scholarly journals TARM1 Is a Novel Leukocyte Receptor Complex–Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils

2015 ◽  
Vol 195 (7) ◽  
pp. 3149-3159 ◽  
Author(s):  
Valeria Radjabova ◽  
Piero Mastroeni ◽  
Karsten Skjødt ◽  
Paola Zaccone ◽  
Bernard de Bono ◽  
...  
2001 ◽  
Vol 167 (10) ◽  
pp. 5543-5547 ◽  
Author(s):  
Rachel L. Allen ◽  
Tim Raine ◽  
Anja Haude ◽  
John Trowsdale ◽  
Michael J. Wilson

Biochimie ◽  
2012 ◽  
Vol 94 (12) ◽  
pp. 2749-2755 ◽  
Author(s):  
Guo-Ping Tian ◽  
Wu-Jun Chen ◽  
Ping-Ping He ◽  
Shi-Lin Tang ◽  
Guo-Jun Zhao ◽  
...  

2006 ◽  
Vol 58 (5-6) ◽  
pp. 481-486 ◽  
Author(s):  
Jennifer G. Sambrook ◽  
Harminder Sehra ◽  
Penny Coggill ◽  
Sean Humphray ◽  
Sophie Palmer ◽  
...  

PLoS ONE ◽  
2010 ◽  
Vol 5 (8) ◽  
pp. e12127 ◽  
Author(s):  
Maria A. Ledesma ◽  
Sara A. Ochoa ◽  
Ariadnna Cruz ◽  
Luz M. Rocha-Ramírez ◽  
Jaime Mas-Oliva ◽  
...  

2019 ◽  
Vol 7 (1) ◽  
pp. 24-36
Author(s):  
Sergio Ayala ◽  
Peter G. Thury

IL-32 is pro-inflammatory cytokine characterized by the induction of nuclear factor NF-κB activation and an important role in key cellular processes related to inflammation. We investigated whether the IL-32 expression may be involved in the mehanistic of rheumatoid arthritis through modulates the activity of NF-κB. We report that the concentrations of IL-32 are higher in the serums of RA patients than of control subjects. Results show that IL-32 induces the production of the proinflammatory cytokines IL-1-beta, IL-6, and increased NF-κB activation. We concluded that these data show that IL-32 is constitutively produced by RA synoviocytes, induces proinflammatory cytokine secretion, and activation NF-κB. IL-32 thereby may constitute a promising target to treat RA.


2005 ◽  
Vol 175 (1) ◽  
pp. 385-393 ◽  
Author(s):  
Birgit C. Viertlboeck ◽  
Felix A. Habermann ◽  
Ramona Schmitt ◽  
Martien A. M. Groenen ◽  
Louis Du Pasquier ◽  
...  

2010 ◽  
Vol 202 (2) ◽  
pp. 261-269 ◽  
Author(s):  
Nawfal R. Hussein ◽  
Richard H. Argent ◽  
Christian K. Marx ◽  
Sapna R. Patel ◽  
Karen Robinson ◽  
...  

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