scholarly journals Appropriateness of test request and clinical outcome: the case of autoimmune diseases

2021 ◽  
Vol 8 (1) ◽  
Author(s):  
Maria Cristina Sacchi ◽  
Roberto Guaschino ◽  
Stefania Tamiazzo ◽  
Renato Tozzoli

Objectives: To improve the appropriateness in the autoantibody test requests for proper diagnosis of systemic rheumatic autoimmune diseases, celiac disease and anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides. Methodology: Review of recommendations proposed by the Study Group in Autoimmunology (GDS-AI) of the Italian Society of Clinical Pathology and Laboratory Medicine (SIPMeL) and the European Society For Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHaN) Results: This document aims to bring to the attention of general practitioners the recommendations proposed by National and International study group to improve the appropriateness in the autoantibody test requests expecially in sytemic autoimmune and celiac disease. Conclusions: Autoimmunity is a specialistic laboratory area where the costs are extremely high compared to other diagnostics: it would therefore be very helpful and economically advantageous to align the clinicians on appropriate requests and the laboratory on useful diagnostics. In Autoimmunology, diagnostic appropriateness remains a complex and debated topic from the management, professional and economic point of view.

Cephalalgia ◽  
2002 ◽  
Vol 22 (8) ◽  
pp. 667-671 ◽  
Author(s):  
O Sjaastad ◽  
TA Fredriksen

The influence of pregnancy upon the head pain of cervicogenic headache (CEH) has been studied in 14 patients (number of pregnancies 25). Migraine was used as control group ( n = 49; number of pregnancies 116). CEH was diagnosed according to The Cervicogenic Headache International Study Group guidelines. Migraine was diagnosed according to International Headache Society (IHS) guidelines; a further requirement was that at least eight of nine solitary IHS diagnostic requirements of migraine were present. In 79%—or more—of CEH patients, attacks seemed to appear just as usual during pregnancy; in one patient, attacks stopped completely, and in two there may have been a minor reduction of attacks. A significantly lower number of migraine patients (up to 18%) were more or less uninfluenced by pregnancy (CEH vs. migraine P < 0.0001, X2 test). The lack of response to pregnancy may be a sort of biological marker in CEH. It may also help in clinically distinguishing CEH from migraine when CEH starts early in life, i.e. prior to pregnancies.


Obiter ◽  
2021 ◽  
Vol 32 (1) ◽  
Author(s):  
Eltjo Schrage

The first contribution published in this edition is an abridged version of the inaugural lecture delivered by Professor Eltjo JH Schrage on 24 August 2009 in Port Elizabeth. The Faculty of Law is honoured that such an internationally esteemed jurist accepted the appointment as first Honorary Professor of the Faculty of Law in 2009. Prof Eltjo JH Schrage was born in Groningen. He studied law at the University of Groningen, where he obtained his doctorandus, a degree which is analogous to our master’s degree. In 1975 he defended his doctoral thesis entitled Libertas est facultas naturalis. Menselijke vrijheid in een tekst van de Romeinse jurist Florentinus (Human liberty in a text of the Roman jurist Florentinus). His academic career commenced in 1969 at the Free University, Amsterdam. In 1980 he was appointed as professor at the Free University in Roman Law and Legal History. In 1998 he became the director of the Paul Scholten Institute at the University of Amsterdam. Some of his other academic appointments include the following:• Chairperson: International Study Group on the Comparative Legal History of the Law of Restitution;• Chairperson: International Study Group on the Comparative Legal History of the Law of Torts;• Visiting Professor: University of Cape Town;• Visiting Fellow: Magdalen College, Oxford University as well as visiting professor at Oxford;• Visiting Professor: University of the North (now Limpopo) in Polokwane; and• Visiting Fellow: Trinity College, Cambridge University as well as visiting professor, Cambridge. Prof Schrage has published extensively in International journals in Dutch, English, German French, and Italian. He has edited, written and contributed to more than 30 books, and written more than 100 articles. He has been the supervisor of numerous doctoral students, including Prof Marita Carnelley of the University of KwaZulu-Natal and erstwhile member of the Faculty of Law, Nelson Mandela Metropolitan University and Prof André Mukheibir, Head of Department, Private Law of the Nelson Mandela Metropolitan University. He was also the promoter of the honorary doctorate awarded by the University of Amsterdam to the former chief justice of South Africa, Arthur Chaskalson in 2002. Prof Schrage has also acted as judge in the Amsterdam court since 1981. Prof Schrage is married to Anneke Buitenbos-Schrage and the couple have four children and one grandchild.


Surgery ◽  
2015 ◽  
Vol 158 (1) ◽  
pp. 183-190 ◽  
Author(s):  
Philip R. De Reuver ◽  
Anubhav Mittal ◽  
Michael Neale ◽  
Anthony J. Gill ◽  
Jaswinder S. Samra

Surgery ◽  
2013 ◽  
Vol 153 (6) ◽  
pp. 753-761 ◽  
Author(s):  
Yakup Kulu ◽  
Alexis Ulrich ◽  
Thomas Bruckner ◽  
Pietro Contin ◽  
Thilo Welsch ◽  
...  

2018 ◽  
Vol 43 (2) ◽  
pp. 77-81 ◽  
Author(s):  
Yoichi Mizutani ◽  
Toshinori Hirai ◽  
Shigeki Nagamachi ◽  
Atsushi Nanashima ◽  
Koichi Yano ◽  
...  

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