Risk Factors and Clinical Outcomes for Vancomycin-Resistant Enterococcus Colonization on Intensive Care Unit Admission

2013 ◽  
Vol 43 (2) ◽  
pp. 287 ◽  
Author(s):  
Sook-Jin Byun ◽  
Jiyeon Kang
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Intensive Care Unit Admission ◽  
Clinical Outcomes ◽  
Vancomycin Resistant Enterococcus ◽  
Vancomycin Resistant

scholarly journals Risk factors associated with the acquisition of linezolid-resistant Enterococcus faecalis

2019 ◽  
Author(s):  
Eduardo Rodríguez-Noriega ◽  
Natalia Hernández-Morfin ◽  
Elvira Garza-Gonzalez ◽  
Paola Bocanegra-Ibarias ◽  
Samantha Flores-Treviño ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Parenteral Nutrition ◽  
Intensive Care Unit Admission ◽  
Enterococcus Faecalis ◽  
Demographic Data ◽  
Previous Surgery ◽  
Previous Hospitalization ◽  
Vancomycin Resistant

Abstract Background Linezolid is used to treat vancomycin-resistant enterococcal infections. Vancomycin-resistant and -susceptible Enterococcus faecalis can develop resistance to linezolid in clinical settings with high linezolid consumption. Linezolid-resistant E. faecalis (LREF) has emerged as a major nosocomial pathogen in our hospital, in which linezolid use is considerable.Aim To define risk factors and outcomes associated with LREF infections.Methods A retrospective case-control study was designed to evaluate patients admitted to Hospital Civil de Guadalajara “Fray Antonio Alcalde” from January 2014 to October 2017. Fifty patients meeting case definitions for LREF infection and 100 controls hospitalized in the same rooms and dates as the cases were included. Clinical and demographic data were collected and analyzed.Results Risk factors for LREF, included hospitalization within the previous 6 months, intensive care unit admission, previous surgery, urinary catheterization, parenteral nutrition, and acute renal disease. Multivariate analysis identified prior exposures to linezolid [odds ratio (OR, 6.7] and clindamycin (OR, 6.7), previous hospitalization (OR, 2.8), previous surgery (OR, 5.7), and parenteral nutrition (OR, 3.4) as risk factors for LREF infection. The mortality rate for cases was 18% on the LREF versus 9% for controls.Conclusion Risk factors for LREF infections include antibiotic exposures to linezolid, clindamycin, third-generation cephalosporins, meropenem, and colistin; previous hospitalization; intensive care unit admission; previous surgery; and the use of parenteral nutrition.

Targeted Surveillance to Identify Children Colonized with Vancomycin-Resistant Enterococcus in the Pediatric Intensive Care Unit

2010 ◽  
Vol 31 (1) ◽  
pp. 95-98 ◽  
Author(s):  
Aaron M. Milstone ◽  
Lisa L. Maragakis ◽  
Karen C. Carroll ◽  
Trish M. Perl
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Pediatric Intensive Care Unit ◽  
Infection Prevention ◽  
Pediatric Intensive Care ◽  
Vancomycin Resistant Enterococcus ◽  
Prevention Strategies ◽  
Asymptomatic Patients ◽  
Vancomycin Resistant ◽  
Pediatric Infection

Performing admission surveillance cultures is a resource-intensive strategy to identify asymptomatic patients with vancomycin-resistant Enterococcus (VRE) colonization. We measured VRE prevalence among children admitted to the pediatric intensive care unit. Targeted surveillance captured 94% of VRE-colonized children and may be an effective strategy to identify VRE carriers and facilitate pediatric infection prevention strategies.

scholarly journals Risk Factors for Colonization with Extended-Spectrum β-Lactamase–producing Bacteria and Intensive Care Unit Admission

2007 ◽  
Vol 13 (8) ◽  
pp. 1144-1149 ◽  
Author(s):  
Anthony D. Harris ◽  
Jessina C. McGregor ◽  
Judith A. Johnson ◽  
Sandra M. Strauss ◽  
Anita C. Moore ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Intensive Care Unit Admission ◽  
Extended Spectrum
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