scholarly journals Cytokeratin 14 and cytokeratin 18 expressions in reduced enamel epithelium and dentigerous cyst: Possible role in oncofetal transformation and histogenesis- of follicular type of adenomatoid odontogenic tumor

2014 ◽  
Vol 18 (3) ◽  
pp. 365 ◽  
Author(s):  
DK Shruthi ◽  
MC Shivakumar ◽  
AnandS Tegginamani ◽  
B Karthik ◽  
BI Chetan
Keyword(s):  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Adenomatoid Odontogenic Tumor ◽  
Cytokeratin 18 ◽  
Enamel Epithelium ◽  
Reduced Enamel Epithelium ◽  
Cytokeratin 14

scholarly journals Study on the origin and nature of the adenomatoid odontogenic tumor by immunohistochemistry

2005 ◽  
Vol 13 (4) ◽  
pp. 406-412 ◽  
Author(s):  
Marcelo Macedo Crivelini ◽  
Ana Maria Pires Soubhia ◽  
Renata Callestini Felipini
Keyword(s):  
Benign Lesion ◽  
Collagen Iv ◽  
Odontogenic Tumor ◽  
Adenomatoid Odontogenic Tumor ◽  
Dental Follicle ◽  
Luminal Surface ◽  
Immunohistochemical Detection ◽  
Enamel Epithelium ◽  
The Subject ◽  
Reduced Enamel Epithelium

The adenomatoid odontogenic tumor (AOT) is a clinically benign lesion. Discussions about the AOT hamartomatous or neoplastic nature, and the probable odontogenic epithelial cell it originates from still exist. This research aimed to study and discuss the subject by the immunohistochemical detection of cytokeratins, laminin, collagen IV, PCNA and p53 in 8 tumor samples and 8 dental follicle samples containing reduced enamel epithelium. The results have shown that CK14 labelling indicated differentiation grades for secreting ameloblasts or ameloblasts in the post-secreting stage in the adenomatoid structure of AOT. Laminin, found on the luminal surface of adenomatoid structures, was compatible with the reduced enamel epithelium during the "protective stage of amelogenesis". PCNA specifically labelled the spindled areas and peripheral cords of the AOT, indicating that these areas are responsible for tumor growth. After considerations about pathogenesis, the authors suggested that the nature of AOT is hamartomatous with histogenesis from the reduced enamel epithelium.

scholarly journals A rare case of massif Adenomatoid Odontogenic Tumor in the anterior region of mandible: Mimicking as dentigerous cyst

2015 ◽  
Vol 27 (3) ◽  
Author(s):  
Aris Munandar ◽  
Endang Syamsudin ◽  
Melita Sylvyana ◽  
Kiki Akhmad Rizki
Keyword(s):  
Dentigerous Cyst ◽  
Final Diagnosis ◽  
Odontogenic Tumor ◽  
Radiographic Examination ◽  
Adenomatoid Odontogenic Tumor ◽  
Impacted Tooth ◽  
Unusual Site ◽  
Radiographic Features ◽  
Odontogenic Epithelium ◽  
Anterior Mandible

Background. Adenomatoid Odontogenic Tumor (AOT) is a rare tumor of epithelial origin. AOT appears in three clinico-topographic variants: follicular, extrafollicular and peripheral. The AOT was predominantly found in the upper jaw, and rarely found in mandible, especially at anterior mandible. AOT is a tumor of odontogenic epithelium having duct like structures, which may be partly cystic, and in some cases the solid lesion may be present only as masses in the wall of a large cyst. The surgical management of this lesion would be enucleation along with removal of associated impacted tooth. The prognosis for both of them is good and recurrences are very rare after complete removal of the lesion. Purpose. It is important to define final diagnose for AOT due to mimicking with DC in clinically and radiographically finding. Biopsy is still obviously necessary to the final diagnosis. Case. 15-year-old female patients reported with chief complain of swelling in anterior mandible. The swelling beginning 4 years ago, gradually progressed, with no history pain, discharge and patient is complaint about loss of sensation around anterior mandible. Aspiration revealed straw colored fluid thinking in the way of DC. The provisional diagnosis of DC was given due to clinical presentation and radiographic imaging. But the biopsy examination showed AOT due to duct-like epithelial cells was being found. Discussion. The case report illustrates characteristic clinical and radiographic features of follicular variant of AOT mimicking a DC at unusual site that is anterior mandible. AOT is thought to arise from odontogenic epithelium and associated with the impacted tooth. Rightfully AOT is a perfect imitator of DC radiographically as well as histopathologically. It usually clinically misdiagnosed as DC as both have a unilocular, well-defined radiolucency surrounding the crown of an impacted tooth. The mass was enucleated, involved teeth were extracted, and titanium plates are used to avoid pathologist fracture. The patient had uneventful postoperative recovery. Follow up of a year has not shown any evidence of recurrence. Conclusion. Follicular type of OAT could confuse us with DC if the support examination just only clinicaly finding and radiographic examination. This case could not be definitively diagnosed on clinical and radiographic features alone. Biopsy was obviously necessary to the final diagnosis.

scholarly journals Adenomatoid odontogenic tumor with dentigerous cyst: Report of a rare case with review of literature

2012 ◽  
Vol 3 (6) ◽  
pp. 244 ◽  
Author(s):  
Sunder Goyal ◽  
Soheyl Sheikh ◽  
P Shambulingappa ◽  
Balwinder Singh ◽  
Ravinder Singh ◽  
...  
Keyword(s):  
Rare Case ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Adenomatoid Odontogenic Tumor ◽  
Review Of Literature

Adenomatoid odontogenic tumor mimicking a dentigerous cyst

2005 ◽  
Vol 69 (12) ◽  
pp. 1685-1688 ◽  
Author(s):  
Miguel Bravo ◽  
David White ◽  
Lili Miles ◽  
Robin Cotton
Keyword(s):  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Adenomatoid Odontogenic Tumor

scholarly journals Dentigerous Cyst or Adenomatoid Odontogenic Tumor: Clinical Radiological and Histopathological Dilemma

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Shivesh Acharya ◽  
Ashima Goyal ◽  
Vidya Rattan ◽  
Kim Vaiphei ◽  
Sarabjot Kaur Bhatia
Keyword(s):  
Complex System ◽  
Benign Tumor ◽  
Dentigerous Cyst ◽  
Common Variant ◽  
Odontogenic Tumor ◽  
Adenomatoid Odontogenic Tumor ◽  
Dental Lamina ◽  
Slow Growing

Adenomatoid odontogenic tumor (AOT) is a well-recognised slow growing benign tumor derived from complex system of dental lamina or its remnants. This lesion is categorised into three variants of which the more common variant is follicular type which is often mistaken for dentigerous cyst. We present a case of AOT in a 14-year-old male who was misdiagnosed as dentigerous cyst. Clinical radiological and therapeutic characteristics of the case are commented on in detail.

scholarly journals Management of Dentigerous Cyst: A Review Article

2021 ◽  
Vol 2 (1) ◽  
pp. 01-04
Author(s):  
Nanda Gofur
Keyword(s):  
Epithelial Cells ◽  
Dentigerous Cyst ◽  
Inflammatory Cells ◽  
Cyst Fluid ◽  
Enamel Organ ◽  
Fluid Accumulation ◽  
Venous Flow ◽  
Dentigerous Cysts ◽  
Enamel Epithelium ◽  
Reduced Enamel Epithelium

Introduction: Dentigerous cyst is a pathological epithelial cavity that surrounds an unerupted tooth crown. Dentigerous cysts are usually associated with impacted teeth, mandibular third molars, first and second premolars and canines. Dentigerous cysts can occur at any age, but most cases of these cysts occur at the age of approximately 20 years. Men are affected more often than women. Purpose.To find out how the mechanism of dentigerous cysts. The cyst cavity is lined with epithelial cells derived from the epithelial enamel that is reduced from the tooth-forming organs. According to its pathogenesis, the pressure exerted by an erupted tooth on the follicle can block venous flow leading to accumulation of exudate between the reduced enamel epithelium and the crown of the tooth. These cysts are mostly due to fluid accumulation either between the reduced enamel epithelium and the enamel or between the layers of the enamel organ. This fluid accumulation occurs as a result of the pressure exerted by the erupting tooth on the affected follicle, which blocks venous flow, thus inducing rapid transudation of serum in the capillary walls. Discussion: The expansion of the dentigerous cyst causes the release of bone resorbing factor and an increase in the osmolarity of the cyst fluid as a result of the discharge of inflammatory cells, the discharge of residual epithelial enamel and tooth enamel, and desquamation of epithelial cells into the lumen of the cyst. In theory, the fluid will cause cystic proliferation. because the hyperosmolar content produced by cellular breakdown and cell products causes an osmotic gradient to pump fluid into the lumen of the cyst or it can also be said that an increase in the osmolarity of cyst fluid is the result of a shortcut to inflammatory cells and desquamation of epithelial cells into the lumen of the cyst resulting in a dentigerous cyst. Conclusion: The dentigerous cysts that surround the unerupted dental crowns are caused by the accumulation of fluid either between the reduced enamel epithelium or between the layers of the enamel organs. Dentigerous cysts can cause infection, pain, swelling, root dislocation, and resorption of adjacent tooth roots.

scholarly journals Adenoameloblastoma: A Dilemma in Diagnosis

2012 ◽  
Vol 13 (6) ◽  
pp. 925-929 ◽  
Author(s):  
Uma Shankar ◽  
A Radhika ◽  
Afshan Laheji ◽  
S Sakharde ◽  
S Chidambaram ◽  
...  
Keyword(s):  
Male Patient ◽  
Microscopic Examination ◽  
Rare Case ◽  
Dentigerous Cyst ◽  
Odontogenic Tumor ◽  
Anterior Region ◽  
Adenomatoid Odontogenic Tumor ◽  
Rare Finding ◽  
Odontogenic Origin ◽  
Epithelial Lesion

ABSTRACT Adenoameloblastoma or adenomatoid odontogenic tumor (AOT) is an uncommon, benign, epithelial lesion of odontogenic origin. It is a rare benign odontogenic tumor of the jaw affecting mostly young individuals with predominance in female. It occurs mostly in maxillary anterior region. On the basis of clinical and radiographical picture, it is often misdiagnosed as an odontogenic cyst. We report on a rare case of a 13-year-old male patient with a follicular variety of AOT in mandibular left anterior region which is unusual for the same. Clinically and radiographically, the lesion was mimicking as a dentigerous cyst. Later surgical enucleation was done and specimen was sent for microscopic examination and was diagnosed as AOT along with a dentinoid-like deposits which is a rare finding. How to cite this article Laheji A, Sakharde S, Chidambaram S, Gondhalekar RR, Shankar U, Radhika A. Adenoameloblastoma: A Dilemma in Diagnosis. J Contemp Dent Pract 2012;13(6): 925-929.

scholarly journals Bilateral ectopic third molar in the maxillary sinuses associated with dentigerous cyst: a case report

2021 ◽  
Author(s):  
Antoine Berberi ◽  
Georges Aoun ◽  
Bouchra Hjeij ◽  
Maissa AboulHosn ◽  
Hiba Alassaad ◽  
...  
Keyword(s):  
Dentigerous Cyst ◽  
Third Molar ◽  
Third Molars ◽  
Unerupted Tooth ◽  
Sinus Cavity ◽  
Dentigerous Cysts ◽  
Enamel Epithelium ◽  
Ectopic Third Molar ◽  
Reduced Enamel Epithelium ◽  
Maxillary Sinuses

A dentigerous cyst is an epithelial-lined odontogenic cyst formed by an accumulation of fluid between the reduced enamel epithelium and the crown of an unerupted tooth. About 70% of dentigerous cysts occur in the mandible and 30% in the maxilla and the most involved teeth are maxillary canines and maxillary third molar. Dentigerous cysts often displace the related tooth into an ectopic position. In the maxilla when the cyst expands into the sinus, usually causes total or partial occupation of the sinus cavity and can extend to the nose. We report a rare case of a 24-year-old female with bilateral maxillary third molars inside the maxillary sinuses attached to a dentigerous cyst and treated with a minimally invasive endoscopic surgery through the middle meatal meatotomy.

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