Solitary fibrous tumor of the prostate: a case report and 5-year follow-up

A Solitary Fibrous Tumor (SFT) is a soft tissue tumor that appears exceedingly rare in the parotid gland. The literature review suggested that approximately 12%-22% of these cases behave aggressively. Besides, only 4 cases of histological malignant parotid gland SFT are reported in the English literature. We presented a 65-year-old cigarette-smoker man with a fix and tender mass over the left parotid and submandibular areas. On physical examination, the marginal branch of the facial nerve was paralyzed. The left total parotidectomy and neck dissection levels 1 and 2 were performed with preoperative embolization procedure and adjuvant radiotherapy for the patient. The results of the follow-up examination were unremarkable after 11 months. In this case report, we aimed to increase awareness on SFTs, although rare, among clinicians and pathologists. Accordingly, it should be considered in the differential diagnosis of soft-tissue tumors in the major salivary glands for better management.

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Recurrent retroperitoneal solitary fibrous tumor: a case report and review of the literature

Tumori Journal ◽

10.1177/0300891620974763 ◽

2020 ◽

pp. 030089162097476

Author(s):

Michele Manica ◽

Marco Roscigno ◽

Richard Naspro ◽

Mario Sodano ◽

Laura Milesi ◽

...

Keyword(s):

Case Report ◽

Prognostic Factor ◽

Solitary Fibrous Tumor ◽

En Bloc Resection ◽

Complete Resection ◽

En Bloc ◽

Important Prognostic Factor ◽

Mesenchymal Neoplasm ◽

Fibrous Tumor

Background: Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm described initially in visceral pleura but can occasionally involve other sites such as the urinary tract. Extrapleural localizations are often indolent but some malignant SFTs have been described. The treatment and the most important prognostic factor for SFT seem to be complete resection of the neoplasm. Case report: We report the 10-year history of a retroperitoneal SFT, which recurred twice after conservative management, and was eventually treated with en bloc resection of the mass, the bladder, and the prostate, and urinary diversion by ileal conduit. To our knowledge, this case has the longest follow-up in the literature. Conclusion: Extrapleural SFTs often have indolent but unpredictable behavior as they can recur even after many years. Some histologic features are associated with the malignancy of these tumors. Complete resection of the neoplasm is the most important prognostic factor. Patients with SFT should be considered for a very long follow-up after the surgery due to the risk of possible late recurrences.

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Solitary Fibrous Tumor of Adrenal Gland and Review of the Literature

PRILOZI ◽

10.2478/prilozi-2021-0036 ◽

2021 ◽

Vol 42 (3) ◽

pp. 63-69

Author(s):

Martina Ambardjieva ◽

Skender Saidi ◽

Rubens Jovanovic ◽

Josif Janculev ◽

Viktor Stankov ◽

...

Keyword(s):

Case Report ◽

Adrenal Gland ◽

Solitary Fibrous Tumor ◽

English Language ◽

Correct Diagnosis ◽

Tumor Patients ◽

Histopathologic Analysis ◽

Fibrous Tumor ◽

Pleural Lesion

Abstract Solitary fibrous tumor (SFT) is a rare and still controversial entity. This type of tumor first appeared in the literature as a pleural lesion, but, over the last decades, it has been reported in many extrathoracic sites. As a tumor of the adrenal gland, SFT is still rare and very uncommon, thus extensive research among the English language literature has been performed. We present here a case report of an adrenal SFT which is compared to 11 other known cases. Our case report is from a patient with SFT on the left adrenal gland, followed by mild symptoms of abdominal discomfort and hypertension. Physical examination, laboratory, and radiological tests were performed. The patient underwent surgery and the material was sent for histopathologic analysis for a definite diagnosis. Regular follow up appointments were performed over the course of two years. No recurrence of the tumor has been detected. We explain the symptoms, diagnosis, treatment, and additionally we describe the results and implications of the findings reported in the literature. Correct diagnosis is mandatory for optimal management of solitary fibrous tumor patients.

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Intravascular large B-cell lymphoma involving pleural solitary fibrous tumor: A case report and literature review

Human Pathology Case Reports ◽

10.1016/j.ehpc.2021.200530 ◽

2021 ◽

Vol 25 ◽

pp. 200530

Author(s):

Amintas Samuel ◽

Laurent Elodie ◽

Gros Audrey ◽

Sesboue Come ◽

Merlio Jean-Philippe ◽

...

Keyword(s):

Case Report ◽

Literature Review ◽

B Cell ◽

Solitary Fibrous Tumor ◽

Cell Lymphoma ◽

B Cell Lymphoma ◽

Large B Cell Lymphoma ◽

Fibrous Tumor ◽

Large B Cell

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Retroperitoneal fibrous tumor recurring as lung metastases after 10 years: a case report

Surgical Case Reports ◽

10.1186/s40792-021-01209-4 ◽

2021 ◽

Vol 7 (1) ◽

Author(s):

Kozue Matsuishi ◽

Kojiro Eto ◽

Atsushi Morito ◽

Hirokazu Hamasaki ◽

Keisuke Morita ◽

...

Keyword(s):

Case Report ◽

Solitary Fibrous Tumor ◽

Distant Metastasis ◽

Curative Resection ◽

Lung Metastases ◽

Lung Resection ◽

Left Lung ◽

Metastatic Lesion ◽

Case Presentation ◽

Fibrous Tumor

Abstract Background Solitary fibrous tumor (SFT) is a relatively rare mesenchymal tumor that mainly affects adults. Its prognosis is good after curative resection, but distant recurrences after 10 years or longer have been reported. Recurrent SFT usually arises as a local lesion; distant metastasis is rarely reported. Here, we report lung metastases that recurred a decade after excising a retroperitoneal primary SFT. Case presentation A 44-year-old woman had an SFT resected from her right retroperitoneum at our hospital. Ten years later, at age 54, she underwent a lung resection after CT showed three suspected metastases in her left lung. All three were histologically diagnosed as lung metastases from the retroperitoneal SFT. However, whereas the primary SFT had 1–2 mitotic cells/10 high power fields (HPF), the metastatic lesion increased malignancy, at 50/10 HPF. Conclusion Patients who have had resected SFTs should be carefully followed up, as malignancy may change in distant metastasis, as in this case.

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Intrapericardial solitary fibrous tumor: A case report and review of literature

Echocardiography ◽

10.1111/echo.15047 ◽

2021 ◽

Author(s):

Ali Sheikhy ◽

Aida Fallahzadeh ◽

Seyed Hossein Ahmadi‐Tafti ◽

Kaveh Hosseini ◽

Reza Mohseni‐Badalabadi ◽

...

Keyword(s):

Case Report ◽

Solitary Fibrous Tumor ◽

Review Of Literature ◽

Fibrous Tumor

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Pazopanib-associated secondary adrenal insufficiency in a patient with malignant solitary fibrous tumor

Journal of Oncology Pharmacy Practice ◽

10.1177/10781552211016081 ◽

2021 ◽

pp. 107815522110160

Author(s):

Muhammed Muhiddin Er ◽

Murat Araz ◽

Meryem Karabacak ◽

Muzaffer Uğraklı ◽

Melek Karakurt Eryılmaz ◽

...

Keyword(s):

Adrenal Insufficiency ◽

Solitary Fibrous Tumor ◽

Single Case ◽

Soft Tissue Sarcomas ◽

Pituitary Hormones ◽

Secondary Adrenal Insufficiency ◽

Primary Adrenal Insufficiency ◽

Hypoglycemic Attack ◽

Fibrous Tumor

Introduction Pazopanib is an agent that is being successfully used in soft tissue sarcomas. Some endocrine side effects may develop during pazopanib treatment. Here, we presented a case diagnosed with secondary adrenal insufficiency while being investigated for etiology of hypoglycemia which developed after pazopanib. Case report A 69-year-old male patient was operated in June 2019 due to a lung mass 26 × 18 × 10 cm in size. Pathological diagnosis revealed a solitary fibrous tumor with malignant behavior. The patient received three lines of chemotherapy. After pazopanib treatment, a hypoglycemic attack was reported. Management and outcome: Blood cortisol and ACTH (Adrenocorticotropic hormone) levels were not increased at the time of the hypoglycemic attack, and levels of other pituitary hormones were found to be normal. Electrolyte levels were in normal range. Since the counteracting hormone did not reach a sufficient level, it was considered secondary adrenal insufficiency. Hypoglycemic attacks did not occur during follow-up while taking steroid therapy and pazopanib. Discussion A single case of primary adrenal insufficiency has been reported in the literature. We here present a case who developed hypoglycemia after pazopanib and was diagnosed with drug-associated secondary adrenal insufficiency. When hypoglycemia develops during pazopanib treatment, we must be aware of adrenal insufficiency.

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