scholarly journals Clinical profile and risk factors for mortality among COVID-19 inpatients at a tertiary care centre in Bengaluru, India

Author(s):  
Yamini Marimuthu ◽  
Radhika Kunnavil ◽  
NS Anil ◽  
Sharath Burugina Nagaraja ◽  
N Satyanarayana ◽  
...  

COVID-19 is an emerging viral disease affecting more than 200 countries worldwide and it present with varied clinical profile throughout the world. Without effective drugs to cure COVID-19, early identification and control of risk factors are important measures to combat COVID-19.  This study was conducted to determine the clinical profile and risk factors associated with mortality among COVID-19 patients in a tertiary care hospital in South India. This record-based longitudinal study was conducted by reviewing the case records of COVID-19 patients admitted for treatment from June 2020 to September 2020 in a tertiary care centre in South India. The clinical details, discharge/death details, were collected and entered in MS Excel. Potential risk factors for COVID-19 mortality were analysed using univariate binomial logistic regression, generalized linear models (GLM) with Poisson distribution. Survival curves were made using the Kaplan-Meier method. Log-rank test was used to test the equality of survivor functions between the groups. Out of 854 COVID-19 patients, 56.6% were men and the mean (standard deviation) age was 45.3(17.2) years. The median survival time was significantly lesser in male COVID-19 patients (16 days) as compared to female patients (20 days). Increasing age, male gender, patients presenting with symptoms of fever, cough, breathlessness, smoking, alcohol consumption, comorbidities were significantly associated with mortality among COVID-19 patients. Patients with older age, male gender, breathlessness, fever, cough, smoking and alcohol and comorbidities need careful observation and early intervention.  Public health campaigns aimed at reducing the prevalence of risk factors like diabetes, hypertension, smoking and alcohol use are also needed.

2021 ◽  
Vol 50 (4) ◽  
pp. 704
Author(s):  
H. R. Sanjay ◽  
Habeeb Ullah Khan ◽  
M. D. Jaidev ◽  
Pavan Hegde

2014 ◽  
Vol 3 (3) ◽  
pp. 162
Author(s):  
Naval Chandra ◽  
AKrishna Prasad ◽  
TSudhir Reddy ◽  
Mallikarjun Shetty ◽  
M.V.S Subbalaxmi ◽  
...  

Author(s):  
Alka C. Kaware ◽  
Nitin H. Kamble ◽  
S. K. Mangulikar

Background: Acute respiratory infections (ARI) is an important cause of mortality and morbidity in children. In India, it constitutes 15% of under five deaths. Various risk factors are responsible for ARI in children. Study of risk factors will help to reduce the high morbidity and mortality due to ARI. The objectives were to study risk factors responsible for acute respiratory infections in children and to find out case fatality rate &/ outcome of acute respiratory infections ARI in children.Methods: A hospital based cross sectional study was done in 2013-14 in a tertiary care centre to study the risk factors associated with ARI in children. All the pediatric patients between 0-12 years admitted in a tertiary care centre at Solapur were enrolled in the study.Results: Acute respiratory tract infections (ARI) were more common in 1-4 years age group i.e. 57.31% (196). It was more common in males i.e. 64.33% (220) than females i.e. 35.67% (122). ARI was more common in lower socio-economic classes i.e. class V (50.58%), class IV (22.52%); in patients whose mothers were illiterate 43.28% and who had history of parental smoking 84.21%. Maximum patients of ARI were having history of overcrowding 75.73%, inadequate cross-ventilation 81.87% and use of smoky chullah 78.65% in their home. Statistically significant association found between ARI cases and these socio-demographic factors. 46.78% (160) were incompletely immunized and 16.37% (56) were not immunized at all. Only 36.84% (126) were completely immunized for their age. Maximum cases of ARI (50.88%) occurred in winter season followed by rainy season (26.90%). Outcome showed that 91.52% (313) were cured, while 1.75% (6) patients died due to ARI.Conclusions: The present study has identified various socio-demographic, nutritional and environmental risk factors for ARI which can be prevented by effective health education and an appropriate initiative taken by the government.


2017 ◽  
Vol 4 (3) ◽  
pp. 915 ◽  
Author(s):  
Gandhimathi K. ◽  
Pruthu Thekkur ◽  
Marie Gilbert Majella ◽  
Kalaiselvi Selvaraj ◽  
Palanivel Chinnakali ◽  
...  

Background: In developing countries, clinical profile based empirical treatment is practiced for treating pediatric scrub typhus cases. Knowledge on pattern of symptoms and signs will help in early initiation of specific treatment. This study was aimed to describe clinical profile and trends in admissions of pediatric scrub typhus cases in a tertiary teaching hospital.Methods: A record based cross sectional descriptive study was conducted among all clinically diagnosed scrub typhus pediatric (<13 years of age) cases admitted between 1st January 2011 and 31st December 2014 in a tertiary teaching hospital, South India. Data on symptoms, signs, laboratory findings, treatment and outcome were extracted from clinical case records. Data were entered and analyzed using Epi Data software.Results: Of the total 228 cases, 124 (54.4%) were males, 131 (57.4%) were less than five years of age and 88% were from rural areas. Fever (100%), vomiting (61.2%) and cough (54.8%) were the most common symptoms. Hepatomegaly (88.6%), splenomegaly (64.5%), lymphadenopathy (48.7%), edema (43.4%) and eschar (38.6%) were the common signs observed. Anemia was present in 122 (59.8%) and thrombocytopenia in 75 (33.3%) children.  Only one child (0.4%) died.  There was an increasing trend in proportion of scrub typhus cases to overall admissions from 1% to 2.2% over four-year period (2011-2014). More cases were admitted between the months of September and January.  Conclusions:Scrub typhus contributed to significant pediatric admissions in the tertiary care centre with an increase in cases over years. Treatment with doxycycline or azithromycin showed good response and mortality was very low 


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