Bioactive Organic-Inorganic Hybrids Prepared from Poly(Vinyl Alcohol) via Modification with Metal Oxides and Calcium Salt

Organic polymers with ability of apatite formation in body environment are expected as novel bone substitutes having not only bone-bonding ability, i.e. bioactivity, but also mechanical performance analogous to natural bone. Several metal oxides have been found to be effective for the apatite deposition in body environment. In addition, release of calcium ions from the materials significantly enhances it. In this study, we attempted to synthesize bioactive organic-inorganic hybrids from Poly(vinyl alcohol) (PVA) by incorporation of various metal oxides and calcium salt. Silica and molybdenum oxides were selected as metal oxides. Ability of apatite formation on the hybrids was examined in vitro using simulated body fluid (SBF, Kokubo solution). Apatite deposition were observed to occur on the surfaces of PVA/silica and PVA/molybdenum oxide hybrids in SBF, when their compositions were appropriately controlled.

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Bioactive Organic-Inorganic Hybrids Prepared from Poly(Vinyl Alcohol) via Modification with Metal Oxides and Calcium Salt

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.309-311.1153 ◽

2006 ◽

Vol 309-311 ◽

pp. 1153-1156 ◽

Cited By ~ 3

Author(s):

Caihong You ◽

Toshiki Miyazaki ◽

Eiichi Ishida ◽

Masahiro Ashizuka ◽

Chikara Ohtsuki

Keyword(s):

Metal Oxides ◽

Titanium Oxide ◽

Vinyl Alcohol ◽

Calcium Salt ◽

Mechanical Performance ◽

Bone Substitutes ◽

Poly Vinyl Alcohol ◽

Apatite Formation ◽

Apatite Deposition

Organic polymers with ability of apatite formation in body environment are expected as novel bone substitutes having not only bone-bonding ability, i.e. bioactivity, but also mechanical performance analogous to natural bone. Several metal oxides have been found to be effective for the apatite deposition in body environment. In addition, release of calcium ions from the materials significantly enhances it. In this study, we attempted to synthesize bioactive organic-inorganic hybrids from poly(vinyl alcohol) (PVA) by incorporation of titanium oxide or zirconium oxide as well as calcium salt. Ability of apatite formation on the hybrids was examined in vitro using simulated body fluid (SBF, Kokubo solution). Apatite deposition was observed to occur on the surfaces of PVA/titanium oxide hybrids in SBF, when their compositions were appropriately controlled.

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Apatite Deposition on Organic-Inorganic Hybrids Synthesized from Poly(Vinyl Alcohol) and Various Metal Oxides

Bioceramics 17 - Key Engineering Materials ◽

10.4028/0-87849-961-x.469 ◽

2005 ◽

pp. 469-472 ◽

Cited By ~ 1

Author(s):

Caihong You ◽

Toshiki Miyazaki ◽

Eiichi Ishida ◽

Masahiro Ashizuka ◽

Chikara Ohtsuki ◽

...

Keyword(s):

Metal Oxides ◽

Vinyl Alcohol ◽

Poly Vinyl Alcohol ◽

Apatite Deposition

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Green hybrid nanocomposites from metal oxides, poly(vinyl alcohol) and poly(vinyl pyrrolidone)

Hybrid Polymer Composite Materials ◽

10.1016/b978-0-08-100791-4.00010-0 ◽

2017 ◽

pp. 263-289 ◽

Cited By ~ 1

Author(s):

Shadpour Mallakpour ◽

Vajiheh Behranvand

Keyword(s):

Metal Oxides ◽

Vinyl Alcohol ◽

Hybrid Nanocomposites ◽

Vinyl Pyrrolidone ◽

Poly Vinyl Alcohol ◽

Poly Vinyl Pyrrolidone

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Micro-injection molded, poly(vinyl alcohol)-calcium salt templates for precise customization of 3D hydrogel internal architecture

Acta Biomaterialia ◽

10.1016/j.actbio.2019.04.050 ◽

2019 ◽

Vol 95 ◽

pp. 258-268 ◽

Cited By ~ 5

Author(s):

Jason D. McNulty ◽

Carlos Marti-Figueroa ◽

Frank Seipel ◽

Joshua Z. Plantz ◽

Thomas Ellingham ◽

...

Keyword(s):

Vinyl Alcohol ◽

Calcium Salt ◽

Poly Vinyl Alcohol ◽

Injection Molded ◽

Internal Architecture

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Polymer assisted colloidal nanocrystal framework synthesis: sol-gel approach

Materials Research Express ◽

10.1088/2053-1591/ac3e26 ◽

2021 ◽

Author(s):

Buzuayehu Abebe

Keyword(s):

Image Analysis ◽

Metal Oxides ◽

Vinyl Alcohol ◽

Sol Gel ◽

Compositional Analysis ◽

Sem Analysis ◽

Poly Vinyl Alcohol ◽

Hrtem Image ◽

Xrd Pattern ◽

Hsab Theory

Abstract The porous colloidal nanocrystal framework material was synthesized by sol-gel assembly followed by a self-propagation procedure. The characteristics of the synthesized nanocrystal were confirmed by advanced instruments. From the DTG analysis, the poly (vinyl alcohol) was completely degraded at 400 °C. The XRD pattern and TEM image confirmed the nanoscale crystallite size of the material. BET and SEM analysis showed the mesoporous type pore size distribution. The predictable compositional analysis was confirmed from EDX, SAED, and XPS compositional analysis. Using the HSAB theory and HRTEM image analysis the formation of local heterojunction between metal oxides was approved.

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