Evaluation of LIAISON® C. difficile glutamate dehydrogenase and LIAISON® C. difficile toxin A and B in Copan FecalSwabTM samples in a three-step algorithm for the diagnosis of Clostridium difficile infection
Keyword(s):
Toxin A
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The presumptive laboratory diagnosis of <em>Clostridium</em> <em>difficile</em> infection is achieved by the means of the detection of a common antigen (glutamate dehydrogenase, GDH) in stool, then confirming the positives either by the detection of toxins A and B or by a molecular test for the detection of pathogenicity <em>locus</em>, encoding for the two toxins and for the binary toxin. A fully automated chemiluminescence system for the GDH antigen (LIAISON® C. difficile GDH) and for the detection of toxins A and B (LIAISON® C. difficile Toxin A and B) (DiaSorin, Gerenzano, Italy) allows for the performance of these tests on large numbers of samples in a short time, ensuring the traceability of the data.
2010 ◽
Vol 66
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pp. 129-134
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1992 ◽
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pp. 377-380
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Keyword(s):
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Vol 46
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pp. 1116-1117
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pp. 807-811
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