scholarly journals Can chronoscopic reading in whole body reaction time be a tool in detecting cognitive dysfunction in hypertensives? Findings from a case control study

2013 ◽  
Vol 3 (2) ◽  
pp. 233
Author(s):  
V Khode ◽  
U Rajoor ◽  
S Ramdurg ◽  
K Ruikar ◽  
S Nallulwar
Keyword(s):  
Reaction Time ◽  
Cognitive Dysfunction ◽  
Case Control Study ◽  
Case Control ◽  
Whole Body ◽  
Control Study

Whole Body Choice Reaction Time (WBCRT-C1) to Detect Cognitive Impairment in Patients with Depressive Disorder (DD): A Case-Control Study

2021 ◽  
Vol 17 ◽  
Author(s):  
Vitthal Khode ◽  
Girish Babu ◽  
Arun Gadad ◽  
Satish Patil ◽  
Komal Ruikar ◽  
...  
Keyword(s):  
Reaction Time ◽  
Depressive Disorder ◽  
Choice Reaction Time ◽  
Case Control Study ◽  
Reaction Times ◽  
Case Control ◽  
Cognitive Testing ◽  
Whole Body ◽  
Central Processing ◽  
Control Study

Background: Depressive disorder (DD) is a state of multiple neuro-psychological deficits. cognitive testing has proven beneficial in guiding treatment of depression. Since these neuro-cognitive testings require great deal of time and skill, measuring Reaction time (RT) can prove an alternative method of measure of cognition. RT is a sensitive tool to measure attention and execution. In our study whole body choice reaction time (WBCRT) is divided in to 2 chronoscopic readings WBCRT-C1and WBCRT-C2. WBCRT-C1 measures time required for central processing in the central nervous system which includes cognition and WBCRT-C2 measures total RT includes central processing and peripheral processing. Objectives: Objective of the study was to measure and compare WBCRT-C1 in DD and controls, and to assess the correlation between WBCRT-C1 with MMSE and HAM-A score. Methods: Hospital based case-control study was conducted on total 68 young subjects, 34 subjects of DD aged between 18-45yrs their reaction times were compared with similar number of age and sex matched controls. Results: WBCRT-C1 was more delayed in patients of DD (807±245 ms) than in controls (579±99ms). A significant correlation was found between WBCRT-C1 and MMSE (r=-0.7371, p=0.0001), HAM-A scores (r=0.3395 p=0.0046). Conclusion: WBCRT-C1 could be a quantitative tool to assess cognitive dysfunction in DD.

scholarly journals Correlating cognition and cortical excitability with pain in fibromyalgia: a case control study

2021 ◽  
Vol 61 (1) ◽  
Author(s):  
Vikas Kumar Tiwari ◽  
Srishti Nanda ◽  
Suvercha Arya ◽  
Uma Kumar ◽  
Ratna Sharma ◽  
...  
Keyword(s):  
Reaction Time ◽  
Sleep Quality ◽  
Daytime Sleepiness ◽  
Case Control Study ◽  
Color Word ◽  
Case Control ◽  
Corticomotor Excitability ◽  
Word Task ◽  
Control Study

Abstract Background Fibromyalgia is a chronic pain disorder characterized by widespread musculoskeletal symptoms, primarily attributed to sensitization of somatosensory system carrying pain. Few reports have investigated the impact of fibromyalgia symptoms on cognition, corticomotor excitability, sleepiness, and the sleep quality — all of which can deteriorate the quality of life in fibromyalgia. However, the existing reports are underpowered and have conflicting directions of findings, limiting their generalizability. Therefore, the present study was designed to compare measures of cognition, corticomotor excitability, sleepiness, and sleep quality using standardized instruments in the recruited patients of fibromyalgia with pain-free controls. Methods Diagnosed cases of fibromyalgia were recruited from the Rheumatology department for the cross-sectional, case-control study. Cognition (Mini-Mental State Examination, Stroop color-word task), corticomotor excitability (Resting motor threshold, Motor evoked potential amplitude), daytime sleepiness (Epworth sleepiness scale), and sleep quality (Pittsburgh sleep quality index) were studied according to the standard procedure. Results Thirty-four patients of fibromyalgia and 30 pain-free controls were recruited for the study. Patients of fibromyalgia showed decreased cognitive scores (p = 0.05), lowered accuracy in Stroop color-word task (for color: 0.02, for word: 0.01), and prolonged reaction time (< 0.01, < 0.01). Excessive daytime sleepiness in patients were found (< 0.01) and worsened sleep quality (< 0.01) were found. Parameters of corticomotor excitability were comparable between patients of fibromyalgia and pain-free controls. Conclusions Patients of fibromyalgia made more errors, had significantly increased reaction time for cognitive tasks, marked daytime sleepiness, and impaired quality of sleep. Future treatment strategies may include cognitive deficits and sleep disturbances as an integral part of fibromyalgia management.

Reaction Time and Brake Pedal Depression Following Arthroscopic Hip Surgery: A Prospective Case-Control Study

2018 ◽  
Vol 34 (5) ◽  
pp. 1463-1470.e1 ◽  
Author(s):  
George C. Balazs ◽  
Michael A. Donohue ◽  
Alaina M. Brelin ◽  
Daniel I. Brooks ◽  
Michael P. McCabe ◽  
...  
Keyword(s):  
Reaction Time ◽  
Case Control Study ◽  
Case Control ◽  
Hip Surgery ◽  
Brake Pedal ◽  
Control Study ◽  
Prospective Case Control Study

BIOKINETIC MODEL DEVELOPMENT OF RADIOIODINE-131 VIA IN VIVO GAMMA CAMERA/8-SLICE CT TECHNIQUE: CASE-CONTROL STUDY OF FELINE HYPERTHYROIDISM

2018 ◽  
Vol 18 (08) ◽  
pp. 1840035
Author(s):  
CHIH-FENG CHEN ◽  
CHAO-HSUN CHUANG ◽  
PAO-CHEN TANG ◽  
NENG-CHUNG TSENG ◽  
LUNG-FA PAN ◽  
...  
Keyword(s):  
Body Fluid ◽  
Gamma Camera ◽  
Case Control Study ◽  
Case Control ◽  
Time Dependent ◽  
Whole Body ◽  
Biokinetic Model ◽  
Stomach Body ◽  
Control Study

Objectives: A biokinetic model of iodine in the thyroid was developed and applied to a case-control study of hyperthyroid cat undertaken the NaI-131 dose administration using a gamma camera/8-slice CT with the in vivo study. Methods: The case-control hyperthyroid cats were administered 55.5 or 3.7[Formula: see text]MBq of I-131 radioactive solution and continuously surveyed by a gamma camera. The scan schedule was preset as 5- or 10-min counting per each hour from the initial time to the sixth hour, then on the 24th, 48th and 72nd hours, respectively. An in-house developed program run in the MATLAB was applied to evaluate the biokinetic model of iodine in the thyroid, in compliance with the ICRP-30 report regulations. The model was defined by five compartments (namely: stomach, body fluid, thyroid, whole body, and excretion) and allowed one to simulate the variations of time-dependent I-131 radioactive concentration among various compartments of each study subject. The numerical simulation via MATLAB was compiled with the empirical evaluation to optimize the time-dependent concentration of I-131 within the above compartments. Results: The derived biological half-life values for stomach, body fluid, thyroid, whole body, and excretion, respectively, were as follows: 17, 3, 10, 5 and 140[Formula: see text]h for hyperthyroid cat, 18, 1, 8, 2, and 40[Formula: see text]h for control #1 cat, and 22, 2, 12, 4, and 20[Formula: see text]h for control #2 cat. The cumulative radioactive doses from both gamma-ray and beta particles were assessed via a simplified algorithm as 0.135, 0.0082, and 0.005 Gy, for hyperthyroid cat, control #1, and control #2 ones, respectively. Conclusion: The derived biokinetic model was found to be helpful in the evaluation of the metabolic mechanism in case of feline hyperthyroidism. The revealed deviations from available human biomodels can be used for refining the radioiodine treatment of pets with hyperthyroidism.

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