scholarly journals Health-related quality of life measurement in asthma and chronic obstructive pulmonary disease: review of the 2009-2014 literature

2016 ◽  
Vol 11 ◽  
Author(s):  
Fabio Arpinelli ◽  
Mauro Carone ◽  
Riccardo Gioacchino ◽  
Giorgio Bertolotti
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Life Questionnaire ◽  
Obstructive Pulmonary Disease ◽  
Subjective Data ◽  
Number Of Patients ◽  
The Impact

Background: Asthma and chronic obstructive pulmonary disease (COPD) are frequent in the general population. These diseases can worsen the quality of life of people suffering from them, limiting their daily activities and disrupting their sleep at night. Some questionnaires to measure the impact of the diseases on the daily life of patients are available. The measurements of subjective outcomes have become a part of clinical practice, and are used very frequently in clinical trials. Our aim was to describe how data on HRQoL in asthma and COPD are reported in papers published in the medical literature. Methods: We identified papers on the recent respiratory drugs (chemical, not biological), that reported the HRQoL measurement and that were published from 2009 to April 2014. We planned to describe data about HRQoL, and we had no intention of comparing the degree of efficacy of drugs. Results: The most used questionnaires are the Asthma Quality of Life Questionnaire (AQLQ) and the Saint George's Respiratory Questionnaire (SGRQ). These tools, administered at the baseline and at the end of the study (and interim evaluations in the longer studies) allowed for the identification of improvements as perceived by the patient after the treatment, even if in some cases these improvements were limited and not clinically relevant. Subjective measurements have always been placed among the secondary endpoints and the number of patients (estimated for the main endpoint) has often statistically overestimated the result. In addition, it is clear that subjective data is normally reported, but rarely commented on. Conclusions: There are some methodology aspects that should be discussed in more depth, for example the necessity to express variations in the subjective perception, not as p-value but as effect-size.

Assessing Quality of Life of Patients with Advanced Chronic Obstructive Pulmonary Disease in the End of Life

2005 ◽  
Vol 21 (3) ◽  
pp. 180-187 ◽  
Author(s):  
Samantha M.C. Pang ◽  
Kin-Sang Chan ◽  
Betty P.M. Chung ◽  
Kam-Shing Lau ◽  
Edward M.F. Leung ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
End Of Life ◽  
Pulmonary Disease ◽  
Metastatic Cancer ◽  
Chinese Patients ◽  
Chronic Obstructive ◽  
Life Questionnaire ◽  
Obstructive Pulmonary Disease

Given the limitations of existing health-related quality-of-life (QOL) measures in capturing the end-of-life experience of patients with advanced chronic diseases, an empirically grounded instrument, the quality-of-life concerns in the end of life questionnaire (QOLC-E), was developed. Though it was built on the McGill quality of life questionnaire (MQOL), its sphere is more holistic and culturally specific for the Chinese patients in Hong Kong. One hundred and forty-nine patients with advanced chronic obstructive pulmonary disease (COPD) or metastatic cancer completed the questionnaire. Seven factors (28 items) which emerged from the factor analysis were grouped into four positive (support, value of life, food-related concerns, and healthcare concerns) and four negative (physical discomfort, negative emotions, sense of alienation, and existential distress) subscales. Good internal consistency and concurrent validity were shown. The results also revealed that these two groups of patients had similar QOL concerns. The validity of applying QOLC-E as an outcome measure to evaluate the effectiveness of palliative and psychoexistential interventions has yet to be tested.

scholarly journals The observational, cross sectional study to assess quality of life on patient suffering from chronic obstructive pulmonary disease in tertiary care hospital

2020 ◽  
Vol 9 (1) ◽  
pp. 162
Author(s):  
Kavita S. Joshi ◽  
Prasad R. Amrale ◽  
Sagar S. Ahire
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Well Being ◽  
Health Improvement ◽  
Chronic Obstructive ◽  
Care Hospital ◽  
Obstructive Pulmonary Disease ◽  
The Impact

Background: Chronic obstructive pulmonary disease (COPD) patients often present considerable individual medical burden in their symptoms, limitations, and well-being that complicate medical treatment. Quality of life (QOL) is an important aspect for measuring the impact of chronic diseases. HRQOL measurement facilitates the evaluation of efficacy of medical interventions and also the detection of groups at risk of psychological or behavioural problems.Methods: COPD patient attending the OPD/IPD are screened as per inclusion and exclusion criteria. After obtaining a written informed consent of eligible patient, they were enrolled in the study. QOL of patient is assessed based on a set of questionnaire i.e. COPD Assessment Test™ (CAT). The questionnaire was translated to Hindi and Marathi. Socio demographic variable like age, sex, education occupation and income are also collected. All 8 questions related to health-improvement and management of COPD. CAT scores were given to each question according to the level of impact.Results: In the total score of CAT we observed that there were 2.04% patients with very good QOL, 25.51% with good QOL, 61.22% with moderate QOL and 11.22% with poor QOL.Conclusions: We conclude that the quality of life is moderate in larger number of patient’s population. The most affected domain was the patient’s energy level. The patients enrolled had COPD from long period of time which might have affected their answer because they have been habitual with the difficulties arising from COPD.

The Impact of Treatment of Chronic Obstructive Pulmonary Disease (COPD) on Functional Status and Quality of Life of Patients

CHEST Journal ◽  
2012 ◽  
Vol 142 (4) ◽  
pp. 728A
Author(s):  
Drosos Tsavlis ◽  
Mamas Theodorou ◽  
Anna Tzoumaka ◽  
Hellie Lithoxopoulou ◽  
Panagiotis Minogiannis ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Functional Status ◽  
Pulmonary Disease ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The Impact

scholarly journals Quality of life in patients with COPD, depending on the presence of comorbidities

2020 ◽  
Vol 19 (4) ◽  
pp. 244-250
Author(s):  
Ewelina Dziedzic ◽  
Bożena Zboina ◽  
Krzysztof Cudzik ◽  
Renata Stępień
Keyword(s):  
Quality Of Life ◽  
Myocardial Infarction ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Health Condition ◽  
Survey Method ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The Impact

AbstractIntroduction. Chronic obstructive pulmonary disease (COPD) is the third leading cause of death in the world among chronic diseases. The article discusses the relationship between the quality of life of patients with COPD and the presence of diseases associated mainly with hypertension, diabetes and hyperlipidemia. The examination includes subjective and holistic assessment of the patient’s health condition, which allows to notice any disorders and deficits in the functioning of patients with this disease.Aim. The aim of the study was to determine the quality of life of patients with chronic obstructive pulmonary disease depending on the comorbidities.Material and methods. The study included 319 COPD patients treated in the Lung Diseases Clinic with chronic obstructive pulmonary disease. The study was conducted using a diagnostic survey method and analyzing medical records. The research tool assessing patients quality of life was the SGRQ questionnaire (Saint George Hospital Questionaire).Results. Respondents who had a myocardial infarction had a slightly lower quality of life in the “Impact on life subscale” (p=0.047). It was noted that patients with hypertension had a lower quality of life in the domain of “Activity” (p<0.05) and “Impact on life” (p<0.001). However, with hyperlipidemia, a lower quality of life was noticeable in the “Symptoms” (p<0.001) and “Impact on life” subscale (p=0.002).Conclusions. Exacerbation of symptoms in the course of chronic obstructive pulmonary disease, a history of myocardial infarction, hypertension and hyperlipidemia are significantly related to the decreased quality of life of patients. Prevention of these civilization diseases can prevent deterioration of the quality of life of patients.

Early bronchodilatory response to the first dose of indacaterol/glycopyrronium as an additional individual predictor of their effectiveness in the treatment of chronic obstructive pulmonary disease

2020 ◽  
Vol 22 (4) ◽  
pp. 17-22
Author(s):  
N. V. Sharova ◽  
S. L. Grishaev ◽  
D. V. Cherkashin ◽  
S. V. Efimov ◽  
M. A. Kharitonov ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Clinical Signs ◽  
Chronic Obstructive ◽  
Shortness Of Breath ◽  
Obstructive Pulmonary Disease ◽  
Long Acting ◽  
The Impact

The effectiveness of the early bronchodilatory response of the first dose of a fixed double combination of long-acting bronchodilators of various classes indacaterol/glycopyrronium and long-acting anticholinergics glycopyrronium and Tiotropium in patients suffering from stable chronic obstructive pulmonary disease is compared. It was found that in all patients included in the study and suffering from chronic obstructive pulmonary disease, changes in functional respiratory indicators were accompanied by positive and comparable dynamics of clinical signs: a decrease in the severity of shortness of breath, the impact of the disease on the quality of life and increased tolerance to physical activity. It was found that the combination of indacaterol/glycopyrronium provides rapid, pronounced and prolonged bronchodilation in patients suffering from chronic obstructive pulmonary disease compared to the separate use of glycopyrronium and Tiotropium. Consistent use of glycopyrronium and salbutamol leads to maximum bronchodilation, which makes it advisable to separate the use of prolonged bronchodilators when initiating therapy for chronic obstructive pulmonary disease. Therefore, there is a clinical feasibility of taking not only fixed combinations of bronchodilators of different classes, but also their consistent use. The results of an early bronchodilatory response to the first dose of indacaterol/glycopyrronium can be used as an additional individual predictor of their effectiveness in the treatment of chronic obstructive pulmonary disease.

Chronic Obstructive Pulmonary Disease and Dysphagia: What Have We Learned So Far and What Do We Still Need to Investigate?

2021 ◽  
pp. 1-10
Author(s):  
Renata Mancopes ◽  
Fernanda Borowsky da Rosa ◽  
Lidia Lis Tomasi ◽  
Adriane S. Pasqualoto ◽  
Catriona M. Steele
Keyword(s):  
Quality Of Life ◽  
Chronic Obstructive Pulmonary Disease ◽  
Pulmonary Disease ◽  
Self Report ◽  
Chronic Obstructive ◽  
Life Questionnaire ◽  
Obstructive Pulmonary Disease ◽  
Volume Viscosity ◽  
Patient Reported

Purpose Dysphagia is an underrecognized concern in people with chronic obstructive pulmonary disease (COPD) and may contribute to disease exacerbations. In this review article, we share information regarding dysphagia in people with COPD, synthesizing knowledge both from the literature and from studies performed in the context of a multidisciplinary clinical pulmonary rehabilitation program at the Federal University of Santa Maria in Brazil. Results This narrative review presents evidence showing that awareness of dysphagia and patient-reported symptoms of dysphagia are rare in individuals with stable COPD. However, evidence from the routine collection of patient-reported symptom data using the Eating Assessment Tool 10 and about dysphagia-related quality of life using the Swallowing Quality of Life questionnaire do suggest that dysphagia is experienced by some individuals with COPD. Several studies suggest that patients with stable COPD present with altered swallowing physiology on videofluoroscopic exams, including silent aspiration in a small number of these individuals. However, both patient self-report and clinical screening using the Volume–Viscosity Swallowing Test have been found to be poor predictors of these videofluoroscopic findings. We discuss the possibility that altered laryngeal sensation and respiratory–swallow discoordination play a role in dysphagia in people with COPD, and highlight assessment tasks that appear to have the highest sensitivity for detecting penetration–aspiration in this population. Finally, we review preliminary evidence suggesting that physical therapy techniques targeting altered respiratory muscle biomechanics may benefit swallowing in people with COPD. Knowledge gaps requiring further research are identified, and implications for clinical practice are discussed.

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