the isolation of benzo[c]phenanthridine-type alkaloids 8-hydroxydihydrosanguinarine (hhS), 8-hydroxydihydrochelerythrine (hhC), which were potently active against MRSA strains. Conclusions. The selective antibacterial activity reported in this paper for 8-hydroxylated benzo[c]phenanthridine-type alkaloids isolated from C.majus opens the possibility that they could be helpful for the developing of new antibacterial agents for treating the infection of MRSA which has created nosocomial problem worldwide.

scholarly journals Antioxidant and inhibitory activity of Roselle Extract (Hibiscus sabdariffa L.) against Methicillin-Resistant Staphylococcus aureus (MRSA)

2021 ◽  
Vol 8 (1) ◽  
pp. 28
Author(s):  
Nuril Fikriyah ◽  
Isnaeni Isnaeni ◽  
Asri Darmawati
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antibacterial Effect ◽  
Antioxidant Effect ◽  
Diffusion Method ◽  
Tropical Region ◽  
Hibiscus Sabdariffa ◽  
Methicillin Resistant ◽  
Inhibition Concentration ◽  
Agar Media

Background: Hibiscus sabdariffa known as roselle, which belongs to the family Malvaceae, grows in sub-tropical and tropical region including Indonesia. Several studies have reported the benefits of roselle for health. Roselle extract has been shown to have antibacterial effect as a support for antibacterial therapy, especially for case of antibiotic resistance, and antioxidant effect which can neutralize free radicals. Purpose: The aim of this study was obtaining the minimum inhibitory concentration (MIC) and inhibition concentration (IC50) of roselle extract. Methods: Antibacterial effect of roselle extract against Methicillin-Resistant Staphylococcus aureus (MRSA) was tested in nutrient agar media using diffusion method. Antioxidant activity of roselle extract was performed by DPPH. The violet color of DPPH solutions that was reduced by roselle extract were measured using visible spectrophotometer at the wavelength of 516 nm. Result: The result of this study obtained the (MIC) and IC50 of roselle extract were 2,5% and 1251±202,32 ppm, respectively. Conclusion: It can be concluded that roselle extract have antibacterial effect against MRSA and antioxidant effect.

Synergistic antibacterial effect of curcumin against methicillin-resistant Staphylococcus aureus

Phytomedicine ◽  
2013 ◽  
Vol 20 (8-9) ◽  
pp. 714-718 ◽  
Author(s):  
Su-Hyun Mun ◽  
Dae-Ki Joung ◽  
Yong-Sik Kim ◽  
Ok-Hwa Kang ◽  
Sung-Bae Kim ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Antibacterial Effect ◽  
Methicillin Resistant
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