The Lifestyle Modification Coaching Program for Secondary Stroke Prevention

2013 ◽  
Vol 43 (3) ◽  
pp. 331 ◽  
Author(s):  
Heejeong Kim ◽  
Oksoo Kim
Keyword(s):  
Stroke Prevention ◽  
Lifestyle Modification ◽  
Secondary Stroke Prevention

scholarly journals Secondary Stroke Prevention in Polish Adults: Results from the LIPIDOGRAM2015 Study

2021 ◽  
Vol 10 (19) ◽  
pp. 4472
Author(s):  
Beata Labuz-Roszak ◽  
Maciej Banach ◽  
Michal Skrzypek ◽  
Adam Windak ◽  
Tomasz Tomasik ◽  
...  
Keyword(s):  
Stroke Prevention ◽  
Lifestyle Modification ◽  
Antihypertensive Drugs ◽  
Lipid Lowering ◽  
Secondary Stroke Prevention ◽  
Anticoagulant Treatment ◽  
Place Of Residence ◽  
Anticoagulation Agents ◽  
Preventive Medication ◽  
History Of

Background: The purpose of the study was to evaluate secondary stroke prevention in Poland and its association with sociodemographic factors, place of residence, and concomitant cardiovascular risk factors. Material and methods: From all patients in LIPIDOGRAM2015 Study (n = 13,724), 268 subjects had a history of ischaemic stroke and were included. Results: 165 subjects (61.6%) used at least one preventive medication. Oral antiplatelet and anticoagulation agents were used by 116 (43.3%) and 70 (26.1%) patients, respectively. Only 157 (58.6%) participants used lipid-lowering drugs, and 205 (76.5%) were treated with antihypertensive drugs. Coronary heart disease (CHD) and dyslipidaemia were associated with antiplatelet treatment (p = 0.047 and p = 0.012, respectively). A history of atrial fibrillation, CHD, and previous myocardial infarction correlated with anticoagulant treatment (p = 0.001, p = 0.011, and p < 0.0001, respectively). Age, gender, time from stroke onset, place of residence, and level of education were not associated with antiplatelet or anticoagulant treatment. Only 31.7% of patients were engaged in regular physical activity, 62% used appropriate diet, and 13.6% were current smokers. Conclusions: In Poland drugs and lifestyle modification for secondary stroke prevention are not commonly adhered to. Educational programmes for physicians and patients should be developed to improve application of effective secondary prevention of stroke.

scholarly journals Lifestyle Modification for Secondary Stroke Prevention

2016 ◽  
Vol 12 (2) ◽  
pp. 140-147 ◽  
Author(s):  
Ryan R. Bailey
Keyword(s):  
Health Care Providers ◽  
Stroke Prevention ◽  
Cognitive Skills ◽  
Recurrent Events ◽  
Lifestyle Modification ◽  
Recurrent Stroke ◽  
Secondary Stroke Prevention ◽  
Lifestyle Behaviors ◽  
Care Providers ◽  
Risk Factor Management

Of nearly 800 000 strokes that occur annually, 23% are recurrent events. Risk for disability and mortality is higher following a recurrent stroke than following a first-time stroke, which makes secondary stroke prevention a priority. Many risk factors for stroke are modifiable and amenable to improvement through lifestyle modification. Lifestyle modification can be difficult for people with stroke, however, in part because of stroke-related physical and cognitive deficits. Despite these challenges, risk factor management through lifestyle modification is important. This article reviews the multiple cardiovascular and metabolic benefits associated with the modification of several lifestyle behaviors: diet, physical activity, smoking cessation, and alcohol consumption. Health behavior theories and existing lifestyle intervention programs are also reviewed to identify important behavioral and cognitive skills that can be used to facilitate modification of health behaviors, and practical skills and suggestions for health care providers are provided.

PCV42 Antiplatelet Treatment Patterns for Secondary Stroke Prevention in the United Kingdom

2021 ◽  
Vol 24 ◽  
pp. S74
Author(s):  
J. Jiang ◽  
D. Li ◽  
J. Horrow ◽  
H. Tamada ◽  
A. Kahl ◽  
...  
Keyword(s):  
United Kingdom ◽  
Stroke Prevention ◽  
Treatment Patterns ◽  
Secondary Stroke Prevention ◽  
Antiplatelet Treatment ◽  
The United Kingdom

A Program to Improve Secondary Stroke Prevention

2011 ◽  
Vol 43 (4) ◽  
pp. 199-204 ◽  
Author(s):  
Michelle M. Menard ◽  
Don B. Smith ◽  
Cristina Taormina
Keyword(s):  
Stroke Prevention ◽  
Secondary Stroke Prevention

scholarly journals The aptamer BT200 blocks von Willebrand factor and platelet function in blood of stroke patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Katarina D. Kovacevic ◽  
Stefan Greisenegger ◽  
Agnes Langer ◽  
Georg Gelbenegger ◽  
Nina Buchtele ◽  
...  
Keyword(s):  
Platelet Function ◽  
Von Willebrand Factor ◽  
Stroke Prevention ◽  
Adenosine Diphosphate ◽  
Target Range ◽  
Large Artery ◽  
Dependent Manner ◽  
Secondary Stroke Prevention ◽  
Von Willebrand ◽  
Willebrand Factor

AbstractThe effect of conventional anti-platelet agents is limited in secondary stroke prevention, and their effects are blunted under high shear stress in the presence of increased levels of circulating von Willebrand factor (VWF). VWF is critically involved in thrombus formation at sites of stenotic extracranial/intracranial arteries. A third generation anti-VWF aptamer (BT200) has been generated which could be useful for secondary stroke prevention. To characterize the effects of BT200 in blood of patients with large artery atherosclerosis stroke (LAA). Blood samples were obtained from 33 patients with acute stroke or transient ischemic attack to measure inhibition of VWF activity and VWF-dependent platelet function. Patients who received clopidogrel or dual antiplatelet therapy did not differ in VWF dependent platelet function tests from aspirin treated patients. Of 18 patients receiving clopidogrel with or without aspirin, only 3 had a prolonged collagen adenosine diphosphate closure time, and none of the patients had ristocetin induced aggregation in the target range. BT200 concentration-dependently reduced median VWF activity from 178 to < 3%, ristocetin induced platelet aggregation from 40U to < 10U and prolonged collagen adenosine diphosphate closure times from 93 s to > 300 s. Baseline VWF activity correlated (r = 0.86, p < 0.001) with concentrations needed to reduce VWF activity to < 20% of normal, indicating that BT200 acts in a target concentration-dependent manner. Together with a long half-life supporting once weekly administration, the safety and tolerability observed in an ongoing phase I trial, and the existence of a reversal agent, BT200 is an interesting drug candidate.

Abstract W P153: HEALS Hypertension Control Program for Stroke Prevention in African American Communities

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Sunita Dodani ◽  
Sahel Arora ◽  
Dale Kraemer
Keyword(s):  
Healthy Eating ◽  
Stroke Prevention ◽  
Lifestyle Modification ◽  
Control Program ◽  
Cost Effective ◽  
Complete Information ◽  
Lifestyle Changes ◽  
Evidence Based ◽  
Church Members ◽  
Randomized Controlled Studies

Stroke is the 4th leading cause of death and a leading cause of severe, long-term disability in US. African Americans (AAs) are at an elevated risk for cerebrovascular diseases. An approach of proven efficacy is to target a major modifiable risk factor for stroke, hypertension (HTN), and to do so using lifestyle changes (i.e., diet and exercise). The objective of this study was to implement and assess the efficacy of an evidence-based, socio-culturally tailored, lifestyle intervention called HEALS (Healthy Eating And Living Spiritually) adopted and modified from PREMIER and DASH studies in AA churches in Northeast Florida. Methods: 3- months HEALS program was delivered by trained church members to the high risk church members who were; a) church parishioners 25-75 years; and b) newly or known diagnosed with HTN/pre-HTN as per JNC-7 criteria. The outcomes were analyzed using ANOVA and Wilcoxon rank tests. Results: Of the 36 eligible, 32 (90%) provided complete information on outcomes and were included in the analysis. At baseline, 15 (42%) participants were pre-HTN, 9 (25%) had Stage 1 HTN, and 12 (33%) had Stage 2 HTN. Retention of 89% was observed at the end of 3- month HEALs intervention. After the completion of the 3-months intervention, the mean reduction in systolic blood pressure (SBP) and diastolic BP (DBP) were 6.72mmHg (p=.0425) and 4.00 mmHg (p=.0073), respectively. A mean weight reduction of 1.7 kg was also significant (p=0.0023). Further, positive trends in healthy eating occurred for the majority of the participants (60%), more than half consumed dark green or other vegetables frequently, while 75% consumed at least one fruit daily or weekly. Lower percentages (44%) reported consumption of 100% fruit juices or cooked beans regularly. Conclusion: The study provided much-needed information on the translation and sustainability of evidence-based lifestyle modification in community-based settings, particularly within churches, which represent the most influential institution in the community lives of AA. HEALS program can serve as a cost-effective model for stroke prevention. Future longitudinal randomized controlled studies on HEALS effectiveness are needed.

Abstract TMP68: Vulnerability to Health Disparities and Secondary Stroke Prevention: The REGARDS Study

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
James. D Rhodes ◽  
Asikhame Oikeh ◽  
Chris Gamboa ◽  
Abimbola Fadairo ◽  
Suzanne Judd ◽  
...  
Keyword(s):  
Health Disparities ◽  
Stroke Prevention ◽  
Healthcare Providers ◽  
Lipid Lowering ◽  
Inverse Association ◽  
Secondary Stroke Prevention ◽  
Stroke Event ◽  
Point Increase ◽  
National Cohort ◽  
Regards Study

There are few studies on the effect of multiple vulnerabilities to health disparities identified in the AHRQ 2012 report on secondary stroke prevention. We examined the effects of 5 vulnerability domains (race, age, region, health insurance and income) on the prescription of secondary stroke prevention medications at discharge following hospitalization for an acute ischemic stroke (AIS) in a large, national cohort of patients admitted to unselected hospitals. Methods: We conducted a retrospective review of admissions for AIS between 2003-2012 within the REGARDS cohort. Discharge medications, insurance status, and age at time of stroke event were obtained from hospital records. Race, region and income < $20,000 were obtained from REGARDS baseline data. We constructed a vulnerability score (v score) range from 0-5, with 0 indicating no vulnerability. We examined the prevalence of each discharge medication by each vulnerability domain, score category, and by overall score using Poisson regression with a robust variance estimator. Results: 664 participants met the inclusion criteria. 132 (20%) of the study participants had ≥ 3 vulnerabilities (v score of 3-5). Participants with ≥ 3 vulnerabilities were more likely to be black (80.3%), > 75 years old (63.6%), and to report income < $20,000 (67.4%). The prevalence of receiving antithrombotic prescriptions at discharge was significantly lower in participants with ≥ 3 vulnerability domains (PR: 0.90 [95% CI: 0.82, 0.99]). The prevalence of receiving antithrombotic prescriptions was also inversely associated with a per point increase of the v score (PR: 0.96 [95% CI: 0.93, 0.99]), as were lipid- lowering prescriptions at discharge (PR: 0.95 [CI: 0.90, 0.99]). There was a non-statistically significant inverse association between ACEi/ARB prescriptions at discharge and having multiple vulnerabilities, including for 2 vulnerabilities (PR: 0.93 [CI: 0.80, 1.09]) and for ≥ 3 vulnerabilities (PR: 0.84 [CI: 0.69, 1.01]). Conclusion: The presence of multiple vulnerabilities was associated with lower adherence by healthcare providers to secondary stroke prevention recommendations for discharge prescriptions.

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