Chiral Recognition of L-Carnitine Using Surface Molecularly Imprinted Microspheres via RAFT Polymerization

2014 ◽  
Vol 884-885 ◽  
pp. 33-36 ◽  
Author(s):  
Lin Tong Hou ◽  
Jiao Jiao Chen ◽  
Hong Jun Fu ◽  
Xin Lei Fu
Keyword(s):  
Experimental Data ◽  
Chiral Recognition ◽  
Chain Transfer ◽  
Raft Polymerization ◽  
Isothermal Adsorption ◽  
Molecularly Imprinted ◽  
Reversible Addition ◽  
Ft Ir ◽  
Molecularly Imprinted Microspheres

A molecularly imprinted microsphere (MIPs) was prepared successfullyviasurface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization. Characterization of the obtained MIPs was achieved by FT-IR and TGA. The isothermal adsorption and chiral separation experiments of MIPs on L-Carnitine were investigated. Compared with non-imprinted microsphere (NMIPs) adsorbent, MIPs showed faster adsorption rate and stronger adsorption capacity for L-Carnitine. Equilibrium experimental data of MIPs fitted the Langmuir isotherm better. Furthermore, the MIPs also exhibited enantioselectivity for L-Carnitine through the resolution experiment.

scholarly journals Preparation and characterization of polyacrylate functionalized polythiophene films

2018 ◽  
Vol 175 ◽  
pp. 01007
Author(s):  
Yahui Lv ◽  
Fei Wu ◽  
Chengshuai Liu ◽  
Changzhong Liao ◽  
Yingheng Fei ◽  
...  
Keyword(s):  
Chain Transfer ◽  
Electrochemical Sensors ◽  
Raft Polymerization ◽  
Free Standing ◽  
Fluorescence Spectrophotometry ◽  
Electrochemical Reversibility ◽  
Reversible Addition ◽  
Ft Ir ◽  
Ft Ir Spectroscopy

This paper is based on the effect of precursors’ structure on the resultant electropolymers’ electrochemical and optical and thermal properties. The polyacrylate functionalized thiophene with a narrow polydispersity index (PDI) was synthesized by means of reversible addition-fragmentation chain transfer (RAFT) polymerization, and then the free-standing and conducting conjugated polyacrylate functionalized polythiophene (R-PTE-PAA) film was prepared through electropolymerization in CH2Cl2 with 50% BFEE (boron trifluoride diethyl etherate). For comparison, the polyacrylate functionalized polythiophene (PTE-PAA) was also prepared with the precursor of a broad PDI from conventional free radical polymerization. The prepared polymers were characterized by UV-vis, FT-IR spectroscopy, thermogravimetry, cyclic voltammetry, scanning electron microscopy and fluorescence spectrophotometry. The R-PTE-PAA film showed the excellent electrochemical behavior, good blue-light property and high thermal stability. Compared with PTE-PAA, the R-PTE-PAA film presented the better electrochemical reversibility and stability. The results obtained in the present study indicate that the R-PTE-PAA film would be important for applications in electrochromics, supercapacitors and electrochemical sensors.

Preparation and Characterization of PMMA-b-PDMAEMA/Polysulfone Composite Membranes by RAFT Polymerization and their Permeation Performance of Carbon Dioxide

2011 ◽  
Vol 284-286 ◽  
pp. 1717-1723 ◽  
Author(s):  
Jiang Nan Shen ◽  
Yun Fei Ye ◽  
Gan Ning Zeng ◽  
Jun Hong Qiu
Keyword(s):  
Chain Transfer ◽  
Raft Polymerization ◽  
Gel Permeation Chromatography ◽  
Composite Membranes ◽  
Reversible Addition ◽  
Composition And Structure ◽  
Gel Permeation ◽  
Ft Ir ◽  
Ft Ir Spectroscopy

PMMA-b-PDMAEMA/polysulfone composite membranes for CO2separation was prepared by reversible addition-fragmentation chain transfer (RAFT) polymerization techniques. The chemical composition and structure of the polymers were characterized by Fourier transform infrared (FT-IR) spectroscopy, nuclear magnetic resonance (NMR), and molecular weight and its distribution were measured by Gel permeation chromatography (GPC). CO2permeation performance of the PMMA-b-PDMAEMA/ polysulfone composite membranes was test. The results showed that the resulted composited membrane posses good permeation performance for CO2.

scholarly journals Nano-Assemblies from Amphiphilic PnBA-b-POEGA Copolymers as Drug Nanocarriers

Polymers ◽  
2021 ◽  
Vol 13 (7) ◽  
pp. 1164
Author(s):  
Angeliki Chroni ◽  
Thomas Mavromoustakos ◽  
Stergios Pispas
Keyword(s):  
Molecular Weight ◽  
Chain Transfer ◽  
Raft Polymerization ◽  
Polymeric Nanocarriers ◽  
Reversible Addition ◽  
2D Noesy ◽  
Drug Nanocarriers ◽  
Glycol Methyl Ether ◽  
Different Molecular Weight

The focus of this study is the development of highly stable losartan potassium (LSR) polymeric nanocarriers. Two novel amphiphilic poly(n-butyl acrylate)-block-poly(oligo(ethylene glycol) methyl ether acrylate) (PnBA-b-POEGA) copolymers with different molecular weight (Mw) of PnBA are synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization, followed by the encapsulation of LSR into both PnBA-b-POEGA micelles. Based on dynamic light scattering (DLS), the PnBA30-b-POEGA70 and PnBA27-b-POEGA73 (where the subscripts denote wt.% composition of the components) copolymers formed micelles of 10 nm and 24 nm in water. The LSR-loaded PnBA-b-POEGA nanocarriers presented increased size and greater mass nanostructures compared to empty micelles, implying the successful loading of LSR into the inner hydrophobic domains. A thorough NMR (nuclear magnetic resonance) characterization of the LSR-loaded PnBA-b-POEGA nanocarriers was conducted. Strong intermolecular interactions between the biphenyl ring and the butyl chain of LSR with the methylene signals of PnBA were evidenced by 2D-NOESY experiments. The highest hydrophobicity of the PnBA27-b-POEGA73 micelles contributed to an efficient encapsulation of LSR into the micelles exhibiting a greater value of %EE compared to PnBA30-b-POEGA70 + 50% LSR nanocarriers. Ultrasound release profiles of LSR signified that a great amount of the encapsulated LSR is strongly attached to both PnBA30-b-POEGA70 and PnBA27-b-POEGA73 micelles.

Synthesis of Novel Triazole-Containing Phosphonate Polymers

2015 ◽  
Vol 68 (4) ◽  
pp. 680 ◽  
Author(s):  
Ciarán Dolan ◽  
Briar Naysmith ◽  
Simon F. R. Hinkley ◽  
Ian M. Sims ◽  
Margaret A. Brimble ◽  
...  
Keyword(s):  
Chain Transfer ◽  
Click Reaction ◽  
Raft Polymerization ◽  
Ethyl Acrylate ◽  
Polymer Chemistry ◽  
Synthesis And Characterization ◽  
Reversible Addition

The objective of this research was to develop novel phosphonate-containing polymers as they remain a relatively under researched area of polymer chemistry. Herein, we report the synthesis and characterization of 2-(1-(2-(diethoxyphosphoryl)ethyl)-1H-1,2,3-triazol-4-yl)ethyl acrylate (M1) and diethyl (2-(4-(2-acrylamidoethyl)-1H-1,2,3-triazol-1-yl)ethyl)phosphonate (M2) monomers using the copper-catalyzed azide–alkyne cycloaddition (CuAAC) ‘click’ reaction, and their subsequent polymerization via both uncontrolled and reversible addition–fragmentation chain transfer (RAFT) polymerization techniques yielding phosphonate polymers (P1–P4).

Synthesis of Novel Triazole-Containing Phosphonate Polymers

2020 ◽  
Author(s):  
C Dolan ◽  
B Naysmith ◽  
Simon Hinkley ◽  
Ian Sims ◽  
MA Brimble ◽  
...  
Keyword(s):  
Chain Transfer ◽  
Click Reaction ◽  
Raft Polymerization ◽  
Ethyl Acrylate ◽  
Polymer Chemistry ◽  
Synthesis And Characterization ◽  
Reversible Addition

© 2015 CSIRO. The objective of this research was to develop novel phosphonate-containing polymers as they remain a relatively under researched area of polymer chemistry. Herein, we report the synthesis and characterization of 2-(1-(2-(diethoxyphosphoryl)ethyl)-1H-1,2,3-triazol-4-yl)ethyl acrylate (M1) and diethyl (2-(4-(2-acrylamidoethyl)-1H-1,2,3-triazol-1-yl)ethyl)phosphonate (M2) monomers using the copper-catalyzed azide-alkyne cycloaddition (CuAAC) 'click' reaction, and their subsequent polymerization via both uncontrolled and reversible addition-fragmentation chain transfer (RAFT) polymerization techniques yielding phosphonate polymers (P1-P4).

Reversible addition fragmentation chain transfer (RAFT) polymerization of styrene in fluid CO2

e-Polymers ◽  
2004 ◽  
Vol 4 (1) ◽  
Author(s):  
Toshihiko Arita ◽  
Sabine Beuermann ◽  
Michael Buback ◽  
Philipp Vana
Keyword(s):  
Chain Transfer ◽  
Raft Polymerization ◽  
Molecular Weights ◽  
Reversible Addition ◽  
Significant Difference ◽  
Raft Agent ◽  
Successful Control ◽  
A Minor ◽  
Peak Widths

Abstract Reversible addition fragmentation chain transfer (RAFT) polymerizations of styrene in fluid CO2 have been carried out at 80°C and 300 bar using cumyl dithiobenzoate as the controlling agent in the concentration range of 3.5·10-3 to 2.1·10-2 mol/L. This is the first report on RAFT polymerization in fluid CO2. The polymerization rates were retarded depending on the employed RAFT agent concentration with no significant difference between the RAFT polymerization performed in fluid CO2 and in toluene. Full chain length distributions were analyzed with respect to peak molecular weights, indicating the successful control of radical polymerization in fluid CO2. A characterization of the peak widths may suggest a minor influence of fluid CO2 on the addition reaction of macroradicals on the dithiobenzoate group.

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