scholarly journals Comprehension and acceptability of a patient information leaflet (pil) for antiretroviral therapy

2006 ◽  
Vol 11 (3) ◽  
Author(s):  
Betty Mwingira ◽  
Ros Dowse

The patient information leaflet (PIL) is recognised as playing a key role in informing patients about their medicines. The objectives of this research were to evaluate the readability and understanding of a PIL for the first-line ARV (antiretroviral) regimen available in the South African public health sector, and investigate its acceptability in the target Xhosa population. Opsomming Daar word algemeen aanvaar dat die pasiëntinligtingsblaadjie (PIB) ‘n sleutelrol speel in die oordra van inligting ten opsigte van medikasie aan pasiënte. Die doelwitte van hierdie navorsing was om die leesbaarheid en begrip van ‘n PIB vir die eerste-linie antiretrovirale (ARV) regimen wat in die Suid-Afrikaanse openbare gesondheidsektor beskikbaar is, te evalueer, en om die aanvaarbaarheid daarvan in ‘n teiken-Xhosabevolking te ondersoek. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Tafadzwa Dhokotera ◽  
Julia Bohlius ◽  
Adrian Spoerri ◽  
Matthias Egger ◽  
Jabulani Ncayiyana ◽  
...  

2020 ◽  
Author(s):  
Thulo Molefi

Abstract Background: Immunotherapy and molecularly targeted therapy have revolutionised the treatment of malignant melanoma however for South Africas public health sector patient population these treatment modalities are far out of reach and chemotherapy remains the only treatment option. Aim: To evaluate the outcomes of advanced melanoma and determine the need for therapies other than conventional chemotherapy in South Africas public health sector. Setting: The Department of Medical Oncology Steve Biko Academic hospital (SBAH) Pretoria South Africa. Methods: Files of patients with advanced malignant melanoma managed at SBAH from 01 January 2009 to 31 December 2019 were retrospectively reviewed. Results: One hundred files meeting the inclusion criteria were analysed 24 with regional (stage III) and 76 with metastatic (stage IV) disease. 23 (96%) patients with regional disease didnt receive adjuvant therapy and had a median time to progression (mTTP) of 12 months (95%CI; 8.9-15.0). Within the metastatic melanoma cohort 34 (79.1%) patients received chemotherapy and had a median overall survival (mOS) of 5 months (95% CI; 4.3-5.6) while patients that didnt receive chemotherapy had a mOS of 2 months (95% CI; 0.8-3.1) (p=0.213). Conclusion: These results reaffirm the impotent effects of chemotherapy in treating malignant melanoma and it is imperative that South Africas public health sector expands its armamentarium against this lethal disease.


10.29007/vpdt ◽  
2019 ◽  
Author(s):  
Tope Samuel Adeyelure ◽  
Billy Mathias Kalema

Health systems in South African comprises of both the private sector and the public sector, run by the government. Majority of the population access health services through public clinics and hospitals. Public health sectors are understaffed, with inadequate resources, especially in rural areas. Information and communication technology and its applications can be seen as a way forward to counteract some of the challenges faced in public health sectors. Telemedicine can be tool to assist in bridging the gaps in this regard. Telemedicine is health-care delivery concept that enables distant to be examined by medical practitioners using telecommunications technologies. Therefore, this research study aimed to investigate factors that influences users’ readiness to accept telemedicine in South African public health sectors environment. To achieve this objective, this study followed a positivism paradigm, supported by the quantitative research approach. Organization and Environment (in TOE framework) constructs, technology compatibility (in model of information technology implementation), perceived usefulness and perceived ease of use (in Technology Acceptance Model, (TAM))guided the development of hypotheses and their testing for this study. The findings reveal that technology, environment, organization, information quality, and security are factors that inform pre-implementation of telemedicine in South African public health sector.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Idah Mokhele ◽  
Sello Mashamaite ◽  
Pappie Majuba ◽  
Thembi Xulu ◽  
Lawrence Long ◽  
...  

Abstract Background The recently increased access to antiretroviral therapy (ART) in South Africa has placed additional strain on human and infrastructure resources of the public health sector. Capacity from private-sector General Practitioners (GPs) could be leveraged to ease the current burden on the public health sector. Methods We conducted a retrospective record review of routine electronic medical record data on a systematic sample of HIV-infected adults (≥18 years old) initiated on ART at a tertiary hospital outpatient HIV clinic in Johannesburg, South Africa and down-referred to private-GPs for continued care after stabilization on ART. We compared these patients (“GP down-referred”) to a control-cohort who remained at the referring site (“Clinic A”) and patients from a regional hospital outpatient HIV clinic not offering down-referral to GPs (“Clinic B”). Study outcomes assessed are viral load suppression (VL < 50 copies/ml) and attrition from care (all-cause-mortality or > 90-days late for a last-scheduled visit) by 12 months of follow-up following down-referral or eligibility. Results A total of 3685 patients, comprising 373 (10.1%) GP down-referred, 2599 (70.5%) clinic A controls, and 713 (19.4%) clinic B controls were included in the analysis. Overall, 1535 patients (53.3%) had a suppressed viral load. A higher portion of GP down-referred patients had a suppressed viral load compared to clinic A and B patients (65.7% vs 49.1% vs 58.9%). After adjusting for demographic and baseline clinical covariates, we found no difference in viral load suppression between GP down-referred and control patients (adjusted relative risk [aRR] for clinic A vs GP down-referred 1.0; 95% CI: 0.9–1.1), (aRR for clinic B vs GP down-referred 1.0; 95% CI: 0.9–1.2). Clinic B controls experienced the highest attrition compared to GP down-referred and clinic A controls (33.2% vs 11.3% vs 5.9%) and had a higher risk of attrition compared to GP down-referred patients (adjusted hazard ratio [aHR] 4.2; 95% CI: 2.8–6.5), whereas clinic B controls had a lower risk of attrition (aHR 0.5; 95% CI: 0.3–0.7). Conclusions and recommendations Our results show that private-GPs can contribute to caring for stabilized public sector HIV patients on life-long ART. However, they require special efforts to improve retention in care.


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