scholarly journals The place of 18F FDG PET/CT in the management of patients with eosinophilic fasciitis: a case report

Reumatismo ◽  
2021 ◽  
Vol 72 (4) ◽  
pp. 252-254
Author(s):  
N. Belfeki ◽  
N. Louarn ◽  
I. Chouchane ◽  
A. Abbadi ◽  
S. Diamantis

Eosinophilic fasciitis is a rare connective tissue disease with a clinical presentation of scleroderma-like disease. We report a case of a 36-year-old female patient with a 6-month history of progressive stiffness involving her forearms and legs with joint pain. Laboratory examinations showed hypereosinophilia and elevated C-reactive protein. 18F FDG PET/CT showed diffuse and symmetrical increased uptake in the fasciae of the upper and lower limbs, sparing both muscles and fat tissues. Guided biopsy and histologic examination confirmed the diagnosis of eosinophilic fasciitis. 18F FDG PET/CT is of great help in the diagnosis of eosinophilic fasciitis, as it can guide the biopsy where FDG uptake is strongest and also help rule out possible associated neoplasms.

2010 ◽  
Vol 31 (9) ◽  
pp. 766-772 ◽  
Author(s):  
Solene Querellou ◽  
Nathalie Keromnes ◽  
Ronan Abgral ◽  
Bruno Sassolas ◽  
Pierre-Yves Le Roux ◽  
...  

2020 ◽  
Author(s):  
Hongyan Feng ◽  
Lihong Bu

Abstract Background: In high COVID-19 prevalence region, COVID-19 disease may be incidental found in non-specific symptoms or asymptomatic patient with history of tumor who underwent 18F-FDG-PET/CT for standard oncologic indications.Case presentation: A 51-year-old woman with a 4-year history of adenoid cystic carcinoma of nasal cavity underwent 18F-FDG PET/CT for restaging during COVID-19 outbreak in Wuhan. Pneumonia lesions were characterized by 18F-FDG uptake ground-glass opacities (GGOs) and multifocal high 18F-FDG-avid patchy consolidation, and without lymph node involvement and pleural effusion. Furthermore, multiple 18F-FDG-positive lung and lumbar metastases were observed. Finally, a diagnosis of COVID-19 was made based on a positive real-time fluorescent polymerase chain reaction (RT-PCR) test of SARS-CoV-2 nucleic acid. Conclusion: The non-specific symptoms or asymptomatic cancer patients presenting 18F-FDG-positive GGOs and patchy consolidation lesions in lung may favor COVID-19, who should be quickly SARS-CoV-2 nucleic acid tested and monitored.


2016 ◽  
Vol 55 (06) ◽  
pp. 242-249 ◽  
Author(s):  
Isabell Braune ◽  
Birgit Meller ◽  
Carsten Sahlmann ◽  
Carsten Ritter ◽  
Johannes Meller ◽  
...  

SummaryThe diagnostic strategy in patients with fever or inflammation of unknown origin remains a major clinical challenge. The aim of this study was to evaluate the role of 18F-FDG-PET/CT in patients with unexplained elevated C-reactive protein with or without fever. Contribution of 18F-FDG-PET/CT to the final diagnosis was evaluated. In addition we determined whether a differentiation between patients with or without fever is clinically reasonable. Patients, methods: We retrospectively analysed 72 consecutive patients with unexplained elevated C-reactive protein levels (above 8mg/l) that underwent 18F-FDG-PET/ CT in our facility between 10/2009 and 11/2012. 18F-FDG-PET/CT was considered a so-called diagnostic scan when results decisively led to a final diagnosis and adequate therapy with a response of symptoms was initiated due to the PET/CT result. Results: In 60/72 patients (83%) a final diagnosis was established. Diagnoses included infections (58%), non-infectious inflammatory diseases (29%) and malignancies (8%). 18F-FDG-PET/CT was true positive in 47 cases (65%) and the diagnostic scan in 29 patients (40%). Sensitivity of 18F-FDG-PET/CT was 81% and specificity was 86%. Diagnostics, final diagnoses, 18F-FDG-PET/CT results, SUVmax, C-reactive protein levels and the diagnostic scan did not differ significantly between patients with fever and patients without fever. Conclusion: 18F-FDG-PET/CT is a useful method in the diagnostic workup of patients with inflammation of unknown origin. In our series there was no significant difference between patients with or without fever. Regarding 18F-FDG-PET/CT-imaging inflammation of unknown origin and unexplained fever can be joined to one entity.


2019 ◽  
Vol 15 (6) ◽  
pp. e142-e143
Author(s):  
Javier Narváez ◽  
Pablo Juarez ◽  
Isabel Morales Ivorra ◽  
Laura Rodriguez Bel ◽  
Jesus Rodriguez Moreno ◽  
...  

2018 ◽  
Vol 19 (2) ◽  
pp. 146
Author(s):  
Shamim MF Begum ◽  
Fatima Begum ◽  
Raihan Hussain ◽  
Azmal Kabir Sarker ◽  
Mizanul Hasan

<p>Spinal cord involvement secondary to non Hodgkin lymphoma (NHL) is rare and associated with quick development of neurological defects. The overall risk of central nervous system relapse in aggressive NHL ranges 2%–27% and is associated with a poor prognosis. Hence early detection is important for staging and prognostication. Magnetic Resonance Imaging (MRI) is the routinely used potential imaging modality for spinal cord metastasis. Several studies have shown the values of 18F FDG (flurodeoxyglucose) PET- CT for staging, restaging, and therapy monitoring in NHL. PET has 96% sensitivity in the detection spinal metastasis. This reported case was a 35 years old male, diagnosed as peripheral T cell lymphoma on June 2014 and was treated with chemotherapy. In January 2016 he developed swelling of lower limbs and paraparesis with bladder and bowel involvement. Duplex color Doppler of lower limbs showed normal flow and Complement Fixation Test for filariasis was negative. MRI T2W showed hyper intensity signal extending from lower cervical to all dorsal cord. The 18F FDG PET-CT was performed to restage the disease and showed intense FDG uptake in the spinal cord, extended from the lower cervical to 11<sup>th</sup> thoracic and at the level of 3<sup>rd</sup> and 4<sup>th</sup> lumbar vertebrae. The spinal cord hypermetabolism observed on PET CT scan correlated with MRI characteristics and significantly aided in the diagnosis of spinal cord involvement.    This case is reported to emphasize the usefulness 18F FDG PET-CT in restaging and follow-up of patients with NHL. PET-CT imaging can reliably identify hyper-metabolic central nervous system involvement and help not only to restage patients but also to guide new therapeutic strategies.</p><p>Bangladesh J. Nuclear Med. 19(2): 146-148, July 2016</p>


2018 ◽  
Vol 51 (6) ◽  
pp. 839-846 ◽  
Author(s):  
Han-Yu Tsai ◽  
Ming-Hsun Lee ◽  
Chih-Hsing Wan ◽  
Lan-Yan Yang ◽  
Tzu-Chen Yen ◽  
...  

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