scholarly journals Exacerbation of generalized plaque psoriasis after tuberculin test

2021 ◽  
Author(s):  
Alberto Corrà ◽  
Lavinia Quintarelli ◽  
Alice Verdelli ◽  
Walter Volpi ◽  
Marzia Caproni
Keyword(s):  
Lichen Planus ◽  
Plaque Psoriasis ◽  
Tuberculin Test ◽  
Skin Lesions ◽  
Psoriatic Patient ◽  
Mantoux Test ◽  
Koebner Phenomenon ◽  
Dermatological Diseases

Koebner phenomenon, also known as isomorphic response, is the appearance of active skin lesions in sites of epidermal injury. This manifestation is characteristic of different dermatological diseases, such as lichen planus, vitiligo and psoriasis. We present the case of a psoriatic patient who experienced Koebner phenomenon after Mantoux test, followed by eruption of generalized plaque psoriasis.

A Case of Lichen Planus with Prominent Koebner Phenomenon.

2001 ◽  
Vol 63 (1) ◽  
pp. 30-32
Author(s):  
Miki KANNO ◽  
Atsushi HATAMOCHI ◽  
Hiroshi SHINKAI
Keyword(s):  
Lichen Planus ◽  
Koebner Phenomenon

Dermoscopic Features of Plaque Psoriasis and Lichen Planus: New Observations

Dermatology ◽  
2003 ◽  
Vol 207 (2) ◽  
pp. 151-156 ◽  
Author(s):  
Francisco Vázquez-López ◽  
José Antonio Manjón-Haces ◽  
Cayetana Maldonado-Seral ◽  
Cristina Raya-Aguado ◽  
Narciso Pérez-Oliva ◽  
...  
Keyword(s):  
Lichen Planus ◽  
Plaque Psoriasis

Blaschkoid lichen planus: Not a Koebner phenomenon

2013 ◽  
Vol 19 (4) ◽  
Author(s):  
Nitin Ramchandra Lade ◽  
Vikrant Saoji ◽  
Adarsh Iata Singh
Keyword(s):  
Lichen Planus ◽  
Koebner Phenomenon

scholarly journals SELECTED APPLICATIONS OF DEEP NEURAL NETWORKS IN SKIN LESION DIAGNOSTIC

2021 ◽  
Vol 11 (4) ◽  
pp. 18-21
Author(s):  
Magdalena Michalska
Keyword(s):  
Neural Networks ◽  
Malignant Melanoma ◽  
Skin Lesion ◽  
Deep Neural Networks ◽  
Skin Lesions ◽  
Multiclass Classification ◽  
Features Selection ◽  
Lesion Segmentation ◽  
Dermatological Diseases ◽  
Segmentation Process

The article provides an overview of selected applications of deep neural networks in the diagnosis of skin lesions from human dermatoscopic images, including many dermatological diseases, including very dangerous malignant melanoma. The lesion segmentation process, features selection and classification was described. Application examples of binary and multiclass classification are given. The described algorithms have been widely used in the diagnosis of skin lesions. The effectiveness, specificity, and accuracy of classifiers were compared and analysed based on available datasets.

Prevalence of Tuberculosis Infection and Comparison of Multiple-puncture Liquid Tuberculin Test and Mantoux Test Among Drug Users

2002 ◽  
Vol 34 (8) ◽  
pp. 574-576 ◽  
Author(s):  
Gianluca Quaglio ◽  
Giorgio Talamini ◽  
Alessandro Lechi ◽  
Paolo Mezzelani ◽  
Fabio Lugoboni
Keyword(s):  
Drug Users ◽  
Tuberculin Test ◽  
Tuberculosis Infection ◽  
Mantoux Test ◽  
Multiple Puncture

scholarly journals Mantoux test revisited: Variability in reading tuberculin test in pediatric population

2018 ◽  
Vol 12 (08) ◽  
pp. 625-630
Author(s):  
Dimple Goel ◽  
Mukta Mantan ◽  
Gulshan R Sethi
Keyword(s):  
Primary Outcome ◽  
Interobserver Variability ◽  
Pediatric Population ◽  
Tuberculin Test ◽  
Mantoux Test ◽  
Purified Protein Derivative ◽  
Multiple Factors ◽  
Significant Difference ◽  
Trained Physician ◽  
A Prospective Study

Introduction: Mantoux test aids in the diagnosis of tuberculosis (TB), however its application and interpretation are dependent on multiple factors. Methodology: A prospective study enrolling 400 children (aged 2-12) suspected to have tuberculosis. All participants received Mantoux test with two different strengths (1 TU and 5 TU) of Purified Protein Derivative (PPD) on different forearms. The test was read by two readers after 48 ± 2 and 72 ± 2 hours. Primary outcome was difference in the size of induration when read by two readers (interobserver variability). Secondary outcomes were difference in the size of induration at different intervals, with different strengths of PPD and percentage positivity of Mantoux test in TB patients. Results: Statistically significant difference was seen in the size of induration when read by two different readers, with fair to moderate agreement when read at 48 and 72 hours (1 TU: p = 0.002, k = 0.52 and p = 0.1, k = 0.73 respectively, 5 TU: p = 0.001, k = 0.39 and p = 0.0009, k = 0.33 respectively). Tendency of under-reading occurred when size of induration was close to significant level (10-14 mm). Size of induration was similar when read at 48 or 72 hours (1 TU: p = 0.9, 5 TU: p = 1.0). Mantoux positivity rate in patients with TB was more with 5 TU as compared to 1 TU (61.2% vs. 16.3%). Conclusions: There is significant interobserver variability with a tendency to under-read around the cutoff point. The use of 5 TU PPD at 48 hours by a trained physician can aid in early and more reliable diagnosis of TB.

scholarly journals Circulating MAdCAM-1 and ITGB7 in Patients with Plaque Psoriasis and Eruptive Lichen Planus—Preliminary Data

Biology ◽  
2021 ◽  
Vol 10 (11) ◽  
pp. 1129
Author(s):  
Anna Baran ◽  
Julia Nowowiejska ◽  
Tomasz W. Kamiński ◽  
Julita A. Krahel ◽  
Iwona Flisiak
Keyword(s):  
Lichen Planus ◽  
Plaque Psoriasis ◽  
Cell Adhesion Molecule ◽  
Clinical Presentation ◽  
Skin Diseases ◽  
Upward Trend ◽  
Bowel Diseases ◽  
Group A ◽  
Inflammatory Bowel ◽  
Cell Adhesion Molecule 1

Plaque psoriasis (PSO) and lichen planus (LP) are skin diseases with some similarities in pathogenesis, comorbidities, and clinical presentation. Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and its ligand, α4β7 integrin, are involved in inflammatory bowel diseases and liver dysfunctions, which occur more frequently in PSO and LP. Serum MAdCAM-1 and ITGB7 levels in patients with plaque PSO and eruptive LP have never been studied before. The study included 42 patients with PSO, 13 with LP, and 23 controls. Serum molecules levels were evaluated using the immune–enzymatic method. ITGB7 concentration was not statistically different, both in patients with PSO and LP, compared to controls (both p > 0.05). MAdCAM-1 level was significantly lower in PSO subjects than in controls (p = 0.041), whereas in the LP group, a downward trend was observed (p = 0.088) with p = 0.0455 in ANOVA. Multiple linear regression revealed independent associations between ITGB7 and HDL and BMI and RBC in the LP group. In psoriatic patients with elevated CRP, there was an upward trend for MAdCAM-1, and also a positive correlation between MAdCAM-1 and WBC. ITGB7 and MAdCAM-1 cannot serve as markers of disease activity or liver pathology neither in patients with PSO nor LP. MAdCAM-1 might play a role as an inflammation indicator in PSO and a beneficial influence on the lipid profile in LP.

scholarly journals Immunodiagnostic Tests in the Assessment of Specific Sensitization to M. tuberculosis in Children under the Current Epidemical Situation

2021 ◽  
Vol 99 (11) ◽  
pp. 47-54
Author(s):  
L. V. Poddubnаya ◽  
E. P. Shilovа ◽  
D. A. Kudlаy ◽  
N. P. Doktorovа
Keyword(s):  
High Risk ◽  
Age Groups ◽  
Tuberculin Test ◽  
Mantoux Test ◽  
Recombinant Allergen ◽  
Tuberculous Infection ◽  
Tuberculosis Case ◽  
Degree Of Sensitization ◽  
High Degree ◽  
Immunodiagnostic Tests

The objective: to study the degree of specific sensitization according to the results of intradermal immunodiagnostic tests in children with different manifestations of tuberculosis infection under the current epidemic situation.Subjects and Methods. The degree of tuberculin sensitization was studied in 299 children from different age groups (0-14 years old) who were registered for dispensary follow-up in 2018-2019.Based on the results of a tuberculosis recombinant allergen test (TRA), the degree of specific sensitization was studied in children with tuberculin tests conversion (n = 102) and infected with Mycobacterium tuberculosis (MTB) for 2 years or more (n = 165) exposed to tuberculous infection in their families and from healthy environment, and 145 patients under 14 years old with local respiratory tuberculosis.Results. Moderate sensitization to tuberculin predominated in children with converted tuberculin test exposed to tuberculous infection in their families and those from healthy environments. According to the results of TRA test, a high degree of sensitization was observed 4.7 times more frequently in children with tuberculin test conversion exposed to tuberculosis in their families. In children from healthy environments, negative responses to TRA test were registered 2.4 times more frequently. In 73% of children infected with MTB, results of annual Mantoux tests didn’t differ much. Hyperergic reactions to TRA test in infected children exposed to tuberculous infection were 10 times more frequent than in those from healthy environments. A direct correlation was found between the high degree of sensitization to active M. tuberculosis and exposure to a tuberculosis case with a positive result of sputum test (χ2 < 0.001, p < 0.05). In the case of converted tuberculin test and infection with M. tuberculosis for 2 years or more, pronounced and hyperergic reactions to TRA test were registered with equal frequency and did not depend on the timing and duration of infection. A high risk factor and predictor of the disease development is high sensitization of the host to active M. tuberculosis which is found in patients with tuberculosis using TRA test six times more frequently versus Mantoux test (OR 5.951, 95% CI 3.548 and 9.981). The demonstrated results are important for the identification of children facing a high risk to develop active tuberculosis and preventive treatment prescription.

Sign in / Sign up

Export Citation Format

Share Document