Assessment on Performance-properties of Asymmetric Nanofiltration Membranes from Polyethersulfone/n-Methyl-2-pyrrolidone/water Blends with Poly(vinyl pyrrolidone) as Additive

In this study, the effect of poly(vinyl pyrrolidone) (PVP) additive on the fabrication of asymmetric nanofiltration (NF) membranes was investigated in terms of performance, structural details and key properties. On addition of PVP ranging from 2 to 10 wt% into the dope solution, the fabricated NF membranes exhibited significantly different in properties and improved performance. In particular, the membranes made from 2 wt% PVP had the highest water flux and salt rejection of about 3.61 × 10–6 m3/m2s and 44.49 %, respectively. Modeling results revealed that small amount of PVP (2–4 wt%) produced finer structural properties. Moreover, the key properties (rp, ∆x/Ak and ζ) of the fabricated NF membranes were found to be within the range of that of commercial NF membranes.

Synthesis of silver nanocomposite hydrogels based on Poly (acrylic acid) and Poly (vinyl pyrrolidone) grafted onto Salep biopolymer and its use in drug release

This study aimed to synthesize a silver nanocomposite hydrogel based on poly (acrylic acid) and poly (vinyl pyrrolidone) grafted onto salep biopolymer and its use in controlled drug release. Drug release is one of the medicine goals that have been happening in the different methods, such as injections, pills or sprays. The useful drug dose, has measured by the drug concentration in the blood system, in the specific time. Researches have shown, in above methods, at the first time there is a high concentration of drug in the blood and by passing the time, this concentration decreases, so for achieve the useful drug dose, more drug is needed which it usually causes the increasing of the drug side effects. Thus for preventing these side effects, controlled drug release is investigated in this research. To identify the synthesized hydrogel, Fourier transform infrared spectroscopy (FTIR, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and thermometric gravimetric analysis (TGA) were used. The results showed that the release of deferasirox from the silver nanocomposite hydrogel network is related to the pH of the environment. In addition, the biodegradability and biocompatibility of this system have led to its use in the pharmaceutical industry.